Author details

Full Name

Mahmoud Ghandi

Affiliation

ORCID

Career Start Year

2012

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37323575	Targeted <i>in silico</i> characterization of fusion transcripts in tumor and normal tissues via FusionInspector.	Cell Rep Methods	2023
34615655	Sex-Biased <i>ZRSR2</i> Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis.	Cancer Discov	2022
35383372	A tool for feature extraction from biological sequences.	Briefings in Bioinformatics	2022
34486523	Integrated evaluation of telomerase activation and telomere maintenance across cancer cell lines.	Elife	2021
33007263	Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs.	Cell	2020
32460014	Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes.	Cell Rep	2020
32855387	Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action.	Nat Commun	2020
31461650	Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors.	Cell Rep	2019
30971823	WRN helicase is a synthetic lethal target in microsatellite unstable cancers.	Nature	2019
31437130	DNA methyltransferase inhibition overcomes diphthamide pathway deficiencies underlying CD123-targeted treatment resistance.	J Clin Invest	2019
31068703	The landscape of cancer cell line metabolism.	Nat Med	2019
31068700	Next-generation characterization of the Cancer Cell Line Encyclopedia.	Nature	2019
29789628	Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models.	Nat Commun	2018
30089904	Genetic and transcriptional evolution alters cancer cell line drug response.	Nature	2018
28028240	Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers.	Proc Natl Acad Sci U S A	2017
28753430	Defining a Cancer Dependency Map.	Cell	2017
28837809	Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States.	Cell Syst	2017
29281820	Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes.	Cell Rep	2017
27604488	Systematic Functional Characterization of Resistance to PI3K Inhibition in Breast Cancer.	Cancer Discov	2016
27153639	gkmSVM: an R package for gapped-kmer SVM.	Bioinformatics	2016
27088724	Characterizing genomic alterations in cancer by complementary functional associations.	Nat Biotechnol	2016
27325104	Pediatric-type nodal follicular lymphoma: a biologically distinct lymphoma with frequent MAPK pathway mutations.	Blood	2016
26771021	The Molecular Signatures Database (MSigDB) hallmark gene set collection.	Cell Syst	2015
24562383	ARID1B is a specific vulnerability in ARID1A-mutant cancers.	Nat Med	2014
25490447	Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia.	Cancer Cell	2014
25320010	ERK mutations confer resistance to mitogen-activated protein kinase pathway inhibitors.	Cancer Res	2014
23861010	Robust k-mer frequency estimation using gapped k-mers.	Journal of Mathematical Biology	2014
25033408	Enhanced regulatory sequence prediction using gapped k-mer features.	PLoS Computational Biology	2014
23622249	Punctuated evolution of prostate cancer genomes.	Cell	2013
22140034	A mechanistic study on the effect of dexamethasone in moderating cell death in Chinese Hamster Ovary cell cultures.	Biotechnology Progress	2012
22912661	Group normalization for genomic data.	PLoS ONE	2012