Author details

Full Name

James C Fuscoe

Affiliation

ORCID

Career Start Year

1978

Papers

141

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36227756	Potential role of the apelin-APJ pathway in sex-related differential cardiotoxicity induced by doxorubicin in mice.	Journal of Applied Toxicology	2023
35199358	MicroRNA-34a-5p as a promising early circulating preclinical biomarker of doxorubicin-induced chronic cardiotoxicity.	Journal of Applied Toxicology	2022
34668590	Doxorubicin-induced delayed-onset subclinical cardiotoxicity in mice.	Journal of Applied Toxicology	2022
32749457	A comprehensive rat transcriptome built from large scale RNA-seq-based annotation.	Nucleic Acids Res	2020
32193355	Hepatic Transcript Profiles of Cytochrome P450 Genes Predict Sex Differences in Drug Metabolism.	Drug Metabolism and Disposition	2020
31989567	Simultaneous Quantification of t(14;18) and HPRT Exon 2/3 Deletions in Human Lymphocytes.	Methods in Molecular Biology	2020
30517846	Candidate early predictive plasma protein markers of doxorubicin-induced chronic cardiotoxicity in B6C3F mice.	Toxicology and Applied Pharmacology	2019
30316929	Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone.	Reproductive Toxicology	2018
28174625	Sex and age differences in the expression of liver microRNAs during the life span of F344 rats.	Biology of Sex Differences	2017
28189605	Transcriptomics analysis of early embryonic stem cell differentiation under osteoblast culture conditions: Applications for detection of developmental toxicity.	Reproductive Toxicology	2017
28125669	Stably Expressed Genes Involved in Basic Cellular Functions.	PLoS ONE	2017
27644598	Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F mice.	Toxicology and Applied Pharmacology	2016
26934058	Early metabolomics changes in heart and plasma during chronic doxorubicin treatment in B6C3F1 mice.	Journal of Applied Toxicology	2016
27103143	Status of hepatic DNA methylome predetermines and modulates the severity of non-alcoholic fatty liver injury in mice.	BMC Genomics	2016
26873546	Early transcriptional changes in cardiac mitochondria during chronic doxorubicin exposure and mitigation by dexrazoxane in mice.	Toxicology and Applied Pharmacology	2016
25862956	Effects of oral exposure to bisphenol A on gene expression and global genomic DNA methylation in the prostate, female mammary gland, and uterus of NCTR Sprague-Dawley rats.	Food and Chemical Toxicology	2015
25704921	Suppression of CYP2C9 by microRNA hsa-miR-128-3p in human liver cells and association with hepatocellular carcinoma.	Scientific Reports	2015
25539665	Persistence of furan-induced epigenetic aberrations in the livers of F344 rats.	Toxicological Sciences	2015
25653823	Age and sex differences in kidney microRNA expression during the life span of F344 rats.	Biology of Sex Differences	2015
25615628	Sexual dimorphism in the expression of mitochondria-related genes in rat heart at different ages.	PLoS ONE	2015
24875441	Toxicogenomics and cancer susceptibility: advances with next-generation sequencing.	Environmental Carcinogenesis and Ecotoxicology Reviews	2014
25448438	Early biomarkers of doxorubicin-induced heart injury in a mouse model.	Toxicology and Applied Pharmacology	2014
25977771	Comprehensive RNA-Seq transcriptomic profiling across 11 organs, 4 ages, and 2 sexes of Fischer 344 rats.	Sci Data	2014
24302446	Transcriptomic responses provide a new mechanistic basis for the chemopreventive effects of folic acid and tributyrin in rat liver carcinogenesis.	International Journal of Cancer	2014
24292225	Differential gene expression in human hepatocyte cell lines exposed to the antiretroviral agent zidovudine.	Archives of Toxicology	2014
24623238	Simultaneous quantification of t(14;18) and HPRT exon 2/3 deletions in human lymphocytes.	Methods in Molecular Biology	2014
24569495	Metzincins and related genes in experimental renal ageing: towards a unifying fibrosis classifier across species.	Nephrol Dial Transplant	2014
25015656	MicroRNA-155 deficient mice experience heightened kidney toxicity when dosed with cisplatin.	Toxicological Sciences	2014
24510058	A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages.	Nat Commun	2014
25150839	The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance.	Nat Biotechnol	2014
23142469	Development of doxorubicin-induced chronic cardiotoxicity in the B6C3F1 mouse model.	Toxicology and Applied Pharmacology	2013
24116033	Life cycle analysis of kidney gene expression in male F344 rats.	PLoS ONE	2013
23902594	Sex differences in kidney gene expression during the life cycle of F344 rats.	Biology of Sex Differences	2013
23393027	Studies on abacavir-induced hypersensitivity reaction: a successful example of translation of pharmacogenetics to personalized medicine.	Science China Life Sciences	2013
22480170	Expression analysis of hepatic mitochondria-related genes in mice exposed to acrylamide and glycidamide.	Journal of Toxicology and Environmental Health - Part A: Current Issues	2012
22655855	Characterization of whole genome amplified (WGA) DNA for use in genotyping assay development.	BMC Genomics	2012
22545210	Evaluation of Hepatic Mitochondria and Hematological Parameters in Zidovudine-Treated B6C3F(1) Mice.	AIDS Research and Treatment	2012
22421793	Modeling chemical interaction profiles: II. Molecular docking, spectral data-activity relationship, and structure-activity relationship models for potent and weak inhibitors of cytochrome P450 CYP3A4 isozyme.	Molecules	2012
22421792	Modeling chemical interaction profiles: I. Spectral data-activity relationship and structure-activity relationship models for inhibitors and non-inhibitors of cytochrome P450 CYP3A4 and CYP2D6 isozymes.	Molecules	2012
22573522	The liver toxicity biomarker study phase I: markers for the effects of tolcapone or entacapone.	Toxicol Pathol	2012
22872676	Interstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism.	FASEB Journal	2012
21845099	Identification and categorization of liver toxicity markers induced by a related pair of drugs.	International Journal of Molecular Sciences	2011
21389588	Microarray analysis of virulence gene profiles in Salmonella serovars from food/food animal environment.	J Infect Dev Ctries	2011
20938992	Coupling global methylation and gene expression profiles reveal key pathophysiological events in liver injury induced by a methyl-deficient diet.	Molecular Nutrition and Food Research	2011
21370286	MicroRNAs and their predicted target messenger RNAs are deregulated by exposure to a carcinogenic dose of comfrey in rat liver.	Environmental and Molecular Mutagenesis	2011
20013237	Application of microarray-based analysis of gene expression in the field of toxicogenomics.	Methods in Molecular Biology	2010
21170807	Metabolism, genotoxicity, and carcinogenicity of comfrey.	Journal of Toxicology and Environmental Health - Part B: Critical Reviews	2010
21118493	Age and sex dependent changes in liver gene expression during the life cycle of the rat.	BMC Genomics	2010
20676074	The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models.	Nat Biotechnol	2010
18824140	Effect of short-term exposure to zidovudine (AZT) on the expression of mitochondria-related genes in skeletal muscle of neonatal mice.	Mitochondrion	2009