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Author Details

Luca A Lotta
2009
103
37
PMIDPaper TitleJournal TitlePublished Year
37523551Activin E-ACVR1C cross talk controls energy storage via suppression of adipose lipolysis in mice.2023
37954898Pharmacologic and Genetic Downregulation of Proprotein Convertase Subtilisin/Kexin Type 9 and Survival From Sepsis.Crit Care Explor2023
36807635Author Correction: Common and rare variant associations with clonal haematopoiesis phenotypes.Nature2023
35263815Thrombotic risk determined by rare and common SERPINA1 variants in a population-based cohort study.Journal of Thrombosis and Haemostasis2022
35654975A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation.Nat Genet2022
36357675Rare and common genetic determinants of metabolic individuality and their effects on human health.Nat Med2022
36090499Framework From a Multidisciplinary Approach for Transitioning Variants of Unknown Significance From Clinical Genetic Testing in Kidney Disease to a Definitive Classification.Kidney Int Rep2022
35999217Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes.Nat Commun2022
35939579Germline Mutations in <i>CIDEB</i> and Protection against Liver Disease.N Engl J Med2022
36062972Calcium, Its Regulatory Hormones, and Their Causal Role on Blood Pressure: A Two-Sample Mendelian Randomization Study.Journal of Clinical Endocrinology and Metabolism2022
36194491Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis.J Clin Invest2022
36381289Genetic variation of the blood coagulation regulator tissue factor pathway inhibitor and venous thromboembolism among middle-aged and older adults: A population-based cohort study.Research and Practice in Thrombosis and Haemostasis2022
36450978Common and rare variant associations with clonal haematopoiesis phenotypes.Nature2022
35915156Large-scale genome-wide association study of coronary artery disease in genetically diverse populations.Nat Med2022
34970867Thrombomodulin (THBD) gene variants and thrombotic risk in a population-based cohort study.Journal of Thrombosis and Haemostasis2022
35112923Classic Thrombophilias and Thrombotic Risk Among Middle-Aged and Older Adults: A Population-Based Cohort Study.Journal of the American Heart Association2022
34875679Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution.Journal of Clinical Endocrinology and Metabolism2022
34480422The genomics of heart failure: design and rationale of the HERMES consortium.ESC Heart Fail2021
33750426Genetic disruption of serine biosynthesis is a key driver of macular telangiectasia type 2 aetiology and progression.Genome Med2021
34120448Causal Effect of Adiposity Measures on Blood Pressure Traits in 2 Urban Swedish Cohorts: A Mendelian Randomization Study.J Am Heart Assoc2021
33798435Reply to Unreliability of genotyping arrays for detecting very rare variants in human genetic studies: Example from a recent study of MC4R.Cell2021
33727701Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.Nat Genet2021
34210852Sequencing of 640,000 exomes identifies <i>GPR75</i> variants associated with protection from obesity.Science2021
34184762Genome-wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals.Genet Epidemiol2021
33222547Clinical Evaluation of the Polygenetic Background of Blood Pressure in the Population-Based Setting.Hypertension2021
33414548A cross-platform approach identifies genetic regulators of human metabolism and health.Nat Genet2021
34855475Genetic and functional evidence links a missense variant in <i>B4GALT1</i> to lower LDL and fibrinogen.Science2021
34662886Exome sequencing and analysis of 454,787 UK Biobank participants.Nature2021
34945778Association of Thyroid Function with Blood Pressure and Cardiovascular Disease: A Mendelian Randomization.J Pers Med2021
32957805Genome-Wide Polygenic Score, Clinical Risk Factors, and Long-Term Trajectories of Coronary Artery Disease.Arterioscler Thromb Vasc Biol2020
31739742Functional Screening of Candidate Causal Genes for Insulin Resistance in Human Preadipocytes and Adipocytes.Circulation Research2020
32180562Genome-wide association study of adipocyte lipolysis in the GENetics of adipocyte lipolysis (GENiAL) cohort.Mol Metab2020
31707832Patients With High Genome-Wide Polygenic Risk Scores for Coronary Artery Disease May Receive Greater Clinical Benefit From Alirocumab Treatment in the ODYSSEY OUTCOMES Trial.Circulation2020
33096487Meta-analysis investigating the role of interleukin-6 mediated inflammation in type 2 diabetes.eBioMedicine2020
32916155Corrigendum to "Genome-wide association study of adipocyte lipolysis in the GENetics of adipocyte lipolysis (GENiAL) cohort" [Molecular Metabolism 34 (2020) 85-96].Mol Metab2020
33230300Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.Nat Genet2020
31151930MicroRNA-196a links human body fat distribution to adipose tissue extracellular matrix composition.EBioMedicine2019
30819905Complications of whole-exome sequencing for causal gene discovery in primary platelet secretion defects.Haematologica2019
31002796Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity.Cell2019
31155658The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies.Am J Epidemiol2019
30837465Assessing the causal association of glycine with risk of cardio-metabolic diseases.Nat Commun2019
29779155Prioritising Risk Factors for Type 2 Diabetes: Causal Inference through Genetic Approaches.Current Diabetes Reports2018
30029070Next-generation DNA sequencing to identify novel genetic risk factors for cerebral vein thrombosis.Thrombosis Research2018
30168256Targeted sequencing to identify novel genetic risk factors for deep vein thrombosis: a study of 734 genes.Journal of Thrombosis and Haemostasis2018
29916387Genomic insights into the causes of type 2 diabetes.Lancet, The2018
30575882Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.JAMA2018
30326043Association of Genetically Enhanced Lipoprotein Lipase-Mediated Lipolysis and Low-Density Lipoprotein Cholesterol-Lowering Alleles With Risk of Coronary Disease and Type 2 Diabetes.JAMA Cardiol2018
29899519Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.Nat Commun2018
30271922Genome-wide association study for risk taking propensity indicates shared pathways with body mass index.Communications Biology2018
29246479Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes.EBioMedicine2018
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