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Author Details

Brendon P Scicluna
Mater Dei Hospital, University of Malta
2009
111
33
PMIDPaper TitleJournal TitlePublished Year
38092143Tracheal epithelial cell-exosome-derived MiR-21-5p inhibits alveolar macrophage pyroptosis to resist pulmonary bacterial infection through PIK3CD-autophagy pathway.Life Sci2024
37496676Inflammatory and glycolytic programs underpin a primed blood neutrophil state in patients with pneumonia.iScience2023
37858304Myeloid miR-155 plays a limited role in antibacterial defense during Klebsiella-derived pneumosepsis and is dispensable for lipopolysaccharide- or Klebsiella-induced inflammation in mice.Pathog Dis2023
37705063High-dimensional analysis reveals an immune atlas and novel neutrophil clusters in the lungs of model animals with Actinobacillus pleuropneumoniae-induced pneumonia.Vet Res2023
34156449Bacterial and Viral Respiratory Tract Microbiota and Host Characteristics in Adults With Lower Respiratory Tract Infections: A Case-Control Study.Clin Infect Dis2022
35405484Myeloid cell tet methylcytosine dioxygenase 2 does not affect the host response during gram-negative bacterial pneumonia and sepsis.Cytokine2022
35717241Effect of intravenous clarithromycin in patients with sepsis, respiratory and multiple organ dysfunction syndrome: a randomized clinical trial.Crit Care2022
35660785The host response in different aetiologies of community-acquired pneumonia.EBioMedicine2022
35938048Rectal microbiota are coupled with altered cytokine production capacity following community-acquired pneumonia hospitalization.iScience2022
36104396Author Correction: Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment.Sci Rep2022
35934940Patients with hypothermic sepsis have a unique gene expression profile compared to patients with fever and sepsis.J Cell Mol Med2022
35903199The Long Non-Coding Antisense RNA JHDM1D-AS1 Regulates Inflammatory Responses in Human Monocytes.Front Cell Infect Microbiol2022
35964875Intracellular pyruvate levels positively correlate with cytokine production capacity in tolerant monocytes from patients with pneumonia.Biochim Biophys Acta Mol Basis Dis2022
35877767Immune suppression is associated with enhanced systemic inflammatory, endothelial and procoagulant responses in critically ill patients.PLoS One2022
35100411Association of Hyperferritinemia With Distinct Host Response Aberrations in Patients With Community-Acquired Pneumonia.J Infect Dis2022
35278745Resolving patient heterogeneity in critical illness requires multi-scale approaches.EBioMedicine2022
35269409DNA Methyltransferase 3b in Myeloid Cells Does Not Affect the Acute Immune Response in the Airways during <i>Pseudomonas</i> Pneumonia.Cells2022
34709498Distinct DNA Methylation Patterns of Subependymal Giant Cell Astrocytomas in Tuberous Sclerosis Complex.Cell Mol Neurobiol2022
34446464Blood leukocyte transcriptomes in Gram-positive and Gram-negative community-acquired pneumonia.Eur Respir J2022
33368438Transcriptional changes in alveolar macrophages from adults with asthma after allergen challenge.Allergy2021
33904193Flagellin induces innate immune genes in bronchial epithelial cells in vivo: Role of TET2.Scand J Immunol2021
33514640Steroid-resistant human inflammatory ILC2s are marked by CD45RO and elevated in type 2 respiratory diseases.Sci Immunol2021
33591001Sepsis Subclasses: A Framework for Development and Interpretation.Crit Care Med2021
33932087Protease-activated receptor 1 drives and maintains ductal cell fates in the premalignant pancreas and ductal adenocarcinoma.Mol Oncol2021
33776992Tenascin-C Deficiency Is Associated With Reduced Bacterial Outgrowth During <i>Klebsiella pneumoniae</i>-Evoked Pneumosepsis in Mice.Front Immunol2021
33913570Alveolar epithelial TET2 is not involved in the development of bleomycin-induced pulmonary fibrosis.FASEB J2021
35011643Role of Myeloid Tet Methylcytosine Dioxygenase 2 in Pulmonary and Peritoneal Inflammation Induced by Lipopolysaccharide and Peritonitis Induced by <i>Escherichia coli</i>.Cells2021
34611613Rectal bacteriome and virome signatures and clinical outcomes in community-acquired pneumonia: An exploratory study.EClinicalMedicine2021
34585271Association between delay in intensive care unit admission and the host response in patients with community-acquired pneumonia.Ann Intensive Care2021
34399830An epigenetic and transcriptomic signature of immune tolerance in human monocytes through multi-omics integration.Genome Med2021
34424199Integrated single-cell analysis unveils diverging immune features of COVID-19, influenza, and other community-acquired pneumonia.Elife2021
34394088The Role of Host Cell DNA Methylation in the Immune Response to Bacterial Infection.Front Immunol2021
