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Author Details

Jonathan Schug
University of Pennsylvania Perelman School of Medicine
1997
95
47
PMIDPaper TitleJournal TitlePublished Year
36869037Mu-opioid receptor-expressing neurons in the paraventricular thalamus modulate chronic morphine-induced wake alterations.Transl Psychiatry2023
37188822Single-cell expression profiling of islets generated by the Human Pancreas Analysis Program.Nat Metab2023
37037491Advanced precision modeling reveals divergent responses of hepatocellular carcinoma to combinatorial immunotherapy.Cancer Commun (Lond)2023
36711819Computational workflow and interactive analysis of single-cell expression profiling of islets generated by the Human Pancreas Analysis Program.bioRxiv2023
34352401Evaluating whole-genome expression differences in idiopathic and diabetic adhesive capsulitis.J Shoulder Elbow Surg2022
34563123CAMPAREE: a robust and configurable RNA expression simulator.BMC Genomics2021
33621209Highly multiplexed 2-dimensional imaging mass cytometry analysis of HBV-infected liver.JCI Insight2021
33636105FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity.Dev Cell2021
35008427Paternal Exercise Improves the Metabolic Health of Offspring via Epigenetic Modulation of the Germline.Int J Mol Sci2021
34529988Highly Multiplexed Image Analysis of Intestinal Tissue Sections in Patients With Inflammatory Bowel Disease.Gastroenterology2021
32739450Single-cell transcriptomics of human islet ontogeny defines the molecular basis of β-cell dedifferentiation in T2D.Mol Metab2020
31759059A High-Content Screen Identifies MicroRNAs That Regulate Liver Repopulation After Injury in Mice.Gastroenterology2020
32631996A negative reciprocal regulatory axis between cyclin D1 and HNF4α modulates cell cycle progression and metabolism in the liver.Proc Natl Acad Sci U S A2020
30713110Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes.Cell Metab2019
31836704miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes.Nat Commun2019
31888770APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain.Alzheimers Res Ther2019
31530843Comparative evaluation of RNA-Seq library preparation methods for strand-specificity and low input.Sci Rep2019
29298866A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes.Sci Transl Med2018
30293786Genome-wide Identification of Structure-Forming Repeats as Principal Sites of Fork Collapse upon ATR Inhibition.Mol Cell2018
29475831Sleeve Gastrectomy Improves Glycemia Independent of Weight Loss by Restoring Hepatic Insulin Sensitivity.Diabetes2018
29402210Defiant: (DMRs: easy, fast, identification and ANnoTation) identifies differentially Methylated regions from iron-deficient rat hippocampus.BMC Bioinformatics2018
29038051Integrated approach reveals diet, APOE genotype and sex affect immune response in APP mice.Biochim Biophys Acta Mol Basis Dis2018
28655926Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer's model mice.Sci Rep2017
28502803Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury.Neurobiol Dis2017
28442472Functional and Metabolomic Consequences of K<sub>ATP</sub> Channel Inactivation in Human Islets.Diabetes2017
28813430Reprogramming human gallbladder cells into insulin-producing β-like cells.PLoS One2017
28797240A comparison of Illumina and Ion Torrent sequencing platforms in the context of differential gene expression.BMC Genomics2017
26721486ChIP-Seq: Library Preparation and Sequencing.Methods Mol Biol2016
27732837Single-Cell Mass Cytometry Analysis of the Human Endocrine Pancreas.Cell Metab2016
27364731Single-Cell Transcriptomics of the Human Endocrine Pancreas.Diabetes2016
27393338The next generation of target capture technologies - large DNA fragment enrichment and sequencing determines regional genomic variation of high complexity.BMC Genomics2016
27399229Human islets contain four distinct subtypes of β cells.Nat Commun2016
26977395Integration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genes.Mol Metab2016
27051978RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers.Sci Rep2016
25768493Penetration depth scaling for impact into wet granular packings.Phys Rev E Stat Nonlin Soft Matter Phys2015
