Author details

Full Name

Jonathan P Lambert

Affiliation

ORCID

Career Start Year

2013

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37131819	MCU gain- and loss-of-function models define the duality of mitochondrial calcium uptake in heart failure.		2023
35779476	Altered composition of the mitochondrial Cauniporter in the failing human heart.	Cell Calcium	2022
36223763	Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure.	Cell Metab	2022
33092464	Interaction of the Joining Region in Junctophilin-2 With the L-Type Ca<sup>2+</sup> Channel Is Pivotal for Cardiac Dyad Assembly and Intracellular Ca<sup>2+</sup> Dynamics.	Circ Res	2021
32093523	MCUB and mitochondrial calcium uptake - modeling, function, and therapeutic potential.	Expert Opinion on Therapeutic Targets	2020
31533452	MCUB Regulates the Molecular Composition of the Mitochondrial Calcium Uniporter Channel to Limit Mitochondrial Calcium Overload During Stress.	Circulation	2019
31467276	Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer's disease.	Nature Communications	2019
30231993	Spatial Separation of Mitochondrial Calcium Uptake and Extrusion for Energy-Efficient Mitochondrial Calcium Signaling in the Heart.	Cell Reports	2018
27838154	Dysregulation of PINCH signaling in mesial temporal epilepsy.	Journal of Clinical Neuroscience	2017
28445457	The mitochondrial Na<sup>+</sup>/Ca<sup>2+</sup> exchanger is essential for Ca<sup>2+</sup> homeostasis and viability.	Nature	2017
28480026	Exercise training provides cardioprotection by activating and coupling endothelial nitric oxide synthase a Î²-adrenergic receptor-AMP-activated protein kinase signaling pathway.	Medical Gas Research	2017
27679746	Angiotensin type 2-receptor (AT2R) activation induces hypotension in apolipoprotein E-deficient mice by activating peroxisome proliferator-activated receptor-Î³.	American Journal of Cardiovascular Disease	2016
27108530	DJ-1 protects the heart against ischemia-reperfusion injury by regulating mitochondrial fission.	Journal of Molecular and Cellular Cardiology	2016
27056879	Sodium Sulfide Attenuates Ischemic-Induced Heart Failure by Enhancing Proteasomal Function in an Nrf2-Dependent Manner.	Circulation: Heart Failure	2016
27274047	IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction.	Proceedings of the National Academy of Sciences of the United States of America	2016
26119731	The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition.	Cell Rep	2015
25575644	Hydrogen sulfide attenuates high fat diet-induced cardiac dysfunction via the suppression of endoplasmic reticulum stress.	Nitric Oxide - Biology and Chemistry	2015
24813607	A proliferative burst during preadolescence establishes the final cardiomyocyte number.	Cell	2014
25525500	Hydrogen sulfide provides cardioprotection against myocardial/ischemia reperfusion injury in the diabetic state through the activation of the RISK pathway.	Medical Gas Research	2014
23349187	Thioredoxin 1 is essential for sodium sulfide-mediated cardioprotection in the setting of heart failure.	Arteriosclerosis, Thrombosis, and Vascular Biology	2013
23479260	Hydrogen sulfide preconditions the db/db diabetic mouse heart against ischemia-reperfusion injury by activating Nrf2 signaling in an Erk-dependent manner.	American Journal of Physiology - Heart and Circulatory Physiology	2013
23962643	Chronic exercise downregulates myocardial myoglobin and attenuates nitrite reductase capacity during ischemia-reperfusion.	Journal of Molecular and Cellular Cardiology	2013