34804025HIVEP1 Is a Negative Regulator of NF-κB That Inhibits Systemic Inflammation in Sepsis.Front Immunol2021
34594344Combined Transcriptome and Proteome Leukocyte's Profiling Reveals Up-Regulated Module of Genes/Proteins Related to Low Density Neutrophils and Impaired Transcription and Translation Processes in Clinical Sepsis.Front Immunol2021
34079128Apc-mutant cells act as supercompetitors in intestinal tumour initiation.Nature2021
34272809The circulatory small non-coding RNA landscape in community-acquired pneumonia on intensive care unit admission.J Cell Mol Med2021
33935163Plasma Ferritin as Marker of Macrophage Activation-Like Syndrome in Critically Ill Patients With Community-Acquired Pneumonia.Crit Care Med2021
34319124Tenascin C Has a Modest Protective Effect on Acute Lung Pathology during Methicillin-Resistant Staphylococcus aureus-Induced Pneumonia in Mice.Microbiol Spectr2021
33465019Biological Subphenotypes of Acute Respiratory Distress Syndrome Show Prognostic Enrichment in Mechanically Ventilated Patients without Acute Respiratory Distress Syndrome.Am J Respir Crit Care Med2021
33408258Adherence Affects Monocyte Innate Immune Function and Metabolic Reprogramming after Lipopolysaccharide Stimulation In Vitro.J Immunol2021
31595971Prekallikrein inhibits innate immune signaling in the lung and impairs host defense during pneumosepsis in mice.J Pathol2020
31834371The coding and non-coding transcriptional landscape of subependymal giant cell astrocytomas.Brain2020
33305733The leukocyte non-coding RNA landscape in critically ill patients with sepsis.Elife2020
33329617Corrigendum: Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia.Front Immunol2020
33046509Bronchial Epithelial Tet2 Maintains Epithelial Integrity during Acute Pseudomonas aeruginosa Pneumonia.Infect Immun2020
32604005Elevated trefoil factor 3 plasma levels in critically ill patients with abdominal sepsis or non-infectious abdominal illness.Cytokine2020
32660590The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsis.Crit Care2020
32477337Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia.Front Immunol2020
32472129Dysregulation of the MMP/TIMP Proteolytic System in Subependymal Giant Cell Astrocytomas in Patients With Tuberous Sclerosis Complex: Modulation of MMP by MicroRNA-320d In Vitro.J Neuropathol Exp Neurol2020
32514599Mortality and host response aberrations associated with transient and persistent acute kidney injury in critically ill patients with sepsis: a prospective cohort study.Intensive Care Med2020
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Collaborators

Tom van der Poll
Center for Experimental and Molecular Medicine, University of Amsterdam
Co-authored papers 83
Marcus J Schultz
Amsterdam University Medical Centers
Co-authored papers 36
Lonneke A van Vught
Location University of Amsterdam
Co-authored papers 31
Joris J T H Roelofs
University of Amsterdam
Co-authored papers 7
Johannes A Hainfellner
Medical University of Vienna
Co-authored papers 5
Chiara Caporalini
Co-authored papers 3
Anna Maria Buccoliero
Co-authored papers 3
Lorenzo Genitori
Co-authored papers 3
Wies??awa Grajkowska
Children's Memorial Health Institute
Co-authored papers 3
Julian C Knight
University of Oxford
Co-authored papers 3
Hector R Wong
University of Cincinnati College of Medicine
Co-authored papers 2
John Kenneth Baillie
Roslin Institute, University of Edinburgh
Co-authored papers 2
Peter B Crino
Co-authored papers 2
Louis Vermeulen
Oncode Institute
Co-authored papers 2
Nicole P Juffermans
Erasmus University Medical Center
Co-authored papers 2
Anna C Jansen
Vrije Universiteit Brussel
Co-authored papers 2
Peter Pickkers
Radboud University Medical Centre
Co-authored papers 2
Lieuwe D J Bos
Amsterdam University Medical Centers
Co-authored papers 2
Robert P Dickson
University of Michigan Health System ann arbor
Co-authored papers 1
Dan M Roden
Vanderbilt University Medical Center
Co-authored papers 1
Greg S Martin
Emory University School of Medicine
Co-authored papers 1
Boyd Taylor Thompson
Massachusetts General Hospital, Harvard School of Medicine,
Co-authored papers 1
Adrienne G Randolph
Boston Children's Hospital, Harvard Medical School
Co-authored papers 1
Marie-Jos??e H??bert
Universite de Montreal
Co-authored papers 1
Timothy E Sweeney
Inflammatix Inc.
Co-authored papers 1
David T W Jones
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 1
Vincent X Liu
Kaiser Permanente
Co-authored papers 1
Michiel E Adriaens
Maastricht University
Co-authored papers 1
Annette M Esper
Atlanta Center for Microsystems Engineered Point-of-Care Technologies.
Co-authored papers 1
Jason N Kennedy
Clinical Research
Co-authored papers 1
Release 1.2