Author details

Full Name

Kenichi Okuda

Affiliation

ORCID

Career Start Year

2004

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37349353	Development of a novel air-liquid interface airway tissue equivalent model for in vitro respiratory modeling studies.	Sci Rep	2023
38016030	Proximal and Distal Bronchioles Contribute to the Pathogenesis of Non-Cystic Fibrosis Bronchiectasis (NCFB).		2023
37285404	Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration.		2023
37399831	Associations of COVID-19 symptoms with omicron subvariants BA.2 and BA.5, host status, and clinical outcomes in Japan: a registry-based observational study.		2023
36563691	An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2.	Cell Host Microbe	2023
35194605	A model of persistent post SARS-CoV-2 induced lung disease for target identification and testing of therapeutic strategies.	bioRxiv	2022
35816430	Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease.	Am J Respir Crit Care Med	2022
35879412	Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.	Nat Genet	2022
36142171	Mucins and CFTR: Their Close Relationship.	International Journal of Molecular Sciences	2022
35677067	A Multitrait Locus Regulates Sarbecovirus Pathogenesis.	bioRxiv	2022
35363522	Mucus concentration-dependent biophysical abnormalities unify submucosal gland and superficial airway dysfunction in cystic fibrosis.	Science advances	2022
35862771	A Multitrait Locus Regulates Sarbecovirus Pathogenesis.	mBio	2022
35857635	SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice.	Sci Transl Med	2022
35355018	Human distal lung maps and lineage hierarchies reveal a bipotent progenitor.	Nature	2022
35852317	Small-Molecule-Induced Activation of Cellular Respiration Inhibits Biofilm Formation and Triggers Metabolic Remodeling in Staphylococcus aureus.	mBio	2022
35217407	Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications.	eBioMedicine	2022
33321047	Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia.	American Journal of Respiratory and Critical Care Medicine	2021
33831321	The Big Impact of Small Airway pH.	American Journal of Respiratory Cell and Molecular Biology	2021
32946266	FOXL1 Regulates Lung Fibroblast Function via Multiple Mechanisms.	American Journal of Respiratory Cell and Molecular Biology	2020
32298651	Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis.	Cell	2020
33140061	Integrated Single-Cell Atlases Reveal an Oral SARS-CoV-2 Infection and Transmission Axis.	medRxiv	2020
32526206	SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.	Cell	2020
33031744	A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice.	Cell	2020
33184236	SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo.	Science	2020
30692051	Exacerbation of chronic pulmonary aspergillosis was associated with a high rebleeding rate after bronchial artery embolization.	Respiratory Investigation	2019
31570396	Roles of lytic transglycosylases in biofilm formation and Î²-lactam resistance in methicillin-resistant .	Antimicrobial Agents and Chemotherapy	2019
30352166	Localization of Secretory Mucins MUC5AC and MUC5B in Normal/Healthy Human Airways.	American Journal of Respiratory and Critical Care Medicine	2019
31524632	IL-1Î² dominates the promucin secretory cytokine profile in cystic fibrosis.	Journal of Clinical Investigation	2019
30973754	XBP1S Regulates MUC5B in a Promoter Variant-Dependent Pathway in Idiopathic Pulmonary Fibrosis Airway Epithelia.	American Journal of Respiratory and Critical Care Medicine	2019
29225246	Acute Arterial Thrombosis during Postoperative Adjuvant Cisplatin-based Chemotherapy for Completely Resected Lung Adenocarcinoma.	Internal Medicine	2018
30577829	Detection of bacterial DNA from central venous catheter removed from patients by next generation sequencing: a preliminary clinical study.	Annals of Clinical Microbiology and Antimicrobials	2018
29491850	The Composition and Structure of Biofilms Developed by Isolated from Cardiac Pacemaker Devices.	Frontiers in Microbiology	2018
29134109	Erratum: Author Correction: Norgestimate inhibits staphylococcal biofilm formation and resensitizes methicillin-resistant to Î²-lactam antibiotics.	npj Biofilms and Microbiomes	2017
28758016	Norgestimate inhibits staphylococcal biofilm formation and resensitizes methicillin-resistant to Î²-lactam antibiotics.	npj Biofilms and Microbiomes	2017
28840097	A case of delayed exacerbation of interstitial lung disease after discontinuation of temsirolimus.	Respiratory Medicine Case Reports	2017
28712741	Epithelial-mesenchymal transition of human lung adenocarcinoma A549 cells up-regulates cytokine production upon LPS stimulation.	Allergology International	2017
28526654	Clinical and Angiographic Characteristics of 35 Patients With Cryptogenic Hemoptysis.	Chest	2017
27160723	A case of Meigs' syndrome with preceding pericardial effusion in advance of pleural effusion.	BMC Pulmonary Medicine	2016
27180609	Imaging of bacterial multicellular behaviour in biofilms in liquid by atmospheric scanning electron microscopy.	Scientific Reports	2016
26718145	Bronchial artery embolization to control hemoptysis in patients with Mycobacterium avium complex.	Respiratory Investigation	2016
26410549	Evaluation of clinical characteristics and prognosis of chronic pulmonary aspergillosis depending on the underlying lung diseases: Emphysema vs prior tuberculosis.	Journal of Infection and Chemotherapy	2015
26365483	Characteristics of pulmonary Mycobacterium avium complex disease diagnosed later in follow-up after negative mycobacterial study including bronchoscopy.	Respiratory Medicine	2015
24564988	Immuno-electron microscopy of primary cell cultures from genetically modified animals in liquid by atmospheric scanning electron microscopy.	Microscopy and Microanalysis	2014
25130120	Chronic thromboembolic pulmonary hypertension complicated by a cavitating lung infection caused by Mycobacterium intracellulare.	Internal Medicine	2014
23354720	Glucose triggers ATP secretion from bacteria in a growth-phase-dependent manner.	Applied and Environmental Microbiology	2013
24170119	A simple assay for measuring catalase activity: a visual approach.	Scientific Reports	2013
23979748	Effects of bacteriocins on methicillin-resistant Staphylococcus aureus biofilm.	Antimicrobial Agents and Chemotherapy	2013
23316041	Staphylococcus epidermidis Esp degrades specific proteins associated with Staphylococcus aureus biofilm formation and host-pathogen interaction.	Journal of Bacteriology	2013
21904816	Enhanced production of nukacin D13E in Lactococcus lactis NZ9000 by the additional expression of immunity genes.	Applied Microbiology and Biotechnology	2012
22102369	Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding.	Protein Sci	2012