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Author Details

Guillaume Pavlovic
CNRS, INSERM, Universite de Strasbourg, PHENOMIN-Institut Clinique de la Souris (ICS)
2002
36
20
PMIDPaper TitleJournal TitlePublished Year
36833328Increased On-Target Rate and Risk of Concatemerization after CRISPR-Enhanced Targeting in ES Cells.Genes (Basel)2023
37308929Development of HPV16 mouse and dog models for more accurate prediction of human vaccine efficacy.Lab Anim Res2023
36995673CRISMERE Chromosome Engineering in Mouse and Rat.Methods Mol Biol2023
34536110Importing genetically altered animals: ensuring quality.Mamm Genome2022
36551904Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models.Biomedicines2022
32721466Reliable and robust droplet digital PCR (ddPCR) and RT-ddPCR protocols for mouse studies.Methods2021
33838271Droplet digital PCR or quantitative PCR for in-depth genomic and functional validation of genetically altered rodents.Methods2021
34587162Dyrk1a gene dosage in glutamatergic neurons has key effects in cognitive deficits observed in mouse models of MRD7 and Down syndrome.PLoS Genet2021
34195895Introduction to mammalian genome special issue: the microbiome in human health and disease.Mamm Genome2021
32243835Variability in Genome Editing Outcomes: Challenges for Research Reproducibility and Clinical Safety.Mol Ther2020
32057313Modeling Down syndrome in animals from the early stage to the 4.0 models and next.Prog Brain Res2020
31086189TUBG1 missense variants underlying cortical malformations disrupt neuronal locomotion and microtubule dynamics but not neurogenesis.Nat Commun2019
31756054Optimizing PCR for Mouse Genotyping: Recommendations for Reliable, Rapid, Cost Effective, Robust and Adaptable to High-Throughput Genotyping Protocol for Any Type of Mutation.Curr Protoc Mouse Biol2019
29113787Nox4 genetic inhibition in experimental hypertension and metabolic syndrome.Arch Cardiovasc Dis2018
29870677Ketohexokinase knockout mice, a model for essential fructosuria, exhibit altered fructose metabolism and are protected from diet-induced metabolic defects.Am J Physiol Endocrinol Metab2018
29659809A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations.Hum Mol Genet2018
28065649Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome.Neuron2017
28266534Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE.Sci Rep2017
28677007Modeling human disease in rodents by CRISPR/Cas9 genome editing.Mamm Genome2017
28650483Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.Nat Genet2017
28851918Atp6ap2 ablation in adult mice impairs viability through multiple organ deficiencies.Sci Rep2017
27496052Aneuploidy screening of embryonic stem cell clones by metaphase karyotyping and droplet digital polymerase chain reaction.BMC Cell Biol2016
27621431E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis.Proc Natl Acad Sci U S A2016
27621313Physiological Expression of AMPKγ2RG Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice.J Biol Chem2016
26214591Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.Nat Genet2015
24574231Skin progenitor cells contribute to bleomycin-induced skin fibrosis.Arthritis Rheumatol2014
24336287Distinct fibroblast lineages determine dermal architecture in skin development and repair.Nature2013
22121025Highly-efficient, fluorescent, locus directed cre and FlpO deleter mice on a pure C57BL/6N genetic background.Genesis2012
22968824The mammalian gene function resource: the International Knockout Mouse Consortium.Mamm Genome2012
22961258Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project.Mamm Genome2012
22323709Absence of TI-VAMP/Vamp7 leads to increased anxiety in mice.J Neurosci2012
20453200PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain.J Lipid Res2010
19181800Conjugative transfer of the integrative conjugative elements ICESt1 and ICESt3 from Streptococcus thermophilus.J Bacteriol2009
15073287Evolution of genomic islands by deletion and tandem accretion by site-specific recombination: ICESt1-related elements from Streptococcus thermophilus.Microbiology (Reading)2004
12410819Conjugative transposons: the tip of the iceberg.Mol Microbiol2002
12383726The ICESt1 element of Streptococcus thermophilus belongs to a large family of integrative and conjugative elements that exchange modules and change their specificity of integration.Plasmid2002
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Collaborators

Yann Herault
Institut Clinique de la Souris (ICS), Universite de Strasbourg, CNRS, INSERM
Co-authored papers 26
Tania Sorg
Universite de Strasbourg, CNRS, INSERM, Institut de La Clinique de La Souris
Co-authored papers 13
Sara Wells
Mary Lyon Centre at Medical Research Council
Co-authored papers 5
Lauryl M J Nutter
The Hospital for Sick Children
Co-authored papers 4
Martin Hrab?? de Angelis
German Center for Diabetes Research (DZD e.V.)
Co-authored papers 4
Steve D M Brown
Mary Lyon Centre Harwell Science and Innovation Campus Oxfordshire UK.
Co-authored papers 4
Wolfgang Wurst
Institute of Developmental Genetics, German Research Center for Environmental Health
Co-authored papers 3
David J Adams
Wellcome Sanger Institute
Co-authored papers 3
Allan Bradley
The Wellcome Trust Sanger Institute
Co-authored papers 3
Hugh Morgan
MRC Harwell Institute
Co-authored papers 3
Valerie Gailus-Durner
Institute of Experimental Genetics, German Mouse Clinic
Co-authored papers 3
Gemma F Codner
Medical Research Council Harwell Institute
Co-authored papers 3
Natasha A Karp
Wellcome Sanger Institute
Co-authored papers 3
Colin McKerlie
The Hospital for Sick Children
Co-authored papers 3
Glauco P Tocchini-Valentini
Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR)
Co-authored papers 3
William C Skarnes
Wellcome Trust Sanger Institute
Co-authored papers 3
Ann-Marie Mallon
The Turing Institute
Co-authored papers 3
Jacqueline K White
Wellcome Trust Sanger Institute
Co-authored papers 3
Simon Greenaway
Harwell Institute
Co-authored papers 3
Kent C Lloyd
University of California davis
Co-authored papers 2
Luis Santos
The Turing Institute
Co-authored papers 2
Mark Moore
Co-authored papers 2
Michelle Stewart
Mary Lyon Centre at Medical Research Council
Co-authored papers 2
Henrik Westerberg
MRC Harwell Institute
Co-authored papers 2
Helmut Fuchs
Institute of Experimental Genetics, German Mouse Clinic
Co-authored papers 2
Janet Rossant
The Hospital for Sick Children
Co-authored papers 2
Ann M Flenniken
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 2
Je Kyung Seong
Seoul National University
Co-authored papers 2
Damian Smedley
William Harvey Research Institute, Queen Mary University of London
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Jeremy Mason
European Molecular Biology Laboratory - European Bioinformatics Institute
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Release 1.2