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Author Details

Javed Khan
Center for Cancer Research, National Cancer Institute
1993
211
61
PMIDPaper TitleJournal TitlePublished Year
37688579Germline pathogenic variants in neuroblastoma patients are enriched in BARD1 and predict worse survival.J Natl Cancer Inst2024
37688579Germline pathogenic variants in neuroblastoma patients are enriched in BARD1 and predict worse survival.J Natl Cancer Inst2024
36322002The Combination of Trametinib and Ganitumab is Effective in RAS-Mutated PAX-Fusion Negative Rhabdomyosarcoma Models.Clin Cancer Res2023
36346688Predicting Molecular Subtype and Survival of Rhabdomyosarcoma Patients Using Deep Learning of H&E Images: A Report from the Children's Oncology Group.Clin Cancer Res2023
36322002The Combination of Trametinib and Ganitumab is Effective in RAS-Mutated PAX-Fusion Negative Rhabdomyosarcoma Models.Clin Cancer Res2023
37732905Piperacetazine Directly Binds to the PAX3::FOXO1 Fusion Protein and Inhibits Its Transcriptional Activity.Cancer Res Commun2023
37639593Myo-differentiation reporter screen reveals NF-Y as an activator of PAX3-FOXO1 in rhabdomyosarcoma.Proc Natl Acad Sci U S A2023
37706203Combined inhibition of topoisomerase I and poly(ADP-ribose) polymerase: A synergistic therapeutic strategy for glioblastoma with phosphatase and tensin homolog deficiency.Neurooncol Adv2023
37774704Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma.Cell Rep Med2023
36773602Genomic and transcriptomic analyses identify a prognostic gene signature and predict response to therapy in pleural and peritoneal mesothelioma.Cell Rep Med2023
36951526Germline genetic variants and pediatric rhabdomyosarcoma outcomes: a report from the Children's Oncology Group.J Natl Cancer Inst2023
36747619Germline pathogenic variants in 786 neuroblastoma patients.medRxiv2023
36607839A stem cell epigenome is associated with primary nonresponse to CD19 CAR T cells in pediatric acute lymphoblastic leukemia.Blood Adv2023
37706203Combined inhibition of topoisomerase I and poly(ADP-ribose) polymerase: A synergistic therapeutic strategy for glioblastoma with phosphatase and tensin homolog deficiency.Neurooncol Adv2023
37774704Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma.Cell Rep Med2023
37732905Piperacetazine Directly Binds to the PAX3::FOXO1 Fusion Protein and Inhibits Its Transcriptional Activity.Cancer Res Commun2023
37639593Myo-differentiation reporter screen reveals NF-Y as an activator of PAX3-FOXO1 in rhabdomyosarcoma.Proc Natl Acad Sci U S A2023
36951526Germline genetic variants and pediatric rhabdomyosarcoma outcomes: a report from the Children's Oncology Group.J Natl Cancer Inst2023
36747619Germline pathogenic variants in 786 neuroblastoma patients.medRxiv2023
36607839A stem cell epigenome is associated with primary nonresponse to CD19 CAR T cells in pediatric acute lymphoblastic leukemia.Blood Adv2023
36773602Genomic and transcriptomic analyses identify a prognostic gene signature and predict response to therapy in pleural and peritoneal mesothelioma.Cell Rep Med2023
36346688Predicting Molecular Subtype and Survival of Rhabdomyosarcoma Patients Using Deep Learning of H&E Images: A Report from the Children's Oncology Group.Clin Cancer Res2023
34187809Chromatin Mechanisms Driving Cancer.Cold Spring Harb Perspect Biol2022
35839732Molecular testing of rhabdomyosarcoma in clinical trials to improve risk stratification and outcome: A consensus view from European paediatric Soft tissue sarcoma Study Group, Children's Oncology Group and Cooperative Weichteilsarkom-Studiengruppe.Eur J Cancer2022
35877472FGFR4-Targeted Chimeric Antigen Receptors Combined with Anti-Myeloid Polypharmacy Effectively Treat Orthotopic Rhabdomyosarcoma.Mol Cancer Ther2022
35465663Dentithecamides A-H, Diacylated Zoanthoxanthin Derivatives with PAX3-FOXO1 Inhibitory Activity from the Hydroid <i>Dentitheca habereri</i>.J Nat Prod2022
34187809Chromatin Mechanisms Driving Cancer.Cold Spring Harb Perspect Biol2022
35839732Molecular testing of rhabdomyosarcoma in clinical trials to improve risk stratification and outcome: A consensus view from European paediatric Soft tissue sarcoma Study Group, Children's Oncology Group and Cooperative Weichteilsarkom-Studiengruppe.Eur J Cancer2022
35465663Dentithecamides A-H, Diacylated Zoanthoxanthin Derivatives with PAX3-FOXO1 Inhibitory Activity from the Hydroid <i>Dentitheca habereri</i>.J Nat Prod2022
35877472FGFR4-Targeted Chimeric Antigen Receptors Combined with Anti-Myeloid Polypharmacy Effectively Treat Orthotopic Rhabdomyosarcoma.Mol Cancer Ther2022
