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Author Details

Kevin Holden
Synthego Corporation
2002
20
14
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37563300Generation of precision preclinical cancer models using regulated in vivo base editing.Nat Biotechnol2024
36424489Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases.Nat Biotechnol2023
34343484Chemically modified guide RNAs enhance CRISPR-Cas13 knockdown in human cells.Cell Chem Biol2022
35839775Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2.Cell Rep2022
35589813Broad-spectrum CRISPR-mediated inhibition of SARS-CoV-2 variants and endemic coronaviruses in vitro.Nat Commun2022
35027731BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2.Nat Cell Biol2022
33333024Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses.Cell2021
33501440BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2.bioRxiv2021
33722289Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression.Genome Biol2021
34816261Viral E Protein Neutralizes BET Protein-Mediated Post-Entry Antagonism of SARS-CoV-2.bioRxiv2021
34320401Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication.Cell Rep2021
34012094In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels.Nat Biotechnol2021
32995787Functional genomic screens identify human host factors for SARS-CoV-2 and common cold coronaviruses.bioRxiv2020
33060197Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.Science2020
23651628Influence of arthritis-related protein (BBF01) on infectivity of Borrelia burgdorferi B31.BMC Microbiol2013
18316520Persistence of Borrelia burgdorferi following antibiotic treatment in mice.Antimicrob Agents Chemother2008
16584332Co-detection of Bartonella henselae, Borrelia burgdorferi, and Anaplasma phagocytophilum in Ixodes pacificus ticks from California, USA.Vector Borne Zoonotic Dis2006
15908372Coinfection with Anaplasma phagocytophilum alters Borrelia burgdorferi population distribution in C3H/HeN mice.Infect Immun2005
14680123Detection of Borrelia burgdorferi, Ehrlichia chaffeensis, and Anaplasma phagocytophilum in ticks (Acari: Ixodidae) from a coastal region of California.J Med Entomol2003
11875369Sequence variation and phylogenetic history of the mouse Ahr gene.Pharmacogenetics2002
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Collaborators

Jared Carlson-Stevermer
Synthego Corporation
Co-authored papers 8
Jennifer Oki
Synthego Corporation
Co-authored papers 8
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 5
Melanie Ott
Gladstone Institute of Virology
Co-authored papers 5
Jennifer M Hayashi
Gladstone Institutes
Co-authored papers 4
Marco Vignuzzi
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 3
Victor L Lam
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Zanlin Yu
University of California at San Francisco
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Mehdi Bouhaddou
J. David Gladstone Institutes
Co-authored papers 3
Amy Diallo
University of California san francisco
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Camille R Simoneau
Gladstone Institute of Virology
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Meghna Gupta
University of California san francisco
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Travis J Maures
University of Michigan Medical School ann arbor
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Erron W Titus
University of California san francisco
Co-authored papers 3
Alexander S Jureka
University of Alabama at Birmingham
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R??my Robinot
Institut Pasteur, Universite Paris Cite, CNRS UMR 9
Co-authored papers 2
Jesus A Silvas
Texas Biomedical Research Institutegrid.250889.e
Co-authored papers 2
Parinaz Fozouni
Gladstone Institute of Virology, Gladstone Institutes
Co-authored papers 2
Avi J Samelson
Institute for Neurodegenerative Diseases, University of California san francisco
Co-authored papers 2
James A Wells
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 2
Ruofan Wang
University of Maryland, College Park
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Yang Li
College of Chemistry, Jilin University
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Christopher F Basler
Icahn School of Medicine at Mount Sinai
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Irene Lui
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Bruce R Conklin
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