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Author Details

Thomas F Meyer
Max Planck Institute for Infection Biology
1979
388
90
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38090581γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids.Front Immunol2023
35292775Correction: TSPAN6 is a suppressor of Ras-driven cancer.Oncogene2022
35546639Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection.Nat Protoc2022
36585699DNA methylation in human gastric epithelial cells defines regional identity without restricting lineage plasticity.Clin Epigenetics2022
36514982IFNγ-dependent silencing of TFF1 during <i>Helicobacter pylori</i> infection.Open Biol2022
36271357Single object profiles regression analysis (SOPRA): a novel method for analyzing high-content cell-based screens.BMC Bioinformatics2022
36162648Human gastric fibroblasts ameliorate A20-dependent cell survival in co-cultured gastric epithelial cells infected by Helicobacter pylori.Biochim Biophys Acta Mol Cell Res2022
35184157TSPAN6 is a suppressor of Ras-driven cancer.Oncogene2022
35210413Modelling Chlamydia and HPV co-infection in patient-derived ectocervix organoids reveals distinct cellular reprogramming.Nat Commun2022
35332152BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation.Nat Commun2022
33462395Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia.Nat Cell Biol2021
33545196Discovery of Zika virus host dependency factors in trophoblasts using CRISPR/Cas9 screening.J Virol Methods2021
33585804Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.iScience2021
33579932Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells.Nat Commun2021
34752751Mechanistic dissection unmasks colibactin as a prevalent mutagenic driver of cancer.Cancer Cell2021
34328245TIFA has dual functions in Helicobacter pylori-induced classical and alternative NF-κB pathways.EMBO Rep2021
34155207SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.Nat Commun2021
33957136EGF and BMPs Govern Differentiation and Patterning in Human Gastric Glands.Gastroenterology2021
32195031The HIPPO pathway in gynecological malignancies.Am J Cancer Res2020
32009247Stable expansion of high-grade serous ovarian cancer organoids requires a low-Wnt environment.EMBO J2020
33037203The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress.Nat Commun2020
32843556<i>In Vivo</i> Genome and Methylome Adaptation of <i>cag</i>-Negative Helicobacter pylori during Experimental Human Infection.mBio2020
32866611Expression, purification and crystallization of CLK1 kinase - A potential target for antiviral therapy.Protein Expr Purif2020
32433976hGBP1 Coordinates Chlamydia Restriction and Inflammasome Activation through Sequential GTP Hydrolysis.Cell Rep2020
32483361Colibactin DNA-damage signature indicates mutational impact in colorectal cancer.Nat Med2020
29467166Polarised epithelial monolayers of the gastric mucosa reveal insights into mucosal homeostasis and defence against infection.Gut2019
31555351Elimination of HER3-expressing breast cancer cells using aptamer-siRNA chimeras.Exp Ther Med2019
31554819R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon.Nat Commun2019
31176694Regulation of influenza A virus mRNA splicing by CLK1.Antiviral Res2019
31235935R-spondin-3 induces secretory, antimicrobial Lgr5<sup>+</sup> cells in the stomach.Nat Cell Biol2019
30811500Correction: Contribution of the Cpx envelope stress system to metabolism and virulence regulation in Salmonella enterica serovar Typhimurium.PLoS One2019
31123891The Sweeping Role of Cholesterol Depletion in the Persistence of Helicobacter pylori Infections.Curr Top Microbiol Immunol2019
30704478Helicobacter pylori-controlled c-Abl localization promotes cell migration and limits apoptosis.Cell Commun Signal2019
30886143Chronic Chlamydia infection in human organoids increases stemness and promotes age-dependent CpG methylation.Nat Commun2019
30973879Model-based analysis of influenza A virus replication in genetically engineered cell lines elucidates the impact of host cell factors on key kinetic parameters of virus growth.PLoS Comput Biol2019
30883607RNAi-based small molecule repositioning reveals clinically approved urea-based kinase inhibitors as broadly active antivirals.PLoS Pathog2019
