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Author Details

John Graeme Hodgson
1996
40
30
PMIDPaper TitleJournal TitlePublished Year
36477975Targeting RARA overexpression with tamibarotene, a potent and selective RARα agonist, is a novel approach in AML.Blood Adv2023
35091442Phase II Study of Ponatinib in Advanced Gastrointestinal Stromal Tumors: Efficacy, Safety, and Impact of Liquid Biopsy and Other Biomarkers.Clinical Cancer Research2022
30042204Single-Molecule Sequencing Reveals Patterns of Preexisting Drug Resistance That Suggest Treatment Strategies in Philadelphia-Positive Leukemias.Clin Cancer Res2018
26603839Compound mutations in BCR-ABL1 are not major drivers of primary or secondary resistance to ponatinib in CP-CML patients.Blood2016
26773037The impact of multiple low-level BCR-ABL1 mutations on response to ponatinib.Blood2016
23172372Expression of miR-124 inhibits growth of medulloblastoma cells.Neuro Oncol2013
23836465Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancer.Journal of Pathology2013
22860045A comprehensive characterization of genome-wide copy number aberrations in colorectal cancer reveals novel oncogenes and patterns of alterations.PLoS One2012
22937035Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas.PLoS One2012
22393095Identification of a poor-prognosis BRAF-mutant-like population of patients with colon cancer.Journal of Clinical Oncology2012
22038996Targeted therapy for BRAFV600E malignant astrocytoma.Clin Cancer Res2011
21807965Progressive genomic instability in the FVB/Kras(LA2) mouse model of lung cancer.Mol Cancer Res2011
20093527Glioblastoma multiforme regional genetic and cellular expression patterns: influence on anatomic and physiologic MR imaging.Radiology2010
20129251Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1.Cancer Cell2010
20169192A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen.PLoS One2010
20068183Oncogenic BRAF mutation with CDKN2A inactivation is characteristic of a subset of pediatric malignant astrocytomas.Cancer Res2010
19843846Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality.Cancer Res2009
19139420Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts.Neuro Oncol2009
19731102microRNAs in gliomas: small regulators of a big problem.NeuroMolecular Medicine2009
18522749Mammary carcinoma behavior is programmed in the precancer stem cell.Breast Cancer Res2008
18577219miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells.BMC Med2008
16266989Copy number aberrations in mouse breast tumors reveal loci and genes important in tumorigenic receptor tyrosine kinase signaling.Cancer Res2005
15867356Shared epigenetic mechanisms in human and mouse gliomas inactivate expression of the growth suppressor SLC5A8.Cancer Res2005
16132578Syngeneic mouse mammary carcinoma cell lines: two closely related cell lines with divergent metastatic behavior.Clin Exp Metastasis2005
14744772The role of p53 in suppression of KSHV cyclin-induced lymphomagenesis.Cancer Res2004
15283211Array comparative genomic hybridization with cyanin cis-platinum-labeled DNAs.Biotechniques2004
15488760Absence of telomerase and shortened telomeres have minimal effects on skin and pancreatic carcinogenesis elicited by viral oncogenes.Cancer Cell2004
15466197Pancreatic insulinomas in multiple endocrine neoplasia, type I knockout mice can develop in the absence of chromosome instability or microsatellite instability.Cancer Res2004
15169571A murine leukemia virus with Cre-LoxP excisible coding sequences allowing superinfection, transgene delivery, and generation of host genomic deletions.Retrovirology2004
14871825TIMP-1 alters susceptibility to carcinogenesis.Cancer Research2004
15059892Oncogene expression and genetic background influence the frequency of DNA copy number abnormalities in mouse pancreatic islet cell carcinomas.Cancer Res2004
12755492Genome amplification of chromosome 20 in breast cancer.Breast Cancer Res Treat2003
14500357Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors.Cancer Res2003
12702876Induction of tumors in mice by genomic hypomethylation.Science2003
11133364Wild-type huntingtin reduces the cellular toxicity of mutant huntingtin in vivo.American Journal of Human Genetics2001
11694878Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas.Nat Genet2001
10402204A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.Neuron1999
10434304Evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease in cell culture and in transgenic mice expressing mutant huntingtin.Philos Trans R Soc Lond B Biol Sci1999
8702625Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme.Journal of Biological Chemistry1996
8968738Human huntingtin derived from YAC transgenes compensates for loss of murine huntingtin by rescue of the embryonic lethal phenotype.Human Molecular Genetics1996
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