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Author Details

Theodore L Roth
Stanford University
2013
33
26
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36008610High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails.Nat Biotechnol2023
37938768Latent human herpesvirus 6 is reactivated in CAR T cells.Nature2023
36002574RASA2 ablation in T cells boosts antigen sensitivity and long-term function.Nature2022
35365639A functional map of HIV-host interactions in primary human T cells.Nat Commun2022
33351785TCF-1 regulates HIV-specific CD8+ T cell expansion capacity.JCI Insight2021
33883145XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment.Sci Adv2021
33682796Epithelial miR-141 regulates IL-13-induced airway mucus production.JCI Insight2021
33497260Genetic Disease and Therapy.Annu Rev Pathol2021
34970966Robust T cell activation requires an eIF3-driven burst in T cell receptor translation.Elife2021
32353859A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.Nature2020
31819258Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency.Nat Biotechnol2020
33060197Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.Science2020
32989329Functional CRISPR dissection of gene networks controlling human regulatory T cell identity.Nat Immunol2020
32415407Editing of Endogenous Genes in Cellular Immunotherapies.Curr Hematol Malig Rep2020
32499641CRISPR screen in regulatory T cells reveals modulators of Foxp3.Nature2020
30559373CRISPR-Cas9 genome engineering of primary CD4<sup>+</sup> T cells for the interrogation of HIV-host factor interactions.Nat Protoc2019
31757834Helios enhances the preferential differentiation of human fetal CD4<sup>+</sup> naïve T cells into regulatory T cells.Sci Immunol2019
31359007Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells.Nat Biotechnol2019
31182835Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function.Nat Biomed Eng2019
29614266Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins.J Immunol Methods2018
29889198Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms.J Vis Exp2018
29995861Reprogramming human T cell function and specificity with non-viral genome targeting.Nature2018
29899441Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation.Nature2018
30271925Light-activated cell identification and sorting (LACIS) for selection of edited clones on a nanofluidic device.Commun Biol2018
30449619Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function.Cell2018
28854172Discovery of stimulation-responsive immune enhancers with CRISPR activation.Nature2017
27487469Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node.Elife2016
25599342Inflammation and neuroprotection in traumatic brain injury.JAMA Neurol2015
26100903Single-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1.Proc Natl Acad Sci U S A2015
24471431Microglia development and function.Annu Rev Immunol2014
25226397A rapid and simple method for DNA engineering using cycled ligation assembly.PLoS One2014
24317693Transcranial amelioration of inflammation and cell death after brain injury.Nature2014
23737750Type I interferon programs innate myeloid dynamics and gene expression in the virally infected nervous system.PLoS Pathog2013
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Collaborators

Alexander Marson
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 22
Eric Shifrut
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 10
Joseph B Hiatt
Fred Hutchinson Cancer Center
Co-authored papers 8
Jonathan M Woo
University of California san francisco
Co-authored papers 7
Kathrin Schumann
Institute for Medical Microbiology, Technical University of Munich (TUM)
Co-authored papers 6
Victoria Tobin
California Institute of Technology
Co-authored papers 6
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 5
Chun Jimmie Ye
University of California san francisco
Co-authored papers 4
David N Nguyen
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 4
Michael J McGregor
J. David Gladstone Institutes
Co-authored papers 4
Dimitre R Simeonov
University of California San Francisco
Co-authored papers 4
Youjin V Lee
University of Chicago
Co-authored papers 4
Jacob E Corn
Co-authored papers 3
Andrew P May
Fluidigm Corporation
Co-authored papers 3
Ansuman T Satpathy
Stanford University
Co-authored papers 3
Mehdi Bouhaddou
J. David Gladstone Institutes
Co-authored papers 3
Julia Carnevale
University of California san francisco
Co-authored papers 3
Ujjwal Rathore
University of California san francisco
Co-authored papers 3
Ruby Yu
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 3
Alan Ashworth
UCSF Helen Diller Family Comprehensive Cancer Center
Co-authored papers 3
Kelsey M Haas
J. David Gladstone Institutes
Co-authored papers 3
Judd F Hultquist
Northwestern University Feinberg School of Medicine
Co-authored papers 3
Hannes Braberg
University of California San Francisco
Co-authored papers 2
David A Agard
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 2
Ying Shi
Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences
Co-authored papers 2
Jiewei Xu
Quantitative Biosciences Institute (QBI), University of California san francisco
Co-authored papers 2
Daniel J Saltzberg
University of California san francisco
Co-authored papers 2
Zun Zar Chi Naing
Quantitative Biosciences Institute (QBI), University of California San Francisco
Co-authored papers 2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 2
Danish Memon
European Bioinformatics Institute
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Release 1.2