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Author Details

Arkadiusz W Kulczyk
Institute for Quantitative Biomedicine, Rutgers University
2004
24
13
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36658135Cryo-EM reveals the molecular basis oflaminin polymerization and LN-lamininopathies.Nat Commun2023
37763837Novel Artificial Intelligence-Based Approaches for Ab Initio Structure Determination and Atomic Model Building for Cryo-Electron Microscopy.Micromachines (Basel)2023
36528064Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk reveals residues involved in the binding interaction.J Biol Chem2023
35104261A Robust Single-Particle Cryo-Electron Microscopy (cryo-EM) Processing Workflow with cryoSPARC, RELION, and Scipion.J Vis Exp2022
35461810You cannot oxidize what you cannot reach: Oxidative susceptibility of buried methionine residues.J Biol Chem2022
36474933Electron microscopy holdings of the Protein Data Bank: the impact of the resolution revolution, new validation tools, and implications for the future.Biophys Rev2022
36677177Exploring the Structural Variability of Dynamic Biological Complexes by Single-Particle Cryo-Electron Microscopy.Micromachines (Basel)2022
29905014A crystal structure of coil 1B of vimentin in the filamentous form provides a model of a high-order assembly of a vimentin filament.FEBS J2018
28223502Cryo-EM structure of the replisome reveals multiple interactions coordinating DNA synthesis.Proc Natl Acad Sci U S A2017
27241928The Replication System of Bacteriophage T7.Enzymes2016
27883039Structural and functional probing of PorZ, an essential bacterial surface component of the type-IX secretion system of human oral-microbiomic Porphyromonas gingivalis.Sci Rep2016
27889453Simultaneous Real-Time Imaging of Leading and Lagging Strand Synthesis Reveals the Coordination Dynamics of Single Replisomes.Mol Cell2016
24591606Single-molecule studies of polymerase dynamics and stoichiometry at the bacteriophage T7 replication machinery.Proc Natl Acad Sci U S A2014
22645372Molecular interactions in the priming complex of bacteriophage T7.Proc Natl Acad Sci U S A2012
22977246An interaction between DNA polymerase and helicase is essential for the high processivity of the bacteriophage T7 replisome.J Biol Chem2012
22761426Characterization of a nucleotide kinase encoded by bacteriophage T7.J Biol Chem2012
22887996Heterohexamer of 56- and 63-kDa Gene 4 Helicase-Primase of Bacteriophage T7 in DNA Replication.J Biol Chem2012
21245349Simultaneous single-molecule measurements of phage T7 replisome composition and function reveal the mechanism of polymerase exchange.Proc Natl Acad Sci U S A2011
21840995Coupling dTTP hydrolysis with DNA unwinding by the DNA helicase of bacteriophage T7.J Biol Chem2011
21697085Pyrovanadolysis, a pyrophosphorolysis-like reaction mediated by pyrovanadate, Mn2+, and DNA polymerase of bacteriophage T7.J Biol Chem2011
20332766Direct observation of enzymes replicating DNA using a single-molecule DNA stretching assay.J Vis Exp2010
20696935Conformational dynamics of bacteriophage T7 DNA polymerase and its processivity factor, Escherichia coli thioredoxin.Proc Natl Acad Sci U S A2010
18067538Inadequate inhibition of host RNA polymerase restricts T7 bacteriophage growth on hosts overexpressing udk.Mol Microbiol2008
15288782Solution structure and DNA binding of the zinc-finger domain from DNA ligase IIIalpha.J Mol Biol2004
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Collaborators

The Manton Center for Orphan Disease Research, Boston Children's Hospital
Co-authored papers 1
The State University of New Jersey
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Institute for Quantitative Biomedicine, the State University of New Jersey
Co-authored papers 1
Yuecheng District Centers for Disease Control and Prevention
Co-authored papers 1
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Co-authored papers 1
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Co-authored papers 1
Stanford University
Co-authored papers 1
Medical Research Council - Laboratory of Molecular Biology
Co-authored papers 1
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Co-authored papers 1
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Co-authored papers 1
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Co-authored papers 1
Institute for Quantitative Biomedicine, State University of New Jersey
Co-authored papers 1
The State University of New Jersey
Co-authored papers 1
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Co-authored papers 1
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Co-authored papers 1
Stanford University
Co-authored papers 1