26321660Aging-Dependent Demethylation of Regulatory Elements Correlates with Chromatin State and Improved β Cell Function.Cell Metab2015
26311769Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity.J Neurosci2015
26071899RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment.Neurobiol Dis2015
26023099Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium.Development2015
24269917Genome-wide approaches reveal EGR1-controlled regulatory networks associated with neurodegeneration.Neurobiol Dis2014
25469308Two novel type 2 diabetes loci revealed through integration of TCF7L2 DNA occupancy and SNP association data.BMJ Open Diabetes Res Care2014
25369933Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia.Proc Natl Acad Sci U S A2014
25028525Islet-1 Is essential for pancreatic β-cell function.Diabetes2014
25073103Activated FoxM1 attenuates streptozotocin-mediated β-cell death.Mol Endocrinol2014
25151611The organoid-initiating cells in mouse pancreas and liver are phenotypically and functionally similar.Stem Cell Res2014
24878043Genome-wide analyses of ChIP-Seq derived FOXA2 DNA occupancy in liver points to genetic networks underpinning multiple complex traits.J Clin Endocrinol Metab2014
24637118DNA methylation is required for the control of stem cell differentiation in the small intestine.Genes Dev2014
24374217Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets.Cell Metab2014
23318056Dynamic chromatin remodeling mediated by polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells.Cell Stem Cell2013
23959892Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal-Hreidarsson syndrome.Proc Natl Acad Sci U S A2013
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Collaborators

Klaus H Kaestner
Department of Genetics and Institute for Diabetes, University of Pennsylvania
Co-authored papers 54
Christian J Stoeckert
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 12
Gregory R Grant
Perelman School of Medicine, University of Pennsylvania Philadelphia
Co-authored papers 8
Jonathan Crabtree
Institute for Genome Sciences, University of Maryland School of Medicine
Co-authored papers 7
Brian P Brunk
University of Pennsylvania
Co-authored papers 7
Peter White
The Ohio State University
Co-authored papers 5
Elisabetta Manduchi
Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia
Co-authored papers 5
David S Roos
University of Pennsylvania
Co-authored papers 4
Kyoung-Jae Won
Co-authored papers 4
Jessica C Kissinger
University of Georgia
Co-authored papers 4
Nicholas F Lahens
University of Pennsylvania.
Co-authored papers 4
Kyong-Mi Chang
Corporal Michael J Crescenz VA Medical Center
Co-authored papers 3
Li Li
Center for Bioinformatics, University of Pennsylvania
Co-authored papers 3
Vasumathi Kameswaran
Gladstone Institutes
Co-authored papers 3
Amit Bahl
University Hospitals Bristol and Weston NHS Foundation Trust
Co-authored papers 3
Mark Gibson
Co-authored papers 3
Arthur J Milgram
Co-authored papers 3
Struan F A Grant
Center for Spatial and Functional Genomics, The Children's Hospital of Philadelphia
Co-authored papers 3
Dinesh Gupta
International Centre for Genetic Engineering and Biotechnology (ICGEB)
Co-authored papers 3
Philip Labo
Co-authored papers 3
Sharon J Diskin
Children's Hospital of Philadelphia
Co-authored papers 3
Martin Fraunholz
Julius-Maximilians-Universitat Wurzburg
Co-authored papers 3
Angel Pizarro
The Institute for Translational Medicine and Therapeutics, University of Pennsylvania
Co-authored papers 2
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 2
Bradley E Bernstein
Broad Institute of MIT and Harvard
Co-authored papers 2
Dyann F Wirth
The Broad Institute
Co-authored papers 2
Joan Mazzarelli
Center for Bioinformatics, University of Pennsylvania
Co-authored papers 2
Hagai Ginsburg
The Alexander Silberman Institute of Life Science, Hebrew University of Jerusalem
Co-authored papers 2
Leonard Charles Bailey
Children's Hospital of Philadelphia
Co-authored papers 2
Matthew E Johnson
Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia
Co-authored papers 2
Release 1.2