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Author Details

Andrew R Leach
European Bioinformatics Institute (EMBL-EBI)
1987
64
29
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37933841The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods.Nucleic Acids Res2024
37933841The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods.Nucleic Acids Res2024
36477213EMBL's European Bioinformatics Institute (EMBL-EBI) in 2022.Nucleic Acids Res2023
37944397Editorial overview: Restructuring drug design and development.Curr Opin Struct Biol2023
37749083Integrative GWAS and co-localisation analysis suggests novel genes associated with age-related multimorbidity.Sci Data2023
37151295Illuminating the druggable genome through patent bioactivity data.PeerJ2023
37316648eTRANSAFE: data science to empower translational safety assessment.Nat Rev Drug Discov2023
36477213EMBL's European Bioinformatics Institute (EMBL-EBI) in 2022.Nucleic Acids Res2023
37117846Applications of single-cell RNA sequencing in drug discovery and development.Nat Rev Drug Discov2023
37429843Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure.Nat Commun2023
37749083Integrative GWAS and co-localisation analysis suggests novel genes associated with age-related multimorbidity.Sci Data2023
37944397Editorial overview: Restructuring drug design and development.Curr Opin Struct Biol2023
37316648eTRANSAFE: data science to empower translational safety assessment.Nat Rev Drug Discov2023
37151295Illuminating the druggable genome through patent bioactivity data.PeerJ2023
37117846Applications of single-cell RNA sequencing in drug discovery and development.Nat Rev Drug Discov2023
37429843Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure.Nat Commun2023
34437766The Enzyme Portal: an integrative tool for enzyme information and analysis.FEBS J2022
35783295CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding.Nat Rev Chem2022
34437766The Enzyme Portal: an integrative tool for enzyme information and analysis.FEBS J2022
35783295CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding.Nat Rev Chem2022
34285415The PROTACtable genome.Nat Rev Drug Discov2021
34285415The PROTACtable genome.Nat Rev Drug Discov2021
33837377Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19.Nat Med2021
33618772MAIP: a web service for predicting blood-stage malaria inhibitors.J Cheminform2021
33507738Drug Safety Data Curation and Modeling in ChEMBL: Boxed Warnings and Withdrawn Drugs.Chem Res Toxicol2021
33983732Target-Based Evaluation of "Drug-Like" Properties and Ligand Efficiencies.J Med Chem2021
34349756Influence of HLA Class II Polymorphism on Predicted Cellular Immunity Against SARS-CoV-2 at the Population and Individual Level.Front Immunol2021
35211674Target 2035 - update on the quest for a probe for every protein.RSC Med Chem2021
33618772MAIP: a web service for predicting blood-stage malaria inhibitors.J Cheminform2021
33507738Drug Safety Data Curation and Modeling in ChEMBL: Boxed Warnings and Withdrawn Drugs.Chem Res Toxicol2021
33837377Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19.Nat Med2021
35211674Target 2035 - update on the quest for a probe for every protein.RSC Med Chem2021
34349756Influence of HLA Class II Polymorphism on Predicted Cellular Immunity Against SARS-CoV-2 at the Population and Individual Level.Front Immunol2021
33983732Target-Based Evaluation of "Drug-Like" Properties and Ligand Efficiencies.J Med Chem2021
32207937Hotspots API: A Python Package for the Detection of Small Molecule Binding Hotspots and Application to Structure-Based Drug Design.J Chem Inf Model2020
32207937Hotspots API: A Python Package for the Detection of Small Molecule Binding Hotspots and Application to Structure-Based Drug Design.J Chem Inf Model2020
32645325The Global Phosphorylation Landscape of SARS-CoV-2 Infection.Cell2020
32627965Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens.Mol Syst Biol2020
32627965Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens.Mol Syst Biol2020
32645325The Global Phosphorylation Landscape of SARS-CoV-2 Infection.Cell2020
30398643ChEMBL: towards direct deposition of bioassay data.Nucleic Acids Res2019
33430932Reply to "Missed opportunities in large scale comparison of QSAR and conformal prediction methods and their applications in drug discovery".J Cheminform2019
30398643ChEMBL: towards direct deposition of bioassay data.Nucleic Acids Res2019
30631996Large scale comparison of QSAR and conformal prediction methods and their applications in drug discovery.J Cheminform2019
33430932Reply to "Missed opportunities in large scale comparison of QSAR and conformal prediction methods and their applications in drug discovery".J Cheminform2019
30631996Large scale comparison of QSAR and conformal prediction methods and their applications in drug discovery.J Cheminform2019
29276046Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions.Cell Chem Biol2018
30351302A large-scale dataset of in vivo pharmacology assay results.Sci Data2018
29567993Unexplored therapeutic opportunities in the human genome.Nat Rev Drug Discov2018
29472638Unexplored therapeutic opportunities in the human genome.Nat Rev Drug Discov2018
  • 1 - 50 of 128

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Collaborators

Anna Gaulton
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 14
Anne Hersey
Co-authored papers 11
Eloy Felix
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 8
Tudor I Oprea
Expert Systems Inc.
Co-authored papers 4
John P Overington
Institute of Cardiovascular Science, University College London
Co-authored papers 4
S??ren Brunak
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
Co-authored papers 3
Anton Simeonov
Co-authored papers 3
George Papadatos
European Molecular Biology Laboratory - European Bioinformatics Institute
Co-authored papers 3
Brian K Shoichet
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 3
Cristian G Bologa
University of New Mexico School of Medicine
Co-authored papers 3
Gregory N Gan
Co-authored papers 2
Gergely Zahoránszky-Kſhalmi
Co-authored papers 2
Jun Qin
Co-authored papers 2
Sandra Orchard
EMBL's European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 2
Christian Reich
Co-authored papers 2
John Michael Gaziano
VA Boston Healthcare System
Co-authored papers 2
Noel Southall
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 2
Juan P Casas
Co-authored papers 2
Suzanne Ackloo
University of Toronto
Co-authored papers 2
Ajit Jadhav
Co-authored papers 2
Jayme Holmes
Co-authored papers 2
Avi Ma'ayan
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Stephan C Sch??rer
Institute for Data Science and Computing, University of Miami
Co-authored papers 2
Oleg Ursu
Co-authored papers 2
Susumu Tomita
Co-authored papers 2
Jennifer E Huffman
Co-authored papers 2
Anneli Karlson
Co-authored papers 2
Dac-Trung Nguyen
Co-authored papers 2
Anna Waller
Co-authored papers 2
Terrence F Meehan
European Bioinformatics Institute
Co-authored papers 2
Release 1.2