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Author Details

William McGinnis
University of California
1980
102
55
PMIDPaper TitleJournal TitlePublished Year
34791161High-resolution in situ analysis of Cas9 germline transcript distributions in gene-drive Anopheles mosquitoes.G3 (Bethesda)2022
34791185The expression of Drosophila melanogaster Hox gene Ultrabithorax is not overtly regulated by the intronic long noncoding RNA lncRNA:PS4 in a wild-type genetic background.G3 (Bethesda)2022
34757777Dissecting the evolutionary role of the <i>Hox</i> gene <i>proboscipedia</i> in <i>Drosophila</i> mouthpart diversification by full locus replacement.Sci Adv2021
28787415Rules of the road for insect gene drive research and testing.Nat Biotechnol2017
28289197Toll pathway is required for wound-induced expression of barrier repair genes in the <i>Drosophila</i> epidermis.Proc Natl Acad Sci U S A2017
23637905Serine proteolytic pathway activation reveals an expanded ensemble of wound response genes in Drosophila.PLoS One2013
24300796Microinjection wound assay and in vivo localization of epidermal wound response reporters in Drosophila embryos.J Vis Exp2013
22393361Three Drosophila Hox complex microRNAs do not have major effects on expression of evolutionarily conserved Hox gene targets during embryogenesis.PLoS One2012
22590528The functions of grainy head-like proteins in animals and fungi and the evolution of apical extracellular barriers.PLoS One2012
21187384Phosphorylation of Grainy head by ERK is essential for wound-dependent regeneration but not for development of an epidermal barrier.Proc Natl Acad Sci U S A2011
22242003Duox, Flotillin-2, and Src42A are required to activate or delimit the spread of the transcriptional response to epidermal wounds in Drosophila.PLoS Genet2011
21920356Gene length may contribute to graded transcriptional responses in the Drosophila embryo.Dev Biol2011
20433454Silencing of an abdominal Hox gene during early development is correlated with limb development in a crustacean trunk.Evol Dev2010
20164092Minimizing off-target signals in RNA fluorescent in situ hybridization.Nucleic Acids Res2010
20435033Co-option of an anteroposterior head axis patterning system for proximodistal patterning of appendages in early bilaterian evolution.Dev Biol2010
19168633Multiple transcription factor codes activate epidermal wound-response genes in Drosophila.Proc Natl Acad Sci U S A2009
19931455Visualization of individual Scr mRNAs during Drosophila embryogenesis yields evidence for transcriptional bursting.Curr Biol2009
18273011The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans.Nature2008
18504607Context-dependent regulation of Hox protein functions by CK2 phosphorylation sites.Dev Genes Evol2008
16901778Gap peptides: A new way to control embryonic patterning?Cell2006
17008523Genomic evolution of Hox gene clusters.Science2006
15979302Pattern formation and developmental mechanisms: good mileage from comparative studies in cell biology, gene regulation, development and evolution.Curr Opin Genet Dev2005
16341070Modulating Hox gene functions during animal body patterning.Nat Rev Genet2005
16284118Evolutionarily conserved domains required for activation and repression functions of the Drosophila Hox protein Ultrabithorax.Development2005
15831751An epidermal barrier wound repair pathway in Drosophila is mediated by grainy head.Science2005
15864850Bill McGinnis.Curr Biol2005
15297669Multiplex detection of RNA expression in Drosophila embryos.Science2004
12672498Evolution of transcription factor function.Curr Opin Genet Dev2003
11857506Complete mutation analysis panel of the 39 human HOX genes.Teratology2002
12204260Structure and expression patterns of Drosophila TULP and TUSP, members of the tubby-like gene family.Mech Dev2002
12202035The Drosophila Hox gene deformed sculpts head morphology via direct regulation of the apoptosis activator reaper.Cell2002
12176372Hox Genes: it's all a matter of context.Curr Biol2002
12112874DEAF-1 function is essential for the early embryonic development of Drosophila.Genesis2002
11859370Hox protein mutation and macroevolution of the insect body plan.Nature2002
10720435Developmental patterning genes and their conserved functions: from model organisms to humans.Mol Genet Metab2000
10952900Cap 'n' collar B cooperates with a small Maf subunit to specify pharyngeal development and suppress deformed homeotic function in the Drosophila head.Development2000
10940637Homeobrain, a novel paired-like homeobox gene is expressed in the Drosophila brain.Mech Dev2000
11014815Regulation by homeoproteins: a comparison of deformed-responsive elements.Genetics2000
10556062spen encodes an RNP motif protein that interacts with Hox pathways to repress the development of head-like sclerites in the Drosophila trunk.Development1999
10364522Monodactylous limbs and abnormal genitalia are associated with hemizygosity for the human 2q31 region that includes the HOXD cluster.Am J Hum Genet1999
10359793Activity regulation of Hox proteins, a mechanism for altering functional specificity in development and evolution.Proc Natl Acad Sci U S A1999
9878063Activity regulation of a Hox protein and a role for the homeodomain in inhibiting transcriptional activation.EMBO J1999
10101132Hox genes differentially regulate Serrate to generate segment-specific structures.Development1999
10572035A sequence motif distinct from Hox binding sites controls the specificity of a Hox response element.Development1999
9778513A cap 'n' collar protein isoform contains a selective Hox repressor function.Development1998
9631657Shaping animal body plans in development and evolution by modulation of Hox expression patterns.Bioessays1998
9832527A genetic screen of the Drosophila X chromosome for mutations that modify Deformed function.Genetics1998
9310327A genetic screen for modifiers of Deformed homeotic function identifies novel genes required for head development.Development1997
9155029A model for extradenticle function as a switch that changes HOX proteins from repressors to activators.EMBO J1997
9415690Prader-Willi and Angelman syndromes: diagnosis with a bisulfite-treated methylation-specific PCR method.Am J Med Genet1997
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Collaborators

Co-authored papers 12
Co-authored papers 7
University of California
Co-authored papers 5
University of California irvine
Co-authored papers 2
Center for Medical Genetics, Keio University School of Medicine
Co-authored papers 2
University of California san francisco
Co-authored papers 1
University of California San Diego
Co-authored papers 1
University of California
Co-authored papers 1
J. Craig Venter Institute
Co-authored papers 1
Co-authored papers 1
Massachusetts Institute of Technology
Co-authored papers 1
Institut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra)
Co-authored papers 1
University of Wurzburg
Co-authored papers 1
Center for Computational Biology & Bioinformatics (CCBB), University of California
Co-authored papers 1
University of California
Co-authored papers 1
Northumberland Tyne and Wear NHS Foundation Trust, St Nicholas Hospital
Co-authored papers 1
The University of Adelaide Faculty of Health and Medical Sciences
Co-authored papers 1
Texas A&M University, College Station
Co-authored papers 1
National Institutes of Health
Co-authored papers 1
Research Ethics Program, 4University of California
Co-authored papers 1
Western Michigan University
Co-authored papers 1
Co-authored papers 1
University of Tennessee Health Science Center
Co-authored papers 1
Innovative Genomics Institute
Co-authored papers 1
Research Ethics Program, University of California
Co-authored papers 1
Yale University School of Medicine
Co-authored papers 1
Legler Benbough Foundation
Co-authored papers 1
National Institutes of Health
Co-authored papers 1
Co-authored papers 1
National Institutes of Health
Co-authored papers 1