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Author Details

Ladan Fazli
University of British Columbia
2002
259
62
PMIDPaper TitleJournal TitlePublished Year
37676819Molecular features of prostate cancer after neoadjuvant therapy in the phase 3 CALGB 90203 trial.J Natl Cancer Inst2024
37847647Loss of feedback regulation between FAM3B and androgen receptor driving prostate cancer progression.J Natl Cancer Inst2024
36343786UGT2B28 accelerates prostate cancer progression through stabilization of the endocytic adaptor protein HIP1 regulating AR and EGFR pathways.Cancer Lett2023
37800655Semaphorin 3C promotes de novo steroidogenesis in prostate cancer cells.Endocr Relat Cancer2023
37425866RNF185 control of COL3A1 expression limits prostate cancer migration and metastatic potential.bioRxiv2023
37343766Artificial Intelligence-Based PTEN Loss Assessment as an Early Predictor of Prostate Cancer Metastasis After Surgery: A Multicenter Retrospective Study.Mod Pathol2023
36650183CRISPR screens reveal genetic determinants of PARP inhibitor sensitivity and resistance in prostate cancer.Nat Commun2023
36611121Chaperone-mediated autophagy promotes PCa survival during ARPI through selective proteome remodeling.Oncogene2023
36535377Dynamic phase separation of the androgen receptor and its coactivators key to regulate gene expression.Nucleic Acids Res2023
36727462SMAD3 promotes expression and activity of the androgen receptor in prostate cancer.Nucleic Acids Res2023
35965411DDX5 mRNA-targeting antisense oligonucleotide as a new promising therapeutic in combating castration-resistant prostate cancer.Mol Ther2023
33962883Receptor Activator of NF Kappa B (RANK) Expression Indicates Favorable Prognosis in Patients with Muscle-invasive Bladder Cancer.Eur Urol Focus2022
35647287Durable Surfaces from Film-Forming Silver Assemblies for Long-Term Zero Bacterial Adhesion without Toxicity.ACS Cent Sci2022
35780131The different prognostic significance of polysialic acid and CD56 expression in tumor cells and lymphocytes identified in breast cancer.NPJ Breast Cancer2022
36820095Robust Nanoparticle-Derived Lubricious Antibiofilm Coating for Difficult-to-Coat Medical Devices with Intricate Geometry.ACS Nanosci Au2022
35963852Reformation of the chondroitin sulfate glycocalyx enables progression of AR-independent prostate cancer.Nat Commun2022
36166584TP53 Alterations Are Associated With Poor Survival in Patients With Primary Mediastinal Nonseminoma Germ Cell Tumors.Oncologist2022
35014179THEM6-mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer.EMBO Mol Med2022
35094010Methylation-dependent and -independent roles of EZH2 synergize in CDCA8 activation in prostate cancer.Oncogene2022
34939643Regulation of AR mRNA translation in response to acute AR pathway inhibition.Nucleic Acids Res2022
35176252Development and validation of a quantitative reactive stroma biomarker (qRS) for prostate cancer prognosis.Hum Pathol2022
35145197Analysis of separate training and validation radical prostatectomy cohorts identifies 0.25â¿¿mm diameter as an optimal definition for "large" cribriform prostatic adenocarcinoma.Mod Pathol2022
34711954Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity.Oncogene2022
33420073Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer.Nat Commun2021
33795875A PRC2-independent function for EZH2 in regulating rRNA 2'-O methylation and IRES-dependent translation.Nat Cell Biol2021
33709547Androgen receptor (AR) antagonism triggers acute succinate-mediated adaptive responses to reactivate AR signaling.EMBO Mol Med2021
33750801A noncanonical AR addiction drives enzalutamide resistance in prostate cancer.Nat Commun2021
34706306CKB inhibits epithelial-mesenchymal transition and prostate cancer progression by sequestering and inhibiting AKT activation.Neoplasia2021
34489572An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer.Nat Cell Biol2021
34183356Stress-Mediated Reprogramming of Prostate Cancer One-Carbon Cycle Drives Disease Progression.Cancer Res2021
33985973SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer.Cancer Res2021
34199743Anti-Tumor Effects of Ginsenoside 20(S)-Protopanaxadiol and 1,25-Dihydroxyvitamin D3 Combination in Castration Resistant Prostate Cancer.Medicines (Basel)2021
34226953High fibroblast-activation-protein expression in castration-resistant prostate cancer supports the use of FAPI-molecular theranostics.Eur J Nucl Med Mol Imaging2021
