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Author Details

Elaine C Meng
Department of Pharmaceutical Chemistry, University of California San Francisco
1990
36
29
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36759942The scalable precision medicine open knowledge engine (SPOKE): a massive knowledge graph of biomedical information.Bioinformatics2023
32881101UCSF ChimeraX: Structure visualization for researchers, educators, and developers.Protein Sci2021
34912541scNetViz: from single cells to networks using Cytoscape.F1000Res2021
28710774UCSF ChimeraX: Meeting modern challenges in visualization and analysis.Protein Sci2018
29964044Molecular Visualization on the Holodeck.J Mol Biol2018
30097089Atlas of the Radical SAM Superfamily: Divergent Evolution of Function Using a "Plug and Play" Domain.Methods Enzymol2018
28605775Biocuration in the structure-function linkage database: the anatomy of a superfamily.Database (Oxford)2017
28365730Biocuration in the structure-function linkage database: the anatomy of a superfamily.Database (Oxford)2017
24271399The Structure-Function Linkage Database.Nucleic Acids Res2014
24861624Enhancing UCSF Chimera through web services.Nucleic Acids Res2014
21963794UCSF Chimera, MODELLER, and IMP: an integrated modeling system.J Struct Biol2012
21097780ModBase, a database of annotated comparative protein structure models, and associated resources.Nucleic Acids Res2011
21458983Topological variation in the evolution of new reactions in functionally diverse enzyme superfamilies.Curr Opin Struct Biol2011
20525940Computational tools for the interactive exploration of proteomic and structural data.Mol Cell Proteomics2010
19369428DOCK 6: combining techniques to model RNA-small molecule complexes.RNA2009
17658942Evolution of function in the "two dinucleotide binding domains" flavoproteins.PLoS Comput Biol2007
16381950The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse.Nucleic Acids Res2006
16836757Tools for integrated sequence-structure analysis with UCSF Chimera.BMC Bioinformatics2006
16489747Leveraging enzyme structure-function relationships for functional inference and experimental design: the structure-function linkage database.Biochemistry2006
16344478Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: apoE structure as a potential therapeutic target.Proc Natl Acad Sci U S A2005
14660595Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions.J Biol Chem2004
15264254UCSF Chimera--a visualization system for exploratory research and analysis.J Comput Chem2004
15146493Superfamily active site templates.Proteins2004
12520002BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.Nucleic Acids Res2003
12520064The Structure Superposition Database.Nucleic Acids Res2003
12453150Constitutive activation and endocytosis of the complement factor 5a receptor: evidence for multiple activated conformations of a G protein-coupled receptor.Traffic2002
11062244An activation switch in the ligand binding pocket of the C5a receptor.J Biol Chem2001
11344266Mutant G protein alpha subunit activated by Gbeta gamma: a model for receptor activation?Proc Natl Acad Sci U S A2001
11698103Receptor activation: what does the rhodopsin structure tell us?Trends Pharmacol Sci2001
10950717Structure. Rhodopsin sees the light.Science2000
10336477C5a receptor activation. Genetic identification of critical residues in four transmembrane helices.J Biol Chem1999
10358054Similar structures and shared switch mechanisms of the beta2-adrenoceptor and the parathyroid hormone receptor. Zn(II) bridges between helices III and VI block activation.J Biol Chem1999
7964929Evaluating docked complexes with the HINT exponential function and empirical atomic hydrophobicities.J Comput Aided Mol Des1994
8340363Structure of a non-peptide inhibitor complexed with HIV-1 protease. Developing a cycle of structure-based drug design.J Biol Chem1993
8272425Orientational sampling and rigid-body minimization in molecular docking.Proteins1993
2258897A novel synthesis of xanthines: support for a new binding mode for xanthines with respect to adenosine at adenosine receptors.J Med Chem1990
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Collaborators

Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 16
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 15
University of California san francisco
Co-authored papers 11
University of California san francisco
Co-authored papers 11
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 8
Co-authored papers 7
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 5
University of California san francisco
Co-authored papers 5
University of California san francisco
Co-authored papers 4
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 4
University of California San Francisco
Co-authored papers 3
University of California San Francisco
Co-authored papers 3
Baylor College of Medicine
Co-authored papers 3
Wellcome Trust Sanger Institute
Co-authored papers 2
University of California san francisco
Co-authored papers 2
The Hebrew University of Jerusalem
Co-authored papers 2
and Clinical & Translational Science Institute, University of Pittsburgh
Co-authored papers 2
Institute of Data Science and Biotechnology, Gladstone Institutes
Co-authored papers 2
University of California san francisco
Co-authored papers 2
Odense University Hospital
Co-authored papers 2
Center for Visualization, Washington State University
Co-authored papers 2
Co-authored papers 2
Institute of Developmental Genetics, German Research Center for Environmental Health
Co-authored papers 1
Institute for Biophysical Chemistry, Goethe-University
Co-authored papers 1
University of California berkeley
Co-authored papers 1
Gladstone Institutes
Co-authored papers 1
Institute for Neurodegenerative Diseases, University of California san francisco
Co-authored papers 1
Center for Evolution and Cancer, University of California San Francisco San Francisco
Co-authored papers 1
University of California san francisco
Co-authored papers 1
University of California San Francisco
Co-authored papers 1