Author details

Full Name

Helen Skaletsky

Affiliation

ORCID

Career Start Year

1996

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36798326	A "Four Core Genotypes" rat model to distinguish mechanisms underlying sex-biased phenotypes and diseases.	bioRxiv	2023
37333288	The human Y and inactive X chromosomes similarly modulate autosomal gene expression.	bioRxiv	2023
36819663	The human inactive X chromosome modulates expression of the active X chromosome.	Cell Genom	2023
35676717	A gene deriving from the ancestral sex chromosomes was lost from the X and retained on the Y chromosome in eutherian mammals.	BMC Biology	2022
35700171	SHIMS 3.0: Highly efficient single-haplotype iterative mapping and sequencing using ultra-long nanopore reads.	PLoS ONE	2022
35554494	Genetic characterization of a missense mutation in the X-linked TAF7L gene identified in an oligozoospermic manâ¿ .	Biology of Reproduction	2022
34849781	GC-biased gene conversion in X-chromosome palindromes conserved in human, chimpanzee, and rhesus macaque.	G3: Genes, Genomes, Genetics	2021
34290043	Large palindromes on the primate X Chromosome are preserved by natural selection.	Genome Research	2021
33208454	Sequence analysis in <i>Bos taurus</i> reveals pervasiveness of X-Y arms races in mammalian lineages.	Genome Res	2020
31867688	Success rates in minimal stimulation cycle IVF with clomiphene citrate only.		2020
32461223	Quantitative analysis of Y-Chromosome gene expression across 36 human tissues.	Genome Res	2020
29565902	Cost-effective high-throughput single-haplotype iterative mapping and sequencing for complex genomic structures.		2018
30075113	Selection Has Countered High Mutability to Preserve the Ancestral Copy Number of Y Chromosome Amplicons in Diverse Human Lineages.	American Journal of Human Genetics	2018
28135246	Avian W and mammalian Y chromosomes convergently retained dosage-sensitive regulators.	Nat Genet	2017
28433372	Intrinsic fertility of human oocytes.	Fertility and Sterility	2017
27918550	Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining.	Nature Cell Biology	2017
27718356	A widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotes.	Elife	2016
26136358	TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse.	EMBO Molecular Medicine	2015
26017895	Sex chromosome-to-autosome transposition events counter Y-chromosome gene loss in mammals.		2015
24759411	Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators.	Nature	2014
25417157	Sequencing the mouse Y chromosome reveals convergent gene acquisition and amplification on both sex chromosomes.	Cell	2014
23643616	Intrachromosomal homologous recombination between inverted amplicons on opposing Y-chromosome arms.	Genomics	2013
24173037	No bull: upholding community standards in public sharing of biological datasets.	Proc Natl Acad Sci U S A	2013
23872635	Independent specialization of the human and mouse X chromosomes for the male germ line.	Nat Genet	2013
23103232	AZFc deletions and spermatogenic failure: a population-based survey of 20,000 Y chromosomes.	American Journal of Human Genetics	2012
22367542	Strict evolutionary conservation followed rapid gene loss on human and rhesus Y chromosomes.	Nature	2012
23055411	Sequencing of rhesus macaque Y chromosome clarifies origins and evolution of the DAZ (Deleted in AZoospermia) genes.	BioEssays	2012
20072128	Chimpanzee and human Y chromosomes are remarkably divergent in structure and gene content.	Nature	2010
20622855	Convergent evolution of chicken Z and human X chromosomes by expansion and gene acquisition.	Nature	2010
20004767	Remarkably little variation in proteins encoded by the Y chromosome's single-copy genes, implying effective purifying selection.	American Journal of Human Genetics	2009
19737515	Isodicentric Y chromosomes and sex disorders as byproducts of homologous recombination that maintains palindromes.	Cell	2009
17965095	MSY Breakpoint Mapper, a database of sequence-tagged sites useful in defining naturally occurring deletions in the human Y chromosome.	Nucleic Acids Research	2008
16872915	Ubl4b, an X-derived retrogene, is specifically expressed in post-meiotic germ cells in mammals.	Gene Expression Patterns	2007
16501575	High mutation rates have driven extensive structural polymorphism among human Y chromosomes.	Nature Genetics	2006
16874316	Has the chimpanzee Y chromosome been sequenced?	Nat Genet	2006
16136134	Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee.	Nature	2005
15178761	Selective pressures on the olfactory receptor repertoire since the human-chimpanzee divergence.	Proceedings of the National Academy of Sciences of the United States of America	2004
15258580	An X-to-autosome retrogene is required for spermatogenesis in mice.	Nature Genetics	2004
14528305	Polymorphism for a 1.6-Mb deletion of the human Y chromosome persists through balance between recurrent mutation and haploid selection.	Nature Genetics	2003
12620990	Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.	Development	2003
12815422	The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes.	Nature	2003
12815433	Abundant gene conversion between arms of palindromes in human and ape Y chromosomes.	Nature	2003
12297986	Recombination between palindromes P5 and P1 on the human Y chromosome causes massive deletions and spermatogenic failure.	American Journal of Human Genetics	2002
11237016	A physical map of the human Y chromosome.	Nature	2001
11687796	The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men.	Nat Genet	2001
10547847	Primer3 on the WWW for general users and for biologist programmers.	Methods in Molecular Biology	2000
10949301	Unexpectedly similar rates of nucleotide substitution found in male and female hominids.	Nature	2000
11001932	Deletion of azoospermia factor a (AZFa) region of human Y chromosome caused by recombination between HERV15 proviruses.	Human Molecular Genetics	2000
10936047	Four DAZ genes in two clusters found in the AZFc region of the human Y chromosome.	Genomics	2000
10581029	An azoospermic man with a de novo point mutation in the Y-chromosomal gene USP9Y.	Nat Genet	1999