34083096Evaluation of carbonic anhydrase IX as a potential therapeutic target in urothelial carcinoma.Urol Oncol2021
33250343A polymeric paste-drug formulation for local treatment of upper tract urothelial carcinoma.Urol Oncol2021
31567104Deep Learning-Based Gleason Grading of Prostate Cancer From Histopathology Images-Role of Multiscale Decision Aggregation and Data Augmentation.IEEE J Biomed Health Inform2020
31845908Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models.J Clin Invest2020
32046920Plasma Circulating Tumor DNA and Clonal Hematopoiesis in Metastatic Renal Cell Carcinoma.Clin Genitourin Cancer2020
31744831Identification of Hypermutation and Defective Mismatch Repair in ctDNA from Metastatic Prostate Cancer.Clin Cancer Res2020
31982308Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28.Mol Cell2020
31919137Transient Sox9 Expression Facilitates Resistance to Androgen-Targeted Therapy in Prostate Cancer.Clin Cancer Res2020
33126125Improving prostate cancer classification in H&E tissue micro arrays using Ki67 and P63 histopathology.Comput Biol Med2020
32634132LIN28B promotes the development of neuroendocrine prostate cancer.J Clin Invest2020
32847979Paternally Expressed Gene 10 (PEG10) Promotes Growth, Invasion, and Survival of Bladder Cancer.Mol Cancer Ther2020
32522824p300-Mediated Acetylation of Histone Demethylase JMJD1A Prevents Its Degradation by Ubiquitin Ligase STUB1 and Enhances Its Activity in Prostate Cancer.Cancer Res2020
32238799Histone demethylase JMJD1A promotes expression of DNA repair factors and radio-resistance of prostate cancer cells.Cell Death Dis2020
31462713BMI1 is directly regulated by androgen receptor to promote castration-resistance in prostate cancer.Oncogene2020
31630475The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer.Mol Oncol2020
30274982Proteogenomic Characterization of Patient-Derived Xenografts Highlights the Role of REST in Neuroendocrine Differentiation of Castration-Resistant Prostate Cancer.Clin Cancer Res2019
31760376Characterization of a Prostate- and Prostate Cancer-Specific Circular RNA Encoded by the Androgen Receptor Gene.Mol Ther Nucleic Acids2019
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Collaborators

Martin E Gleave
University of British Columbia
Co-authored papers 179
Antonio Hurtado-Coll
University of British Columbia
Co-authored papers 32
Amina Zoubeidi
University of British Columbia
Co-authored papers 30
Yuzhuo Wang
University of British Columbia
Co-authored papers 26
Colin C Collins
University of British Columbia
Co-authored papers 23
Alexander W Wyatt
University of British Columbia
Co-authored papers 21
Peter S Nelson
Fred Hutchinson Cancer Center
Co-authored papers 18
Lawrence D True
University of Washington School of Medicine
Co-authored papers 17
Dean A Troyer
Eastern Virginia Medical School
Co-authored papers 15
Daniel W Lin
Co-authored papers 15
Dong Lin
Fujian Medical University Cancer Hospital and Fujian Cancer Hospital
Co-authored papers 15
Ian M Thompson
CHRISTUS Santa Rosa Hospital-Medical Center
Co-authored papers 14
Hui Xue
Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences
Co-authored papers 11
Robert H Bell
University of British Columbia
Co-authored papers 11
Kim N Chi
University of British Columbia
Co-authored papers 10
Edward C Jones
University of British Columbia
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Himisha Beltran
Dana-Farber Cancer Institute
Co-authored papers 10
Anne Haegert
University of British Columbia
Co-authored papers 9
Estelle Li
University of British Columbia
Co-authored papers 9
Fan Mo
Institute of Stem Cell and Regeneration, Chinese Academy of Sciences
Co-authored papers 8
Matti Annala
University of British Columbia
Co-authored papers 8
Sonal Brahmbhatt
University of British Columbia
Co-authored papers 7
Raymond S Lance
Washington State University Elson S. Floyd College of Medicine
Co-authored papers 7
Ralph Buttyan
University of British Columbia
Co-authored papers 7
Jeremy A Squire
University of Sao Paulo
Co-authored papers 6
Shawn Anderson
University of British Columbia
Co-authored papers 6
Ian G Mills
Queen's University Belfast
Co-authored papers 5
Poul H Sorensen
British Columbia Cancer Research Centre
Co-authored papers 5
Stanislav V Volik
University of British Columbia
Co-authored papers 5
Mark A Rubin
University of Bern
Co-authored papers 5
Release 1.2