Author details

Full Name

Gary P Sims

Affiliation

ORCID

Career Start Year

1991

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37442582	Oxidised IL-33 drives COPD epithelial pathogenesis ST2-independent RAGE/EGFR signalling complex.		2023
35675168	Heavy Chain Constant Region Usage in Antibodies to Peptidylarginine Deiminase 4 as a Marker of Disease Subsets in Rheumatoid Arthritis.	Arthritis Rheumatol	2022
34008986	Characterization of Citrullination Sites in Neutrophils and Mast Cells Activated by Ionomycin via Integration of Mass Spectrometry and Machine Learning.	Journal of Proteome Research	2021
32637608	Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal.	Sci Adv	2020
32182251	LOX-1: A potential driver of cardiovascular risk in SLE patients.	PLoS ONE	2020
30459279	Humanised effector-null FcÎ³RIIA antibody inhibits immune complex-mediated proinflammatory responses.	Ann Rheum Dis	2019
29403504	Perspective on Protein Arginine Deiminase Activity-Bicarbonate Is a pH-Independent Regulator of Citrullination.	Frontiers in Immunology	2018
30323221	Evidence for a direct link between PAD4-mediated citrullination and the oxidative burst in human neutrophils.	Scientific Reports	2018
29644082	Characterisation of anifrolumab, a fully human anti-interferon receptor antagonist antibody for the treatment of systemic lupus erythematosus.	Lupus Sci Med	2018
29070531	Affinity maturation shapes the function of agonistic antibodies to peptidylarginine deiminase type 4 in rheumatoid arthritis.	Ann Rheum Dis	2018
28993780	Spontaneous Secretion of the Citrullination Enzyme PAD2 and Cell Surface Exposure of PAD4 by Neutrophils.	Frontiers in Immunology	2017
26078491	Characterization of the Hypercitrullination Reaction in Human Neutrophils and Other Leukocytes.	Mediators of Inflammation	2015
25706559	S100A9 induced inflammatory responses are mediated by distinct damage associated molecular patterns (DAMP) receptors in vitro and in vivo.	PLoS ONE	2015
26212055	Aging and Systemic Lupus Erythematosus - Immunosenescence and Beyond.	Current Aging Science	2015
23559480	RAGE inhibits human respiratory syncytial virus syncytium formation by interfering with F-protein function.	Journal of General Virology	2013
24081950	RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.	Journal of Experimental Medicine	2013
22262795	Opposing roles of membrane and soluble forms of the receptor for advanced glycation end products in primary respiratory syncytial virus infection.	J Infect Dis	2012
21902688	A glycoengineered anti-CD19 antibody with potent antibody-dependent cellular cytotoxicity activity in vitro and lymphoma growth inhibition in vivo.	Br J Haematol	2011
21118058	Emerging small molecule and biological therapeutic approaches for the treatment of autoimmunity.	Expert Opinion on Investigational Drugs	2011
21809320	Isolation of human B cell populations.	Current Protocols in Immunology	2011
20192808	HMGB1 and RAGE in inflammation and cancer.	Annual Review of Immunology	2010
20133931	Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease.	American Journal of Respiratory and Critical Care Medicine	2010
20131230	Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture.	Arthritis Rheum	2010
19278337	Innate immune signals modulate antiviral and polyreactive antibody responses during severe respiratory syncytial virus infection.	Journal of Infectious Diseases	2009
18475307	Genomic-based high throughput screening identifies small molecules that differentially inhibit the antiviral and immunomodulatory effects of IFN-alpha.	Mol Med	2008
17312131	IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells.	Journal of Immunology	2007
17330259	The existence of human TII B cells remains unproven: comment on the article by Daridon et al.		2007
17947662	Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration.	Journal of Immunology	2007
17641030	Modulatory effects of 1,25-dihydroxyvitamin D3 on human B cell differentiation.	Journal of Immunology	2007
18432976	Isolation of human B cell populations.	Current Protocols in Immunology	2006
16272303	Stepwise differentiation of CD4 memory T cells defined by expression of CCR7 and CD27.	Journal of Immunology	2005
15701725	Identification and characterization of circulating human transitional B cells.	Blood	2005
16301650	Developmental changes in the human heavy chain CDR3.	Journal of Immunology	2005
16339522	IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells.	Journal of Immunology	2005
12882828	Spontaneous production of anti-IFN-alpha and anti-IL-12 autoantibodies by thymoma cells from myasthenia gravis patients suggests autoimmunization in the tumor.	International Immunology	2003
14592891	Antibodies in myasthenia gravis and related disorders.	Annals of the New York Academy of Sciences	2003
14592881	Scenarios for autoimmunization of T and B cells in myasthenia gravis.	Annals of the New York Academy of Sciences	2003
12379775	Antibodies to acetylcholine receptor in parous women with myasthenia: evidence for immunization by fetal antigen.	Laboratory Investigation	2002
12503684	Identification and phylogenetic analysis of morphologically similar naked amoebae using small subunit ribosomal RNA.	Journal of Eukaryotic Microbiology	2002
11489973	Somatic hypermutation and selection of B cells in thymic germinal centers responding to acetylcholine receptor in myasthenia gravis.	Journal of Immunology	2001
11360823	Application of scFv-phage display to analysis of B-cell clones proliferating in the salivary glands of a patient with SjÃ¶gren's syndrome.	Disease Markers	2000
10229578	Primary and secondary structure of the small-subunit ribosomal RNA of the naked, marine amoeba Vannella anglica: phylogenetic implications.	Journal of Molecular Evolution	1999
1762901	The role of two surface exposed loops in transcription activation by the Escherichia coli CRP and FNR proteins.	Nucleic Acids Research	1991