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Author Details

Leslie J Baier
1984
148
40
PMIDPaper TitleJournal TitlePublished Year
36862161The utility of a type 2 diabetes polygenic score in addition to clinical variables for prediction of type 2 diabetes incidence in birth, youth and adult cohorts in an Indigenous study population.2023
37783422Diagnostic criteria and etiopathogenesis of type 2 diabetes and its complications: Lessons from the Pima Indians.Presse Med2023
37148359The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes.Diabetologia2023
34655148A missense variant Arg611Cys in LIPE which encodes hormone sensitive lipase decreases lipolysis and increases risk of type 2 diabetes in American Indians.Diabetes Metab Res Rev2022
35688891Functional characterization of a novel p.Ser76Thr variant in IGFBP4 that associates with body mass index in American Indians.Eur J Hum Genet2022
35563754Generation of Isogenic hiPSCs with Targeted Edits at Multiple Intronic SNPs to Study the Effects of the Type 2 Diabetes Associated <i>KCNQ1</i> Locus in American Indians.Cells2022
35665752Association of protein function-altering variants with cardiometabolic traits: the strong heart study.Sci Rep2022
35043601Functional variants in cytochrome b5 type A (CYB5A) are enriched in Southwest American Indian individuals and associate with obesity.2022
33418499Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium.EBioMedicine2021
33616283Exome Sequencing of 21 Bardet-Biedl Syndrome (BBS) Genes to Identify Obesity Variants in 6,851 American Indians.Obesity (Silver Spring)2021
33875299Next generation sequencing for HLA loci in full heritage Pima Indians of Arizona, Part II: HLA-A, -B, and -C with selected non-classical loci at 4-field resolution from whole genome sequences.Hum Immunol2021
32640185Characterization of Exome Variants and Their Metabolic Impact in 6,716 American Indians from the Southwest US.Am J Hum Genet2020
31745258Identification and functional validation of genetic variants in potential miRNA target sites of established BMI genes.International Journal of Obesity2020
32424540Weight tracking in childhood and adolescence and type 2 diabetes risk.Diabetologia2020
32398872Assessing established BMI variants for a role in nighttime eating behavior in robustly phenotyped Southwestern American Indians.European Journal of Clinical Nutrition2020
32030914Low Serum Insulinlike Growth Factor II Levels Correlate with High BMI in American Indian Adults.2020
32886191Assessment of the potential role of natural selection in type 2 diabetes and related traits across human continental ancestry groups: comparison of phenotypic with genotypic divergence.Diabetologia2020
32818236Exome Sequencing Identifies A Nonsense Variant in DAO Associated With Reduced Energy Expenditure in American Indians.J Clin Endocrinol Metab2020
30887699Assessing the Role of 98 Established Loci for BMI in American Indians.2019
31706744Next generation sequencing and the classical HLA loci in full heritage Pima Indians of Arizona: Defining the core HLA variation for North American Paleo-Indians.Hum Immunol2019
31280340Association of CREBRF variants with obesity and diabetes in Pacific Islanders from Guam and Saipan.Diabetologia2019
31225870Atg7 Knockdown Reduces Chemerin Secretion in Murine Adipocytes.Journal of Clinical Endocrinology and Metabolism2019
31484069Peptide/Receptor Co-evolution Explains the Lipolytic Function of the Neuropeptide TLQP-21.Cell Reports2019
31111170Birthweight and early-onset type 2 diabetes in American Indians: differential effects in adolescents and young adults and additive effects of genotype, BMI and maternal diabetes.Diabetologia2019
29774533Analysis of type 2 diabetes and obesity genetic variants in Mexican Pima Indians: Marked allelic differentiation among Amerindians at HLA.Annals of Human Genetics2018
29483183HLA-B*07, HLA-DRB1*07, HLA-DRB1*12, and HLA-C*03:02 Strongly Associate With BMI: Data From 1.3 Million Healthy Chinese Adults.2018
29302047Functional and association analysis of an Amerindian-derived population-specific p.(Thr280Met) variant in RBPJL, a component of the PTF1 complex.European Journal of Human Genetics2018
29470850Identification and functional analysis of a novel G310D variant in the insulin-like growth factor 1 receptor (IGF1R) gene associated with type 2 diabetes in American Indians.Diabetes/Metabolism Research and Reviews2018
29423806Using Luciferase Reporter Assays to Identify Functional Variants at Disease-Associated Loci.Methods in Molecular Biology2018
28127622Differential methylation of genes in individuals exposed to maternal diabetes in utero.Diabetologia2017
28724990Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.Nat Commun2017
28490609A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants.Diabetes2017
28838971A Loss-of-Function Splice Acceptor Variant in <i>IGF2</i> Is Protective for Type 2 Diabetes.Diabetes2017
28476931A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in Associated With Reduced Energy Expenditure in American Indians.2017
29116125Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.Nat Commun2017
29155883Admixture mapping in the Hispanic Community Health Study/Study of Latinos reveals regions of genetic associations with blood pressure traits.PLoS One2017
29237685Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an <i>APOC3</i> Founder Mutation.Circ Cardiovasc Genet2017
27862917Assessing variation across 8 established East Asian loci for type 2 diabetes mellitus in American Indians: Suggestive evidence for new sex-specific diabetes signals in GLIS3 and ZFAND3.Diabetes/Metabolism Research and Reviews2017
28137830Admixture Mapping Identifies an Amerindian Ancestry Locus Associated with Albuminuria in Hispanics in the United States.J Am Soc Nephrol2017
26670163Assessment of established HDL-C loci for association with HDL-C levels and type 2 diabetes in Pima Indians.Diabetologia2016
26805783Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans.Am J Hum Genet2016
27076275The impact of genetic variants on BMI increase during childhood versus adulthood.International Journal of Obesity2016
26487785Analysis of SLC16A11 Variants in 12,811 American Indians: Genotype-Obesity Interaction for Type 2 Diabetes and an Association With RNASEK Expression.Diabetes2016
26246406ABCC8 R1420H Loss-of-Function Variant in a Southwest American Indian Community: Association With Increased Birth Weight and Doubled Risk of Type 2 Diabetes.Diabetes2015
25667308Role of Established Type 2 Diabetes-Susceptibility Genetic Variants in a High Prevalence American Indian Population.Diabetes2015
25662186A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians.Hum Mol Genet2015
27111117Complex Genetics of Type 2 Diabetes and Effect Size: What have We Learned from Isolated Populations?Review of Diabetic Studies2015
26308479The effect of differing patterns of childhood body mass index gain on adult physiology in American Indians.2015
26337673Assessing FOXO1A as a potential susceptibility locus for type 2 diabetes and obesity in American Indians.2015
25103139Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children.Human Genetics2014
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