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Author Details
Full Name
Holger S??ltmann
Affiliation
German Cancer Research Center (DKFZ)
ORCID
Career Start Year
1993
Papers
164
H Index
47
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37152238
An artificial intelligence-based chatbot for prostate cancer education: Design and patient evaluation study.
Digit Health
2023
34325986
Mutations in TP53 or DNA damage repair genes define poor prognostic subgroups in primary prostate cancer.
Urol Oncol
2022
36551580
Biomarkers for the Detection and Risk Stratification of Aggressive Prostate Cancer.
Cancers (Basel)
2022
36461127
Longitudinal monitoring of cell-free DNA methylation in ALK-positive non-small cell lung cancer patients.
Clin Epigenetics
2022
36387148
Serum cytokines predict efficacy and toxicity, but are not useful for disease monitoring in lung cancer treated with PD-(L)1 inhibitors.
Front Oncol
2022
35205634
Impact of Surgeon's Experience in Rigid versus Elastic MRI/TRUS-Fusion Biopsy to Detect Significant Prostate Cancer Using Targeted and Systematic Cores.
Cancers (Basel)
2022
35202954
Recommendations for a practical implementation of circulating tumor DNA mutation testing in metastatic non-small-cell lung cancer.
ESMO Open
2022
34164264
Earlier extracranial progression and shorter survival in ALK-rearranged lung cancer with positive liquid rebiopsies.
Transl Lung Cancer Res
2021
33686791
KRAS/GNAS-testing by highly sensitive deep targeted next generation sequencing improves the endoscopic ultrasound-guided workup of suspected mucinous neoplasms of the pancreas.
Genes Chromosomes Cancer
2021
33485866
DNA Promoter Methylation and ERG Regulate the Expression of CD24 in Prostate Cancer.
Am J Pathol
2021
33669024
<i>miR-449a</i> Repression Leads to Enhanced NOTCH Signaling in <i>TMPRSS2:ERG</i> Fusion Positive Prostate Cancer Cells.
Cancers (Basel)
2021
34876698
Early identification of disease progression in ALK-rearranged lung cancer using circulating tumor DNA analysis.
NPJ Precis Oncol
2021
34830770
Liquid Biopsies beyond Mutation Calling: Genomic and Epigenomic Features of Cell-Free DNA in Cancer.
Cancers (Basel)
2021
33959513
Feasibility and Challenges for Sequential Treatments in ALK-Rearranged Non-Small-Cell Lung Cancer.
Front Oncol
2021
31605236
Circulating MicroRNAs as Potential Biomarkers for Lung Cancer.
Recent Results Cancer Res
2020
32051394
Correction: Excess hepsin proteolytic activity limits oncogenic signaling and induces ER stress and autophagy in prostate cancer cells.
Cell Death Dis
2020
33161228
Longitudinal therapy monitoring of ALK-positive lung cancer by combined copy number and targeted mutation profiling of cell-free DNA.
EBioMedicine
2020
32674955
Rearranged ERG confers robustness to prostate cancer cells by subverting the function of p53.
Urol Oncol
2020
32646965
The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ε-FOXO Pathway.
Mol Cancer Res
2020
32280037
High prevalence of DNA damage repair gene defects and TP53 alterations in men with treatment-naïve metastatic prostate cancer -Results from a prospective pilot study using a 37 gene panel.
Urol Oncol
2020
32272161
Genome-Wide DNA Methylation Profiling in Early Stage I Lung Adenocarcinoma Reveals Predictive Aberrant Methylation in the Promoter Region of the Long Noncoding RNA PLUT: An Exploratory Study.
J Thorac Oncol
2020
32290637
Novel Liquid Biomarker Panels for A Very Early Response Capturing of NSCLC Therapies in Advanced Stages.
Cancers (Basel)
2020
30535430
Pathways regulating the expression of the immunomodulatory protein glycodelin in nonâ¿¿small cell lung cancer.
Int J Oncol
2019
30216696
Digital PCR After MALDI-Mass Spectrometry Imaging to Combine Proteomic Mapping and Identification of Activating Mutations in Pulmonary Adenocarcinoma.
Proteomics Clin Appl
2019
30230086
Next generation sequencing of the cellular and liquid fraction of pancreatic cyst fluid supports discrimination of IPMN from pseudocysts and reveals cases with multiple mutated driver clones: First findings from the prospective ZYSTEUS biomarker study.
Genes Chromosomes Cancer
2019
31549213
The BRCA2 mutation status shapes the immune phenotype of prostate cancer.
Cancer Immunol Immunother
2019
31139322
Defining molecular risk in ALK<sup>+</sup> NSCLC.
