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Author Details

Renate K??nig
Paul-Ehrlich-Institut
1998
61
24
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37662193Gene editing of <i>SAMHD1</i> in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1 restriction and cellular dNTP levels.bioRxiv2023
37800914Gene editing of <i>SAMHD1</i> in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1 restriction, and cellular dNTP levels.mBio2023
34480199SAMHD1 in cancer: curse or cure?J Mol Med (Berl)2022
35809572Recognition of HIV-1 capsid by PQBP1 licenses an innate immune sensing of nascent HIV-1 DNA.Mol Cell2022
34298735Targeting Immune Modulators in Glioma While Avoiding Autoimmune Conditions.Cancers (Basel)2021
33810623Special Issue: "Innate Immune Sensing of Viruses and Viral Evasion".Viruses2021
33577922Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression.Neurobiol Dis2021
32401346SARS-CoV-2 immunogenicity at the crossroads.Allergy2020
31968566Sensor Sensibility-HIV-1 and the Innate Immune Response.Cells2020
31837633Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual.Stem Cell Res2020
32062129Generation of three induced pluripotent cell lines (iPSCs) from an Aicardi-Goutières syndrome (AGS) patient harboring a deletion in the genomic locus of the sterile alpha motif and HD domain containing protein 1 (SAMHD1).Stem Cell Res2020
33119711Correction: Y-box-binding protein 1 supports the early and late steps of HIV replication.PLoS One2020
32918599Designed Ankyrin Repeat Protein (DARPin) to target chimeric antigen receptor (CAR)-redirected T cells towards CD4<sup>+</sup> T cells to reduce the latent HIV<sup>+</sup> cell reservoir.Med Microbiol Immunol2020
30879196Intertwined: SAMHD1 cellular functions, restriction, and viral evasion strategies.Med Microbiol Immunol2019
31698189Induced pluripotent stem cells (iPSCs) derived from a renpenning syndrome patient with c.459_462delAGAG mutation in PQBP1 (PEIi001-A).Stem Cell Res2019
31779173Insights into Innate Sensing of Prototype Foamy Viruses in Myeloid Cells.Viruses2019
31824492Cathelicidin Contributes to the Restriction of <i>Leishmania</i> in Human Host Macrophages.Front Immunol2019
31455647ISG15 Deficiency Enhances HIV-1 Infection by Accumulating Misfolded p53.mBio2019
28685292Role of Innate Genes in HIV Replication.Curr Top Microbiol Immunol2018
29995936Y-box-binding protein 1 supports the early and late steps of HIV replication.PLoS One2018
29884836Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit.Nat Commun2018
30068654USP18 (UBP43) Abrogates p21-Mediated Inhibition of HIV-1.J Virol2018
28985145Virulence Profile: Renate König.Virulence2018
27909056Interferons Induce Expression of SAMHD1 in Monocytes through Down-regulation of miR-181a and miR-30a.J Biol Chem2017
28228523Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells.Proc Natl Acad Sci U S A2017
28248290Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation.Nat Microbiol2017
28233621Picking the Survivor! CRISPR Reveals HIV Dependency Factors.Trends Microbiol2017
28732199Catch Shiny Droplets in Suspension-Finding the Needle in a Haystack.Cell Chem Biol2017
27076174Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line.Sci Rep2016
26609934Interferon but not MxB inhibits foamy retroviruses.Virology2016
27229711Restrictive influence of SAMHD1 on Hepatitis B Virus life cycle.Sci Rep2016
27249646APOBEC4 Enhances the Replication of HIV-1.PLoS One2016
26733681Structure determination of helical filaments by solid-state NMR spectroscopy.Proc Natl Acad Sci U S A2016
27078069NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses.Cell Host Microbe2016
25609809High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus.J Virol2015
26355217BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency.Cell Host Microbe2015
26651948Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.Cell Host Microbe2015
26046437PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1.Cell2015
26112615Recent strategies and progress in identifying host factors involved in virus replication.Curr Opin Microbiol2015
24552952A neutralization assay for chikungunya virus infections in a multiplex format.J Virol Methods2014
24760882Tumor suppressor cylindromatosis (CYLD) controls HIV transcription in an NF-κB-dependent manner.J Virol2014
24586659Positive regulation of TRAF6-dependent innate immune responses by protein phosphatase PP1-γ.PLoS One2014
22972397SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.Nat Med2012
20654720Identifying HIV-1 host cell factors by genome-scale RNAi screening.Methods2011
21994773Systems-biology approaches to discover anti-viral effectors of the human innate immune response.Viruses2011
22174685SAMHD1-deficient CD14+ cells from individuals with Aicardi-Goutières syndrome are highly susceptible to HIV-1 infection.PLoS Pathog2011
21423673HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2.PLoS Pathog2011
20027183Human host factors required for influenza virus replication.Nature2010
19478882Host cell factors in HIV replication: meta-analysis of genome-wide studies.PLoS Pathog2009
18854154Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.Cell2008
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The Scripps Research Institute
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Co-authored papers 7
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Co-authored papers 6
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Nevan J Krogan (CM4AI)
University of California San Francisco
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Doris Steinemann
Hannover Medical School
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Sourav Bandyopadhyay
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Atsushi Inoue
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Lara Manganaro
National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi"
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Nirav Malani
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Release 1.2