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Author Details

Senyon Choe
Joint Center for Biosciences
1986
129
49
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35063533Bone morphogenic protein 9 is a novel thermogenic hepatokine secreted in response to cold exposure.Metabolism2022
31606451Design-augmented (DA) biologics: BMP chimeras for bone and cartilage regeneration.Osteoarthritis Cartilage2020
28612305The Cardiovascular Effect of Single Injection and Toxicologic Effects of Repetitive 2-Week Intravenous Administration of Activin A/BMP-2 Chimera in Beagle Dog.Cardiovasc Toxicol2018
30396241Activin A/BMP2 Chimera (AB204) Exhibits Better Spinal Bone Fusion Properties than rhBMP2.J Korean Neurosurg Soc2018
29652075Impact of TGF-β family-related growth factors on chondrogenic differentiation of adipose-derived stem cells isolated from lipoaspirates and infrapatellar fat pads of osteoarthritic patients.Eur Cell Mater2018
26076766The activin-βA/BMP-2 chimera AB204 is a strong stimulator of adipogenesis.J Tissue Eng Regen Med2017
28423182Crystal structure of the EnvZ periplasmic domain with CHAPS.FEBS Lett2017
26846854Preparation and Characterization of Stable α-Synuclein Lipoprotein Particles.J Biol Chem2016
26446865The effects of a single intravenous injection of novel activin A/BMP-2 (AB204) on toxicity and the respiratory and central nervous systems.Drug Chem Toxicol2016
27650540Bone morphogenetic protein-9 is a potent growth inhibitor of hepatocellular carcinoma and reduces the liver cancer stem cells population.Oncotarget2016
27473602S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein.J Mol Biol2016
27085971BMP-9 enhances fibroblast growth factor 21 expression and suppresses obesity.Biochim Biophys Acta2016
25790378Biphasic effects of FGF2 on adipogenesis.PLoS One2015
26301538In Situ Formation of an Azo Bridge on Proteins Controllable by Visible Light.J Am Chem Soc2015
26563344Activin A/BMP2 chimera AB235 drives efficient redifferentiation of long term cultured autologous chondrocytes.Sci Rep2015
26107293The toxicological evaluation of repetitive 2- and 4-week intravenous injection of Activin A/BMP-2 chimera (AB204) into rats.Regul Toxicol Pharmacol2015
24038612Ligand- and stage-dependent divergent functions of BMP signaling in the differentiation of embryonic skeletogenic progenitors in vitro.J Bone Miner Res2014
25458539Engineering TGF-β superfamily ligands for clinical applications.Trends Pharmacol Sci2014
25070479An Activin A/BMP2 chimera, AB215, blocks estrogen signaling via induction of ID proteins in breast cancer cells.BMC Cancer2014
25100748Regulation of FSHβ induction in LβT2 cells by BMP2 and an Activin A/BMP2 chimera, AB215.J Endocrinol2014
24958726Solution NMR structure and functional analysis of the integral membrane protein YgaP from Escherichia coli.J Biol Chem2014
24559319MB109 as bioactive human bone morphogenetic protein-9 refolded and purified from E. coli inclusion bodies.Microb Cell Fact2014
24555430Characterization of Activin/BMP2 chimera, AB204, formulated for preclinical studies.Protein Pept Lett2014
24525125Drug screening strategy for human membrane proteins: from NMR protein backbone structure to in silica- and NMR-screened hits.Biochem Biophys Res Commun2014
24692083An activin A/BMP2 chimera, AB204, displays bone-healing properties superior to those of BMP2.J Bone Miner Res2014
24311780Designer nodal/BMP2 chimeras mimic nodal signaling, promote chondrogenesis, and reveal a BMP2-like structure.J Biol Chem2014
24439409BMP-9 as a potent brown adipogenic inducer with anti-obesity capacity.Biomaterials2014
23349867Detergent/nanodisc screening for high-resolution NMR studies of an integral membrane protein containing a cytoplasmic domain.PLoS One2013
24064062Anti-wrinkle effect of bone morphogenetic protein receptor 1a-extracellular domain (BMPR1a-ECD).BMB Rep2013
23721747Advances in NMR structures of integral membrane proteins.Curr Opin Struct Biol2013
23737939MstX and a putative potassium channel facilitate biofilm formation in Bacillus subtilis.PLoS One2013