Oncotarget
2019
30899423
Multiple layers of intratumor heterogeneity: clues to clonal evolution of non-small cell lung cancer.
Oncotarget
2019
30350867
Global DNA methylation reflects spatial heterogeneity and molecular evolution of lung adenocarcinomas.
Int J Cancer
2019
30669647
Detection of TP53 Mutations in Tissue or Liquid Rebiopsies at Progression Identifies ALK+ Lung Cancer Patients with Poor Survival.
Cancers (Basel)
2019
29198908
Overexpression of nuclear AR-V7 protein in primary prostate cancer is an independent negative prognostic marker in men with high-risk disease receiving adjuvant therapy.
Urol Oncol
2018
30029672
Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance.
Genome Med
2018
29887238
FGF-2 is a driving force for chromosomal instability and a stromal factor associated with adverse clinico-pathological features in prostate cancer.
Urol Oncol
2018
30200539
Genome-Based Classification and Therapy of Prostate Cancer.
Diagnostics (Basel)
2018
30352093
Molecular signatures in IASLC/ATS/ERS classified growth patterns of lung adenocarcinoma.
PLoS One
2018
30420756
Correlation between genomic index lesions and mpMRI and <sup>68</sup>Ga-PSMA-PET/CT imaging features in primary prostate cancer.
Sci Rep
2018
30537516
Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories.
Cancer Cell
2018
28379479
Experimental design and data analysis of Ago-RIP-Seq experiments for the identification of microRNA targets.
Brief Bioinform
2018
29524530
Hepatitis D virus replication is sensed by MDA5 and induces IFN-β/λ responses in hepatocytes.
J Hepatol
2018
29748622
Genomic features of renal cell carcinoma with venous tumor thrombus.
Sci Rep
2018
29796302
Prospective single center trial of next-generation sequencing analysis in metastatic renal cell cancer: the MORE-TRIAL.
Future Sci OA
2018
29086374
Identification of E6/E7-Dependent MicroRNAs in HPV-Positive Cancer Cells.
Methods Mol Biol
2018
29205637
A field guide for cancer diagnostics using cell-free DNA: From principles to practice and clinical applications.
Genes Chromosomes Cancer
2018
27913729
QSEA-modelling of genome-wide DNA methylation from sequencing enrichment experiments.
Nucleic Acids Res
2017
28445989
TMPRSS2:ERG gene fusion variants induce TGF-β signaling and epithelial to mesenchymal transition in human prostate cancer cells.
Oncotarget
2017
29088767
Patient-specific molecular alterations are associated with metastatic clear cell renal cell cancer progressing under tyrosine kinase inhibitor therapy.
Oncotarget
2017
28676659
Mutations in BRCA2 and taxane resistance in prostate cancer.
Sci Rep
2017
28699162
Spatial distribution of EGFR and KRAS mutation frequencies correlates with histological growth patterns of lung adenocarcinomas.
Int J Cancer
2017
27687312
PARP inhibition in BRCA2-mutated prostate cancer.
Ann Oncol
2017
27279498
Cross-talk between AMPK and EGFR dependent Signaling in Non-Small Cell Lung Cancer.
Sci Rep
2016
1 - 50 of 164
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Washington University School of Medicine
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Karolinska Institute
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Charite - University Hospital Berlin
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Anna-Lena Volckmar
Institut fur Pathologie, Universitatsklinikum Heidelberg
Co-authored papers
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Institute of Pathology, University Hospital Heidelberg
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Guido Sauter
Institute of Pathology, University Medical Center Hamburg-Eppendorf
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Daniel Kazdal
Institut fur Pathologie, Universitatsklinikum Heidelberg
Co-authored papers
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Peter Schirmacher
Institute of Pathology, University Hospital Heidelberg
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9
Wolfgang Huber
Technische Universitat Munchen
Co-authored papers
8
Michal R Schweiger
Institute for Translational Epigenetics, University of Cologne
Co-authored papers
8
Holger Fr??hlich
Bonn-Aachen International Center for IT (B-IT), University of Bonn
Co-authored papers
8
Matthias Schlesner
University of Augsburg
Co-authored papers
7
Ronald Simon
Institute of Pathology, University Medical Center Hamburg-Eppendorf
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Stefan Wiemann
Co-authored papers
6
Markus Graefen
University Hospital Frankfurt, Goethe University Frankfurt am Main
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6
Martina Kirchner
Institute of Pathology, University Hospital Heidelberg
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Hartwig Huland
Martini-Klinik Prostate Cancer Center, University Hospital-Hamburg-Eppendorf
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Marie-Laure Yaspo
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Roland Eils
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