33468559Genome-Wide Analysis Unveils DNA Helicase RECQ1 as a Regulator of Estrogen Response Pathway in Breast Cancer Cells.Mol Cell Biol2021
35464627Exploring and Targeting the Tumor Immune Microenvironment of Neuroblastoma.J Cell Immunol2021
33741711<i>ZFTA</i> Translocations Constitute Ependymoma Chromatin Remodeling and Transcription Factors.Cancer Discov2021
34166228Serine hydroxymethyltransferase 2 expression promotes tumorigenesis in rhabdomyosarcoma with 12q13-q14 amplification.J Clin Invest2021
34166060Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium.J Clin Oncol2021
33848478Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress.Cancer Cell2021
33848174Neopetrothiazide: An Intriguing Pentacyclic Thiazide Alkaloid from the Sponge <i>Neopetrosia</i> sp.Org Lett2021
33627785FOXF1 is required for the oncogenic properties of PAX3-FOXO1 in rhabdomyosarcoma.Oncogene2021
34162872Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer.Nat Commun2021
33468559Genome-Wide Analysis Unveils DNA Helicase RECQ1 as a Regulator of Estrogen Response Pathway in Breast Cancer Cells.Mol Cell Biol2021
33520712Case Report: Single-Cell Transcriptomic Analysis of an Anaplastic Oligodendroglioma Post Immunotherapy.Front Oncol2021
33836455Ataxia telangiectasia mutated germline pathogenic variant in adrenocortical carcinoma.Cancer Genet2021
34258103Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma.Blood Cancer Discov2021
34195677CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice.Cell Rep Med2021
33504652Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair-targeted therapies.Sci Transl Med2021
34309174Consequences of hemophagocytic lymphohistiocytosis-like cytokine release syndrome toxicities and concurrent bacteremia.Pediatr Blood Cancer2021
33915882Prioritization of Novel Agents for Patients with Rhabdomyosarcoma: A Report from the Children's Oncology Group (COG) New Agents for Rhabdomyosarcoma Task Force.J Clin Med2021
33495553Beyond the storm - subacute toxicities and late effects in children receiving CAR T cells.Nat Rev Clin Oncol2021
33302115The prognostic significance of anaplasia in childhood rhabdomyosarcoma: A report from the Children's Oncology Group.Eur J Cancer2021
33299109Immunohistochemical detection of PAX-FOXO1 fusion proteins in alveolar rhabdomyosarcoma using breakpoint specific monoclonal antibodies.Mod Pathol2021
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Young K Song
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Qing-Rong Chen
Center for Biomedical Informatics and Information Technology
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Jack F Shern
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Paul S Meltzer
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John M Maris
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Stephen M Hewitt
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Sven Bilke
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Lee J Helman
Osteosarcoma Institute
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Chand Khanna
National Cancer Institute, National Institutes of Health
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Douglas S Hawkins
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Malcolm A Smith
National Cancer Institute
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Frederic G Barr
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Peter J Houghton
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Seth M Steinberg
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Braden T Greer
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Frank Westermann
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Craig C Whiteford
Kansas State University
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Markku Miettinen
National Cancer Institute
Co-authored papers 7
Charles Keller
Children's Cancer Therapy Development Institute
Co-authored papers 7
Yves Pommier
Center for Cancer Research, National Cancer Institute
Co-authored papers 7
Udayan Guha
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Daniela S Gerhard
National Cancer Institute
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Stephen J Chanock
National Cancer Institute, National Institutes of Health
Co-authored papers 7
Sharon J Diskin
Children's Hospital of Philadelphia
Co-authored papers 7
David M Langenau
MGH Pathology and Harvard Medical School
Co-authored papers 6
Yidong Chen
Zhujiang Hospital, Southern Medical University
Co-authored papers 6
Shaojian Gao
Co-authored papers 6
Beat W Sch??fer
Department of Oncology and Children's Research Center, University Children's Hospital
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Release 1.2