31111817Modulation of Host Cell Metabolism by Chlamydia trachomatis.Microbiol Spectr2019
31075211ADP heptose, a novel pathogen-associated molecular pattern identified in <i>Helicobacter pylori</i>.FASEB J2019
30716090Contribution of the Cpx envelope stress system to metabolism and virulence regulation in Salmonella enterica serovar Typhimurium.PLoS One2019
30699355Integrated Phosphoproteome and Transcriptome Analysis Reveals Chlamydia-Induced Epithelial-to-Mesenchymal Transition in Host Cells.Cell Rep2019
29317705Pneumolysin induced mitochondrial dysfunction leads to release of mitochondrial DNA.Sci Rep2018
30131271Thioloxidoreductase HP0231 of Helicobacter pylori impacts HopQ-dependent CagA translocation.Int J Med Microbiol2018
29937069Long-Term Culture of Distal Airway Epithelial Cells Allows Differentiation Towards Alveolar Epithelial Cells Suited for Influenza Virus Studies.EBioMedicine2018
30230643Genomic features of the Helicobacter pylori strain PMSS1 and its virulence attributes as deduced from its in vivo colonisation patterns.Mol Microbiol2018
30005951The Circadian Clock Regulates Metabolic Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal Cancer.EBioMedicine2018
30401777<i>Chlamydia trachomatis</i> Inhibits Homologous Recombination Repair of DNA Breaks by Interfering with PP2A Signaling.mBio2018
29706504Combined Human Genome-wide RNAi and Metabolite Analyses Identify IMPDH as a Host-Directed Target against Chlamydia Infection.Cell Host Microbe2018
29273450Helicobacter pylori Depletes Cholesterol in Gastric Glands to Prevent Interferon Gamma Signaling and Escape the Inflammatory Response.Gastroenterology2018
28765692<i>Helicobacter pylori</i> vacA genotype is a predominant determinant of immune response to <i>Helicobacter pylori</i> CagA.World J Gastroenterol2017
28289176Quantitative Proteomic Approach Identifies Vpr Binding Protein as Novel Host Factor Supporting Influenza A Virus Infections in Human Cells.Mol Cell Proteomics2017
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Collaborators

Alexander Karlas
Max Planck Institute for Infection Biology
Co-authored papers 20
Konstantin Okonechnikov
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 3
Laura Martin-Sancho
The Scripps Research Institute
Co-authored papers 2
Michael G Fehlings
University of Toronto Division of Neurosurgery and Spinal Program
Co-authored papers 2
Mark Achtman
Warwick Medical School, University of Warwick
Co-authored papers 2
Michael Vieth
Institute of Pathology, Friedrich-Alexander-University Erlangen-Nuremberg
Co-authored papers 2
Alexis Kaushansky
Seattle Children's Research Institute, University of Washington
Co-authored papers 2
Timothy C Wang
Division of Gastroenterology and Irvine Cancer Research Center, Columbia University
Co-authored papers 1
Juan Fueyo
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 1
Nikolai V Gorbunov
Armed Forces Radiobiology Research Institute
Co-authored papers 1
J. Wade Harper
Harvard Medical School
Co-authored papers 1
David M Sabatini
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 1
Wei-Chiang Shen
Suzhou Institute of Nano-Tech and Nano-Bionics (SINANO), Chinese Academy of Sciences
Co-authored papers 1
David Sulzer
New York State Psychiatric Institute, Research Foundation for Mental Hygiene
Co-authored papers 1
Randy A Albrecht
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Hans J Vogel
University of Calgary
Co-authored papers 1
Thomas J Begley
University at Albany
Co-authored papers 1
Silke Stertz
Institute of Medical Virology, University of Zurich
Co-authored papers 1
Jiri Mestecky
Co-authored papers 1
Carlos L??pez-Ot??n
Instituto Universitario de Oncologia, Universidad de Oviedo
Co-authored papers 1
Sara Cherry
University of Pennsylvania
Co-authored papers 1
Altuna Akalin
Berlin Institute for Medical Systems Biology
Co-authored papers 1
Svetlana Dokudovskaya
CNRS UMR9018, Institut Gustave Roussy, Universite Paris-Saclay
Co-authored papers 1
Jason E Gestwicki
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Karin Przyklenk
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Christopher R McMaster
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Release 1.2