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Author Details

Leah M Prentice
British Columbia Women's Hospital and Health Centre
2004
36
28
PMIDPaper TitleJournal TitlePublished Year
36714130The practice of genomic medicine: A delineation of the process and its governing principles.Front Med (Lausanne)2023
34687784Optimization of magnetic bead-based nucleic acid extraction for SARS-CoV-2 testing using readily available reagents.J Virol Methods2022
35442193The Clinical Variant Analysis Tool: Analyzing the evidence supporting reported genomic variation in clinical practice.Genet Med2022
32792599Molecular characterization of invasive and in situ squamous neoplasia of the vulva and implications for morphologic diagnosis and outcome.Mod Pathol2021
31714258c-KIT Analysis and Targeted Molecular Sequencing of Mesonephric Carcinomas of the Female Genital Tract.Am J Surg Pathol2020
30428062Iatrogenic endometriosis harbors somatic cancer-driver mutations.Hum Reprod2019
31200828Selumetinib in patients receiving standard pemetrexed and platinum-based chemotherapy for advanced or metastatic KRAS wildtype or unknown non-squamous non-small cell lung cancer: A randomized, multicenter, phase II study. Canadian Cancer Trials Group (CCTG) IND.219.Lung Cancer2019
29698444Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.PLoS One2018
28830562Ciliated muconodular papillary tumors of the lung with KRAS/BRAF/AKT1 mutation.Diagn Pathol2017
28436987Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes.Nat Genet2017
27182968Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer.Nat Genet2016
25572802A co-culture genome-wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation.Breast Cancer Res2015
25692284Multifocal endometriotic lesions associated with cancer are clonal and carry a high mutation burden.J Pathol2015
23765252Ovarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN mutation profiles.Mod Pathol2014
25060187TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data.Genome Res2014
24658001Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4.Nat Genet2014
23780408Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling.J Pathol2013
24116245Correction: Type-Specific Cell Line Models for Type-Specific Ovarian Cancer Research.PLoS One2013
23880734Biomarker-based ovarian carcinoma typing: a histologic investigation in the ovarian tumor tissue analysis consortium.Cancer Epidemiol Biomarkers Prev2013
23845225Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study.Lancet Oncol2013
24023729Type-specific cell line models for type-specific ovarian cancer research.PLoS One2013
22187960Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers.N Engl J Med2012
22916110Mutation discovery in regions of segmental cancer genome amplifications with CoNAn-SNV: a mixture model for next generation sequencing of tumors.PLoS One2012
22495314The clonal and mutational evolution spectrum of primary triple-negative breast cancers.Nature2012
22653804Use of mutation profiles to refine the classification of endometrial carcinomas.J Pathol2012
22282309BRCA1 and BRCA2 mutations correlate with TP53 abnormalities and presence of immune cell infiltrates in ovarian high-grade serous carcinoma.Mod Pathol2012
2222366014-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma.Proc Natl Acad Sci U S A2012
21381030Subtype-specific mutation of PPP2R1A in endometrial and ovarian carcinomas.J Pathol2011
22069496Mll5 is required for normal spermatogenesis.PLoS One2011
21527035The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent.BMC Genomics2011
20942669ARID1A mutations in endometriosis-associated ovarian carcinomas.N Engl J Med2010
19812674Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution.Nature2009
19053170Ovarian carcinoma subtypes are different diseases: implications for biomarker studies.PLoS Med2008
18005407Kisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma.BMC Med2007
16027731NRG1 gene rearrangements in clinical breast cancer: identification of an adjacent novel amplicon associated with poor prognosis.Oncogene2005
15289306Overexpression of the anti-adhesin podocalyxin is an independent predictor of breast cancer progression.Cancer Res2004
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Collaborators

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Memorial Sloan Kettering Cancer Center
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University of British Columbia
Co-authored papers 6
Memorial Sloan Kettering Cancer Center
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University of Calgary
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University of British Columbia
Co-authored papers 6
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Canada British Columbia Cancer Research Centre, University of British Columbia
Co-authored papers 5
Ferdowsi University of Mashhad
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Co-authored papers 4
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 3
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University of Toronto.
Co-authored papers 3
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Co-authored papers 2
Yong Loo Lin School of Medicine, National University of Singapore
Co-authored papers 2
Cedars-Sinai Medical Center
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School of Clinical Medicine, University of NSW Sydney, Lowy Cancer Research Centre
Co-authored papers 2
Grady Memorial Hospital
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University of British Columbia
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