Author details

Full Name

Michael J O Wakelam

Affiliation

ORCID

Career Start Year

1979

Papers

242

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36652341	Comprehensive lipidome of human plasma using minimal sample manipulation by liquid chromatography coupled with mass spectrometry.		2023
36291074	The Effect of a Mutation on Hearing and Lipid Content of the Inner Ear.	Cells	2022
34362906	Quality control requirements for the correct annotation of lipidomics data.	Nat Commun	2021
33909989	Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine.	Molecular Cell	2021
34168259	Integrated lipidomics and proteomics reveal cardiolipin alterations, upregulation of HADHA and long chain fatty acids in pancreatic cancer stem cells.	Scientific Reports	2021
34723964	Neuronal HSF-1 coordinates the propagation of fat desaturation across tissues to enable adaptation to high temperatures in C. elegans.	PLoS Biology	2021
33215159	Potential Role of Oral Rinses Targeting the Viral Lipid Envelope in SARS-CoV-2 Infection.		2020
31646749	Lipidomics: Current state of the art in a fast moving field.	Wiley Interdisciplinary Reviews: Systems Biology and Medicine	2020
31942031	MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer.	Br J Cancer	2020
32437392	THP-1 macrophage cholesterol efflux is impaired by palmitoleate through Akt activation.	PLoS ONE	2020
33037133	Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures.	J Lipid Res	2020
33196315	Steps Toward Minimal Reporting Standards for Lipidomics Mass Spectrometry in Biomedical Research Publications.	Circ Genom Precis Med	2020
30670689	The circadian clock components BMAL1 and REV-ERBÎ± regulate flavivirus replication.	Nat Commun	2019
31742247	A nutritional memory effect counteracts benefits of dietary restriction in old mice.	Nat Metab	2019
30478149	3D Growth of Cancer Cells Elicits Sensitivity to Kinase Inhibitors but Not Lipid Metabolism Modifiers.	Mol Cancer Ther	2019
30622195	LIPID MAPS: Serving the next generation of lipid researchers with tools, resources, data, and training.	Sci Signal	2019
29787576	Flotillin proteins recruit sphingosine to membranes and maintain cellular sphingosine-1-phosphate levels.	PLoS ONE	2018
30115755	MS-based lipidomics of human blood plasma: a community-initiated position paper to develop accepted guidelines.	J Lipid Res	2018
30352178	C.Â elegans Eats Its Own Intestine to Make Yolk Leading to Multiple Senescent Pathologies.	Current Biology	2018
30257985	CD151 regulates expression of FGFR2 in breast cancer cells via PKC-dependent pathways.	Journal of Cell Science	2018
30488036	Modeling Meets Metabolomics-The WormJam Consensus Model as Basis for Metabolic Studies in the Model Organism <i>Caenorhabditis elegans</i>.	Front Mol Biosci	2018
30100339	C.Â elegans Eats Its Own Intestine to Make Yolk Leading to Multiple Senescent Pathologies.	Current Biology	2018
29946055	Host lipidome analysis during rhinovirus replication in HBECs identifies potential therapeutic targets.	J Lipid Res	2018
29764923	Extracellular vesicles: lipids as key components of their biogenesis and functions.	Journal of Lipid Research	2018
29683435	Phospholipid signaling in innate immune cells.	Journal of Clinical Investigation	2018
27816901	Using lipidomics analysis to determine signalling and metabolic changes in cells.	Current Opinion in Biotechnology	2017
28351387	Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism.	Genome Biol	2017
29058722	Deciphering lipid structures based on platform-independent decision rules.	Nature Methods	2017
28126468	Autotaxin-lysophosphatidic acid receptor signalling regulates hepatitis C virus replication.	J Hepatol	2017
27869314	Runx1 Orchestrates Sphingolipid Metabolism and Glucocorticoid Resistance in Lymphomagenesis.	Journal of Cellular Biochemistry	2017
27557622	Exosomes bind to autotaxin and act as a physiological delivery mechanism to stimulate LPA receptor signalling in cells.	Journal of Cell Science	2016
25408419	The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer.	Molecular Carcinogenesis	2016
27042297	Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments.	Cancer Metab	2016
27478939	C13orf31 (FAMIN) is a central regulator of immunometabolic function.	Nat Immunol	2016
26302980	Phosphatidylinositolphosphate phosphatase activities and cancer.	Journal of Lipid Research	2016
27766312	Insulin resistance uncoupled from dyslipidemia due to C-terminal PIK3R1 mutations.	JCI Insight	2016
27658289	The Phospholipase D2 Knock Out Mouse Has Ectopic Purkinje Cells and Suffers from Early Adult-Onset Anosmia.	PLoS ONE	2016
27848911	Phospholipase D activity couples plasma membrane endocytosis with retromer dependent recycling.	eLife	2016
26333836	Cell cycle progression is an essential regulatory component of phospholipid metabolism and membrane homeostasis.	Open Biology	2015
25584894	Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress.	Cancer Cell	2015
25538043	P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.	Blood	2015
25673862	Speed and sensitivity of phototransduction in Drosophila depend on degree of saturation of membrane phospholipids.	Journal of Neuroscience	2015
26312899	Phosphoinositide 3-kinase-related overgrowth: cellular phenotype and future therapeutic options.	Lancet, The	2015
26423580	Purification, characterization and crystallization of the F-ATPase from Paracoccus denitrificans.	Open Biology	2015
24917668	Modulation of triglyceride and cholesterol ester synthesis impairs assembly of infectious hepatitis C virus.	Journal of Biological Chemistry	2014
25313567	Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal.	PLoS Biology	2014
25263561	Fatty acid uptake and lipid storage induced by HIF-1Î± contribute to cell growth and survival after hypoxia-reoxygenation.	Cell Rep	2014
24439389	SnapShot: Lipid kinase and phosphatase reaction pathways.	Cell	2014
24332194	Lipidomics in the analysis of malignancy.	Advances in Biological Regulation	2014
24769341	The uses and limitations of the analysis of cellular phosphoinositides by lipidomic and imaging methodologies.		2014