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Author Details

Louise C Showe
The Wistar Institute
1975
147
54
Sarah J Ratcliffe (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
34432273Functional Annotation of MicroRNAs Using Existing Resources.Methods Mol Biol2022
35420632Telomere dysfunction implicates POT1 in patients with idiopathic pulmonary fibrosis.J Exp Med2022
36402891GediNET for discovering gene associations across diseases using knowledge based machine learning approach.Sci Rep2022
33270606Methyltransferase inhibitors restore SATB1 protective activity against cutaneous T cell lymphoma in mice.J Clin Invest2021
33675198Clinical presentation of COVID-19 - a model derived by a machine learning algorithm.J Integr Bioinform2021
33497421A multi-omics approach to Epstein-Barr virus immortalization of B-cells reveals EBNA1 chromatin pioneering activities targeting nucleotide metabolism.PLoS Pathog2021
34447895Lack of Atorvastatin Effect on Monocyte Gene Expression and Inflammatory Markers in HIV-1-infected ART-suppressed Individuals at Risk of non-AIDS Comorbidities.Pathog Immun2021
33278709PAF-R on activated T cells: Role in the IL-23/Th17 pathway and relevance to multiple sclerosis.Immunobiology2021
32054837Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus.Nat Commun2020
30487137A Gene Expression Classifier from Whole Blood Distinguishes Benign from Malignant Lung Nodules Detected by Low-Dose CT.Cancer Res2019
31893252Evidence for Persistent Monocyte and Immune Dysregulation After Prolonged Viral Suppression Despite Normalization of Monocyte Subsets, sCD14 and sCD163 in HIV-Infected Individuals.Pathog Immun2019
31831736Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization.Nat Commun2019
31253727NK Response Correlates with HIV Decrease in Pegylated IFN-α2a-Treated Antiretroviral Therapy-Suppressed Subjects.J Immunol2019
30967398N<sup>6</sup>-Methylation of Adenosine of <i>FZD10</i> mRNA Contributes to PARP Inhibitor Resistance.Cancer Res2019
27592800TIGIT and Helios Are Highly Expressed on CD4<sup>+</sup> T Cells in Sézary Syndrome Patients.J Invest Dermatol2017
28436945ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay.Nat Struct Mol Biol2017
28393830Structural and functional analysis of the human POT1-TPP1 telomeric complex.Nat Commun2017
28583307The effect of timing of influenza vaccination and sample collection on antibody titers and responses in the aged.Vaccine2017
26869349The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis.Nat Commun2016
26555708HIV-1-negative female sex workers sustain high cervical IFNÉ¿, low immune activation, and low expression of HIV-1-required host genes.Mucosal Immunol2016
27588486Race-related differences in antibody responses to the inactivated influenza vaccine are linked to distinct pre-vaccination gene expression profiles in blood.Oncotarget2016
27922818Age-related changes in the gene expression profile of antigen-specific mouse CD8+ T cells can be partially reversed by blockade of the BTLA/CD160 pathways during vaccination.Aging (Albany NY)2016
27754870Transgenic Expression of the Mitochondrial Chaperone TNFR-associated Protein 1 (TRAP1) Accelerates Prostate Cancer Development.J Biol Chem2016
27803105BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer.Cancer Res2016
26967249Age-related changes in the transcriptome of antibody-secreting cells.Oncotarget2016
25704169Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cells.Acta Physiol (Oxf)2015
26474164In-Depth, Label-Free Analysis of the Erythrocyte Cytoplasmic Proteome in Diamond Blackfan Anemia Identifies a Unique Inflammatory Signature.PLoS One2015
26578789Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes.Proc Natl Acad Sci U S A2015
26257282Interaction between TBP and Condensin Drives the Organization and Faithful Segregation of Mitotic Chromosomes.Mol Cell2015
26468528Identification of MEF2B, EBF1, and IL6R as Direct Gene Targets of Epstein-Barr Virus (EBV) Nuclear Antigen 1 Critical for EBV-Infected B-Lymphocyte Survival.J Virol2015