23790977Reconstruction of radial bone defect using gelatin sponge and a BMP-2 combination graft.BMB Rep2013
23500646Activin/BMP2 chimeric ligands direct adipose-derived stem cells to chondrogenic differentiation.Stem Cell Res2013
23520526Hypoxia antagonizes glucose deprivation on interleukin 6 expression in an Akt dependent, but HIF-1/2α independent manner.PLoS One2013
22609626Facile backbone structure determination of human membrane proteins by NMR spectroscopy.Nat Methods2012
23063122A structural basis for the assembly and functions of a viral polymer that inactivates multiple tumor suppressors.Cell2012
22493239Cotranslational cis-phosphorylation of the COOH-terminal tail is a key priming step in the maturation of cAMP-dependent protein kinase.Proc Natl Acad Sci U S A2012
21422294Mechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27.Proc Natl Acad Sci U S A2011
22026995BMPs and their clinical potentials.BMB Rep2011
22073163Designer TGFβ superfamily ligands with diversified functionality.PLoS One2011
21533578Transgenic microalgae expressing Escherichia coli AppA phytase as feed additive to reduce phytate excretion in the manure of young broiler chicks.Appl Microbiol Biotechnol2011
21389213Separation of domain contacts is required for heterotetrameric assembly of functional NMDA receptors.J Neurosci2011
21465615Polymer-based cell-free expression of ligand-binding family B G-protein coupled receptors without detergents.Protein Sci2011
20371380Structure of the MthK RCK in complex with cadmium.J Struct Biol2010
20849081The functionally active Mistic-fused histidine kinase receptor, EnvZ.Biochemistry2010
20945360Rapid exploration of the folding topology of helical membrane proteins using paramagnetic perturbation.Protein Sci2010
20484413Bone morphogenetic protein-2 and -6 heterodimer illustrates the nature of ligand-receptor assembly.Mol Endocrinol2010
20498088Membrane domain structures of three classes of histidine kinase receptors by cell-free expression and rapid NMR analysis.Proc Natl Acad Sci U S A2010
20567515BMP-2/6 heterodimer is more effective than BMP-2 or BMP-6 homodimers as inductor of differentiation of human embryonic stem cells.PLoS One2010
20594156Structure of the cytoplasmic segment of histidine kinase receptor QseC, a key player in bacterial virulence.Protein Pept Lett2010
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Collaborators

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Co-authored papers 31
School of Pharmacy , Chapman University
Co-authored papers 17
ETH Zurich
Co-authored papers 13
Inc., Salk Institute for Biological Studies
Co-authored papers 9
Qualcomm Institute, University of California San Diego
Co-authored papers 8
Friedman Brain Institute, Icahn School of Medicine at Mount Sinai
Co-authored papers 7
Stanford University
Co-authored papers 7
ETH Zurich
Co-authored papers 5
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Co-authored papers 4
Ecole Polytechnique Federale de Lausanne (EPFL), University of Lausanne
Co-authored papers 3
University of California San Francisco
Co-authored papers 2
university of california los angeles
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
Co-authored papers 2
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 2
Janssen Research and Development LLC, Janssen Pharmaceutica N.V.
Co-authored papers 2
The Salk Institute for Biological Studies
Co-authored papers 2
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
Lawrence Berkeley National Laboratory
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
iHuman Institute, ShanghaiTech University
Co-authored papers 1
David Geffen School of Medicine, University of California los angeles
Co-authored papers 1
National Center for Microscopy and Imaging Research, University of California
Co-authored papers 1
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University of Oxford
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University of California San Diego
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