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Author Details
Full Name
Jason Gertz
Affiliation
Huntsman Cancer Institute, University of Utah
ORCID
Career Start Year
2003
Papers
71
H Index
33
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36993565
<i>Cis</i>-regulatory control of transcriptional timing and noise in response to estrogen.
bioRxiv
2024
36930677
TXNIP loss expands Myc-dependent transcriptional programs by increasing Myc genomic binding.
PLoS Biol
2023
37275275
Estrogen receptor alpha mutations regulate gene expression and cell growth in breast cancer through microRNAs.
NAR Cancer
2023
37071732
Oct1 cooperates with the Smad family of transcription factors to promote mesodermal lineage specification.
Sci Signal
2023
37363949
Allele-Specific Gene Regulation, Phenotypes, and Therapeutic Vulnerabilities in Estrogen Receptor Alpha-Mutant Endometrial Cancer.
Mol Cancer Res
2023
36930833
FOXA1 Reprogramming Dictates Retinoid X Receptor Response in ESR1-Mutant Breast Cancer.
Mol Cancer Res
2023
34780648
MS4A3 promotes differentiation in chronic myeloid leukemia by enhancing common β-chain cytokine receptor endocytosis.
Blood
2022
35659930
Comprehensive evaluation and efficient classification of BRCA1 RING domain missense substitutions.
Am J Hum Genet
2022
36396974
Characterization of HCI-EC-23 a novel estrogen- and progesterone-responsive endometrial cancer cell line.
Sci Rep
2022
35221336
A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology.
Nat Cancer
2022
35078818
Hotspot ESR1 Mutations Are Multimodal and Contextual Modulators of Breast Cancer Metastasis.
Cancer Res
2022
32826305
Reciprocal regulation of pancreatic ductal adenocarcinoma growth and molecular subtype by HNF4α and SIX1/4.
Gut
2021
33850013
Brd4-bound enhancers drive cell-intrinsic sex differences in glioblastoma.
Proc Natl Acad Sci U S A
2021
34880227
A predominant enhancer co-amplified with the SOX2 oncogene is necessary and sufficient for its expression in squamous cancer.
Nat Commun
2021
34553212
Genetic demultiplexing of pooled single-cell RNA-sequencing samples in cancer facilitates effective experimental design.
Gigascience
2021
33184109
Estrogen Receptor Alpha Mutations in Breast Cancer Cells Cause Gene Expression Changes through Constant Activity and Secondary Effects.
Cancer Res
2021
33184106
Steroid Hormone Receptor and Infiltrating Immune Cell Status Reveals Therapeutic Vulnerabilities of <i>ESR1</i>-Mutant Breast Cancer.
Cancer Res
2021
33294922
A Positive Feedback Loop Between TGFβ and Androgen Receptor Supports Triple-negative Breast Cancer Anoikis Resistance.
Endocrinology
2021
32479598
Regulatory sharing between estrogen receptor α bound enhancers.
Nucleic Acids Res
2020
32046982
ETV4 Is Necessary for Estrogen Signaling and Growth in Endometrial Cancer Cells.
Cancer Res
2020
32004313
XPRESSyourself: Enhancing, standardizing, and automating ribosome profiling computational analyses yields improved insight into data.
PLoS Comput Biol
2020
32473656
MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate.
Cancer Cell
2020
32460686
Synergistic CRISPRa-Regulated Chondrogenic Extracellular Matrix Deposition Without Exogenous Growth Factors.
Tissue Eng Part A
2020
31140325
Lentiviral CRISPR Epigenome Editing of Inflammatory Receptors as a Gene Therapy Strategy for Disc Degeneration.
Hum Gene Ther
2019
31649055
FFPEcap-seq: a method for sequencing capped RNAs in formalin-fixed paraffin-embedded samples.
Genome Res
2019
31532389
NHR-14 loss of function couples intestinal iron uptake with innate immunity in <i>C. elegans</i> through PQM-1 signaling.
Elife
2019
31570515
Sufficiency analysis of estrogen responsive enhancers using synthetic activators.
Life Sci Alliance
2019
31362937
Estrogen-independent molecular actions of mutant estrogen receptor 1 in endometrial cancer.
Genome Res
2019
30712080
Estrogen Signaling in Endometrial Cancer: a Key Oncogenic Pathway with Several Open Questions.
Horm Cancer
2019
31164374
MYC-Driven Small-Cell Lung Cancer is Metabolically Distinct and Vulnerable to Arginine Depletion.
Clin Cancer Res
2019
29309061
GIGGLE: a search engine for large-scale integrated genome analysis.
Nat Methods
2018
29912188
Dissection of Enhancer Function Using Multiplex CRISPR-based Enhancer Interference in Cell Lines.
J Vis Exp
2018
30332632
The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment.
Immunity
2018
29539426
Clinical and Genomic Crosstalk between Glucocorticoid Receptor and Estrogen Receptor α In Endometrial Cancer.
Cell Rep
2018
28030809
Genomic regulation of invasion by STAT3 in triple negative breast cancer.
Oncotarget
2017
28089889
MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition.
Cancer Cell
2017
28964699
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor α-Bound Enhancers.
Cell Syst
2017
28676344
CRISPR Epigenome Editing of AKAP150 in DRG Neurons Abolishes Degenerative IVD-Induced Neuronal Activation.
Mol Ther
2017
28754123
Post-mortem molecular profiling of three psychiatric disorders.
Genome Med
2017
26787654
Multigene testing of moderate-risk genes: be mindful of the missense.
J Med Genet
2016
27565181
Cooperative Dynamics of AR and ER Activity in Breast Cancer.
Mol Cancer Res
2016
27282075
RNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long-term survival and reveals a role for ANGPTL4.
Mol Oncol
2016
27401066
Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation.
Genome Med
2016
26795348
Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus.
Cancer Res
2016
25890236
Improved survival among colon cancer patients with increased differentially expressed pathways.
BMC Med
2015
26486725
Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites.
Genome Res
2015
24299736
From single-cell to cell-pool transcriptomes: stochasticity in gene expression and RNA splicing.
Genome Res
2014
24929677
Recurrent read-through fusion transcripts in breast cancer.
Breast Cancer Res Treat
2014
23325432
Dynamic DNA methylation across diverse human cell lines and tissues.
Genome Res
2013
24279905
Mapping genome-wide transcription factor binding sites in frozen tissues.
Epigenetics Chromatin
2013
1 - 50 of 71
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Huntsman Cancer Institute, The University of Utah
Co-authored papers
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Katherine E Varley
Huntsman Cancer Institute
Co-authored papers
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Huntsman Cancer Institute
Co-authored papers
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Co-authored papers
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Co-authored papers
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Washington University School of Medicine
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4
Sara J Cooper
Co-authored papers
4
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Duke University
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Barbara J Wold
Merkin Institute for Translational Research, California Institute of Technology
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4
E Christopher Partridge
Co-authored papers
4
Aaron R Quinlan
University of Utah
Co-authored papers
3
Bryan E Welm
Co-authored papers
3
Gregory M Cooper
HudsonAlpha Institute for Biotechnology
Co-authored papers
3
Brian A Williams
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Anandaroop Mukhopadhyay
National University Hospital
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3
Georgi K Marinov
Co-authored papers
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William E Grizzle
University of Alabama at Birmingham
Co-authored papers
3
John A Stamatoyannopoulos
Altius Institute for Biomedical Sciences
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Ryan M Layer
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