26160834AKAP4 is a circulating biomarker for non-small cell lung cancer.Oncotarget2015
25891346Romidepsin in peripheral and cutaneous T-cell lymphoma: mechanistic implications from clinical and correlative data.Br J Haematol2015
23792457CD164 and FCRL3 are highly expressed on CD4+CD26- T cells in Sézary syndrome patients.J Invest Dermatol2014
25207202Inflammation and Its Correlates in Regenerative Wound Healing: An Alternate Perspective.Adv Wound Care (New Rochelle)2014
25314618Comparative functional genomics of adaptation to muscular disuse in hibernating mammals.Mol Ecol2014
24948111ID1 promotes breast cancer metastasis by S100A9 regulation.Mol Cancer Res2014
24859450The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells.Nat Immunol2014
24587128Identification of a 251 gene expression signature that can accurately detect M. tuberculosis in patients with and without HIV co-infection.PLoS One2014
24569637Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line.Heredity (Edinb)2014
24503249Isoform-level gene signature improves prognostic stratification and accurately classifies glioblastoma subtypes.Nucleic Acids Res2014
22430205The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis.Oncogene2013
23907639Retraction: Sp100 as a potent tumor suppressor: accelerated senescence and rapid malignant transformation of human fibroblasts through modulation of an embryonic stem cell program.Cancer Res2013
24003254The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis.Sci Signal2013
23689370Single cell analysis of RNA-mediated histone H3.3 recruitment to a cytomegalovirus promoter-regulated transcription site.J Biol Chem2013
23532732MAPK pathway activation leads to Bim loss and histone deacetylase inhibitor resistance: rationale to combine romidepsin with an MEK inhibitor.Blood2013
23271702Correlates of relative resistance against low-dose rectal simian immunodeficiency virus challenges in peripheral blood mononuclear cells of vaccinated rhesus macaques.J Leukoc Biol2013
23303179Cyclophilin D extramitochondrial signaling controls cell cycle progression and chemokine-directed cell motility.J Biol Chem2013
21840619IL-12 inhibits glucocorticoid-induced T cell apoptosis by inducing GMEB1 and activating PI3K/Akt pathway.Immunobiology2012
23243612The peripheral immune response and lung cancer prognosis.Oncoimmunology2012
22954256Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles.BMC Med Genomics2012
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Collaborators

The Wistar Institute
Co-authored papers 46
Wistar Institute
Co-authored papers 9
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 7
The Wistar Institute
Co-authored papers 6
Co-authored papers 5
Institute of Arctic Biology, University of Alaska Fairbanks
Co-authored papers 5
Merck & Co., Inc.
Co-authored papers 4
University of Pennsylvania School of Medicine
Co-authored papers 4
Co-authored papers 4
University of Virginia
Co-authored papers 3
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 3
Co-authored papers 3
University of Michigan ann arbor
Co-authored papers 2
Weill Cornell Medical College
Co-authored papers 2
Co-authored papers 2
Seattle Children's Hospital
Co-authored papers 2
Ellen and Ronald Caplan Cancer Center, The Wistar Institute
Co-authored papers 2
The Wistar Institute
Co-authored papers 2
University of Pennsylvania Perelman School of Medicine
Co-authored papers 2
University of Texas Health San Antonio (UTHSA)
Co-authored papers 2
Center for Quantitative Life Sciences, Oregon State University
Co-authored papers 1
Massachusetts General Hospital
Co-authored papers 1
University of Minnesota
Co-authored papers 1
Co-authored papers 1
University of Delaware
Co-authored papers 1
Harvard T. H. Chan School of Public Health
Co-authored papers 1
Stony Brook University
Co-authored papers 1
Co-authored papers 1
Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine
Co-authored papers 1
Co-authored papers 1