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Author Details

David E Symer
The University of Texas MD Anderson Cancer Center
1984
44
25
PMIDPaper TitleJournal TitlePublished Year
36715691Intratumoral Heterogeneity and Clonal Evolution Induced by HPV Integration.Cancer Discov2023
37311413Single cell clonotypic and transcriptional evolution of multiple myeloma precursor disease.Cancer Cell2023
37004423Noninvasive genomic profiling of somatic mutations in oral cavity cancers.Oral Oncol2023
35621632Enrichment-Free Single-Cell Detection and Morphogenomic Profiling of Myeloma Patient Samples to Delineate Circulating Rare Plasma Cell Clones.Curr Oncol2022
31958486Human papillomavirus insertions identify the PIM family of serine/threonine kinases as targetable driver genes in head and neck squamous cell carcinoma.Cancer Lett2020
30563911Human papillomavirus and the landscape of secondary genetic alterations in oral cancers.Genome Res2019
30957677Identification of Rare Variants Predisposing to Thyroid Cancer.Thyroid2019
29449315Metaplastic breast cancer in a patient with neurofibromatosis type 1 and somatic loss of heterozygosity.Cold Spring Harb Mol Case Stud2018
29364907HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression.PLoS Genet2018
28049147Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus-Associated Merkel Cell Carcinoma.mBio2017
28378747HPV positive neuroendocrine cervical cancer cells are dependent on Myc but not E6/E7 viral oncogenes.Sci Rep2017
28491150Dynamic silencing of somatic L1 retrotransposon insertions reflects the developmental and cellular contexts of their genomic integration.Mob DNA2017
28790199In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.Circ Res2017
25419628The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection.Nat Immunol2015
26135620A germline mutation in SRRM2, a splicing factor gene, is implicated in papillary thyroid carcinoma predisposition.Sci Rep2015
25918370Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer.Proc Natl Acad Sci U S A2015
24201445Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability.Genome Res2014
24318829Collection and preparation of rodent embryonic samples for transcriptome study.Methods Mol Biol2014
24493738An antisense promoter in mouse L1 retrotransposon open reading frame-1 initiates expression of diverse fusion transcripts and limits retrotransposition.Nucleic Acids Res2014
23319453How do mammalian transposons induce genetic variation? A conceptual framework: the age, structure, allele frequency, and genome context of transposable elements may define their wide-ranging biological impacts.Bioessays2013
24130782Characterization of a new chronic lymphocytic leukemia cell line for mechanistic in vitro and in vivo studies relevant to disease.PLoS One2013
23690926Ultra-rare mutation in long-range enhancer predisposes to thyroid carcinoma with high penetrance.PLoS One2013
23539728SRGAP1 is a candidate gene for papillary thyroid carcinoma susceptibility.J Clin Endocrinol Metab2013
22367191Mouse endogenous retroviruses can trigger premature transcriptional termination at a distance.Genome Res2012
22722832The bonobo genome compared with the chimpanzee and human genomes.Nature2012
21474760Mutations in U4atac snRNA, a component of the minor spliceosome, in the developmental disorder MOPD I.Science2011
21549111The molecular and cellular basis of variable craniofacial phenotypes and their genetic rescue in Twisted gastrulation mutant mice.Dev Biol2011
19933259MouseIndelDB: a database integrating genomic indel polymorphisms that distinguish mouse strains.Nucleic Acids Res2010
20200603Roles of retrotransposons in benign and malignant hematologic disease.Cellscience2009
18381897Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition.Genome Res2008
18981014Oral human papillomavirus infection before and after treatment for human papillomavirus 16-positive and human papillomavirus 16-negative head and neck squamous cell carcinoma.Clin Cancer Res2008
18498648Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR.Retrovirology2008
12176320Human l1 retrotransposition is associated with genetic instability in vivo.Cell2002
11346774Genomic stability. Hip-hopping out of control.Nature2001
10793107Evidence for a causal association between human papillomavirus and a subset of head and neck cancers.J Natl Cancer Inst2000
9171897Low molecular weight antigen arrays delete high affinity memory B cells without affecting specific T-cell help.Mol Immunol1996
7499844Durable elimination of high affinity, T cell-dependent antibodies by low molecular weight antigen arrays in vivo.J Immunol1995
8346194A comparison of the immunogenicity of a pair of enantiomeric proteins.Proteins1993
8459221A requirement for membrane-associated phospholipase A2 in platelet cytotoxicity activated by receptors for immunoglobulin G and complement.J Exp Med1993
1402685Inhibition or activation of human T cell receptor transfectants is controlled by defined, soluble antigen arrays.J Exp Med1992
2056277Major histocompatibility complex independent T cell receptor-antigen interaction: functional analysis using fluorescein derivatives.J Exp Med1991
2742817Lysophosphatidylcholine metabolism to 1,2-diacylglycerol in lymphoblasts: involvement of a phosphatidylcholine-hydrolyzing phospholipase C.Biochemistry1989
3598464Platelet-mediated cytotoxicity. Role of antibody and C3, and localization of the cytotoxic system in membranes.J Exp Med1987
6376522Spectrin immunofluorescence distinguishes a population of naturally capped lymphocytes in situ.J Cell Biol1984
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Collaborators

The University of Texas MD Anderson Cancer Center
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The Ohio State University Comprehensive Cancer Center
Co-authored papers 7
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Co-authored papers 6
The Ohio State University Comprehensive Cancer Center, Comprehensive Cancer Center
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The Ohio State University
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Co-authored papers 2
Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw
Co-authored papers 2
AGH University of Science and Technology
Co-authored papers 2
Johns Hopkins University School of Medicine
Co-authored papers 2
Icahn School of Medicine at Mount Sinai Hospital.
Co-authored papers 2
Medical University of Warsaw
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Institute for Systems Genetics, NYU School of Medicine
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University of Michigan ann arbor
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Medical University of Warsaw
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Maria Sklodowska-Curie Institute - Oncology Centre
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Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology
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Maria Sklodowska-Curie Institute - Oncology Center
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Metagenomi Inc., Pre-clinical
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The University of Edinburgh
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