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Author Details

Alexander Leitner
ETH Zurich
2001
112
42
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37861398Proteomic Profiling of Advanced Melanoma Patients to Predict Therapeutic Response to Anti-PD-1 Therapy.Clin Cancer Res2024
37861398Proteomic Profiling of Advanced Melanoma Patients to Predict Therapeutic Response to Anti-PD-1 Therapy.Clin Cancer Res2024
36928389A hybrid structure determination approach to investigate the druggability of the nucleocapsid protein of SARS-CoV-2.Nucleic Acids Res2023
37669508<i>RNxQuest</i>: An Extension to the <i>xQuest</i> Pipeline Enabling Analysis of Protein-RNA Cross-Linking/Mass Spectrometry Data.J Proteome Res2023
37833274Integrative solution structure of PTBP1-IRES complex reveals strong compaction and ordering with residual conformational flexibility.Nat Commun2023
37710014Conformational coupling of redox-driven Na<sup>+</sup>-translocation in Vibrio cholerae NADH:quinone oxidoreductase.Nat Struct Mol Biol2023
37699651Cross-linking mass spectrometric analysis of the endogenous TREX complex from <i>Saccharomyces cerevisiae</i>.RNA2023
37625406A hierarchical assembly pathway directs the unique subunit arrangement of TRiC/CCT.Mol Cell2023
37016670A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle.bioRxiv2023
37011209Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel.Proc Natl Acad Sci U S A2023
36866608Protein-RNA interactions: from mass spectrometry to drug discovery.Essays Biochem2023
36690744Towards a structurally resolved human protein interaction network.Nat Struct Mol Biol2023
37116473Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT.Cell2023
36928389A hybrid structure determination approach to investigate the druggability of the nucleocapsid protein of SARS-CoV-2.Nucleic Acids Res2023
36854761Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A.Nat Commun2023
37669508<i>RNxQuest</i>: An Extension to the <i>xQuest</i> Pipeline Enabling Analysis of Protein-RNA Cross-Linking/Mass Spectrometry Data.J Proteome Res2023
37710014Conformational coupling of redox-driven Na<sup>+</sup>-translocation in Vibrio cholerae NADH:quinone oxidoreductase.Nat Struct Mol Biol2023
37625406A hierarchical assembly pathway directs the unique subunit arrangement of TRiC/CCT.Mol Cell2023
37699651Cross-linking mass spectrometric analysis of the endogenous TREX complex from <i>Saccharomyces cerevisiae</i>.RNA2023
37833274Integrative solution structure of PTBP1-IRES complex reveals strong compaction and ordering with residual conformational flexibility.Nat Commun2023
37016670A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle.bioRxiv2023
37116473Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT.Cell2023
37011209Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel.Proc Natl Acad Sci U S A2023
36854761Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A.Nat Commun2023
36690744Towards a structurally resolved human protein interaction network.Nat Struct Mol Biol2023
36866608Protein-RNA interactions: from mass spectrometry to drug discovery.Essays Biochem2023
34929720Structural architecture of the human NALCN channelosome.Nature2022
35581222Nucleotide-amino acid Ï¿-stacking interactions initiate photo cross-linking in RNA-protein complexes.Nat Commun2022
35508485Enhancer RNAs stimulate Pol II pause release by harnessing multivalent interactions to NELF.Nat Commun2022
35366400Cross-linking and mass spectrometry as a tool for studying the structural biology of ribonucleoproteins.Structure2022
35864331Probing the secrets of probes.Nat Chem Biol2022
36493755Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT.Cell2022
35101980Sequence-specific RNA recognition by an RGG motif connects U1 and U2 snRNP for spliceosome assembly.Proc Natl Acad Sci U S A2022
34929720Structural architecture of the human NALCN channelosome.Nature2022
35508485Enhancer RNAs stimulate Pol II pause release by harnessing multivalent interactions to NELF.Nat Commun2022
35581222Nucleotide-amino acid Ï¿-stacking interactions initiate photo cross-linking in RNA-protein complexes.Nat Commun2022
35366400Cross-linking and mass spectrometry as a tool for studying the structural biology of ribonucleoproteins.Structure2022
36493755Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT.Cell2022
35864331Probing the secrets of probes.Nat Chem Biol2022
35101980Sequence-specific RNA recognition by an RGG motif connects U1 and U2 snRNP for spliceosome assembly.Proc Natl Acad Sci U S A2022
33399445Expanding the Cross-Link Coverage of a Carboxyl-Group Specific Chemical Cross-Linking Strategy for Structural Proteomics Applications.Anal Chem2021
36785722pH Dependence of Succinimide-Ester-Based Protein Cross-Linking for Structural Mass Spectrometry Applications.ACS Meas Sci Au2021
34158536Native mass spectrometry analyses of chaperonin complex TRiC/CCT reveal subunit N-terminal processing and re-association patterns.Sci Rep2021
33836586Structural and functional dissection of reovirus capsid folding and assembly by the prefoldin-TRiC/CCT chaperone network.Proc Natl Acad Sci U S A2021
34349113Puf6 primes 60S pre-ribosome nuclear export at low temperature.Nat Commun2021
33399445Expanding the Cross-Link Coverage of a Carboxyl-Group Specific Chemical Cross-Linking Strategy for Structural Proteomics Applications.Anal Chem2021
34714631Single Nucleotide Resolution RNA-Protein Cross-Linking Mass Spectrometry: A Simple Extension of the CLIR-MS Workflow.Anal Chem2021
34647674The human GID complex engages two independent modules for substrate recruitment.EMBO Rep2021
36785722pH Dependence of Succinimide-Ester-Based Protein Cross-Linking for Structural Mass Spectrometry Applications.ACS Meas Sci Au2021
33836586Structural and functional dissection of reovirus capsid folding and assembly by the prefoldin-TRiC/CCT chaperone network.Proc Natl Acad Sci U S A2021
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Collaborators

Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 46
Institute for Computational Biology
Co-authored papers 11
Stanford University
Co-authored papers 10
Medical Center, University of Freiburg
Co-authored papers 8
Institute of Molecular Biology and Biophysics, ETH Zurich
Co-authored papers 7
and Pharmacy, Freie Universitat Berlin
Co-authored papers 6
Stanford University
Co-authored papers 6
University of Konstanz Universitatsstrasse 10
Co-authored papers 6
Institute for Biotechnology, Technical University Berlin
Co-authored papers 5
IMP-Institute of Molecular Pathology
Co-authored papers 4
University of Zurich
Co-authored papers 4
ETH Zurich
Co-authored papers 4
Utrecht University
Co-authored papers 3
Institute of Systems, University of Liverpool
Co-authored papers 3
Utrecht University
Co-authored papers 3
University of Calgary, 0 Hospital Drive NW
Co-authored papers 3
Max Planck Institute of Biophysics
Co-authored papers 3
University of California Irvine
Co-authored papers 3
Utrecht Institute for Pharmaceutical Sciences, Utrecht University
Co-authored papers 3
Stanford University
Co-authored papers 3
University of California San Francisco
Co-authored papers 3
McGill University
Co-authored papers 2
Institute of Microbiology of the CAS
Co-authored papers 2
Center for Structural Mass Spectrometry, Martin Luther University Halle-Wittenberg
Co-authored papers 2
Technical University Darmstadt
Co-authored papers 2
EMBL-European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 2
Institute for Systems Biology
Co-authored papers 2
Johannes Gutenberg University Mainz
Co-authored papers 2
West China Hospital, Sichuan University
Co-authored papers 2
University Hospital Zurich
Co-authored papers 2