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Author Details

Yael David
Tri-Institutional PhD Program in Chemical Biology
2010
40
18
PMIDPaper TitleJournal TitlePublished Year
36178424Harnessing Split-Inteins as a Tool for the Selective Modification of Surface Receptors in Live Cells.Chembiochem2023
37567151Incorporating chemical structures into scientific figures.Trends Biochem Sci2023
36993231Flexible and site-specific manipulation of histones in live animals.bioRxiv2023
37117416Nature-inspired protein ligation and its applications.Nat Rev Chem2023
37172287Chemoenzymatic Synthesis of Novel Cytotoxic Epoxyketones Using the Eponemycin Biosynthetic Enzyme EpnF.ACS Chem Biol2023
36804508Leveraging histone glycation for cancer diagnostics and therapeutics.Trends Cancer2023
34730874From Basic Biology Discovery to Translational Impact: The Boundless Roles of Chemical Biology.Chembiochem2022
35810158Chromatin sequesters pioneer transcription factor Sox2 from exerting force on DNA.Nat Commun2022
35484234Single-stranded nucleic acid binding and coacervation by linker histone H1.Nat Struct Mol Biol2022
36435807Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1.Nat Commun2022
34875212SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity.Mol Cell2022
35294181Chemical Labeling and Enrichment of Histone Glyoxal Adducts.ACS Chem Biol2022
34474548Diabetes mellitus and risk of plasma cell and lymphoproliferative disorders in 94,579 cases and 368,348 matched controls.Haematologica2022
33299182H1 histones control the epigenetic landscape by local chromatin compaction.Nature2021
34187895DOT1L complex regulates transcriptional initiation in human erythroleukemic cells.Proc Natl Acad Sci U S A2021
34157651A chemical field guide to histone nonenzymatic modifications.Curr Opin Chem Biol2021
33965314Non-enzymatic Covalent Modifications as a New Chapter in the Histone Code.Trends Biochem Sci2021
34355187Deglycase-activity oriented screening to identify DJ-1 inhibitors.RSC Med Chem2021
32356279Non-enzymatic covalent modifications: a new link between metabolism and epigenetics.Protein Cell2020
31875401Synthesis of an Alkynyl Methylglyoxal Probe to Investigate Nonenzymatic Histone Glycation.J Org Chem2020
32591537Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation.Nat Commun2020
32390412An Azidoribose Probe to Track Ketoamine Adducts in Histone Ribose Glycation.J Am Chem Soc2020
32144669In Vivo Histone Labeling Using Ultrafast trans-Splicing Inteins.Methods Mol Biol2020
30585724A Robust Method for the Purification and Characterization of Recombinant Human Histone H1 Variants.Biochemistry2019
31525994Targeting Hepatitis B Virus Covalently Closed Circular DNA and Hepatitis B Virus X Protein: Recent Advances and New Approaches.ACS Infect Dis2019
31606075Utilizing intein trans-splicing for in vivo generation of site-specifically modified proteins.Methods Enzymol2019
30839196(De)Toxifying the Epigenetic Code.Chem Res Toxicol2019
30894531Reversible histone glycation is associated with disease-related changes in chromatin architecture.Nat Commun2019
28069948Genomic targeting of epigenetic probes using a chemically tailored Cas9 system.Proc Natl Acad Sci U S A2017
28805803Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate.Nat Chem Biol2017
28635271Emerging Chemistry Strategies for Engineering Native Chromatin.J Am Chem Soc2017
25590432The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.PLoS One2015
26240340Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin.Proc Natl Acad Sci U S A2015
25901817Chemical tagging and customizing of cellular chromatin states using ultrafast trans-splicing inteins.Nat Chem2015
24429290Inherent asymmetry in the 26S proteasome is defined by the ubiquitin receptor RPN13.J Biol Chem2014
24997861Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries.Nat Methods2014
22859367From ubiquitin-proteasomal degradation to CDK1 inactivation: requirements for the first polar body extrusion in mouse oocytes.FASEB J2012
21722636SUMOylation of Blimp-1 promotes its proteasomal degradation.FEBS Lett2011
21965653E3 ligases determine ubiquitination site and conjugate type by enforcing specificity on E2 enzymes.J Biol Chem2011
20061386The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.J Biol Chem2010
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Collaborators

Tom W Muir
Princeton University
Co-authored papers 7
Shixin Liu
The Rockefeller University
Co-authored papers 3
Tuan Nguyen
The Rockefeller University
Co-authored papers 2
Robert G Roeder
the Rockefeller University
Co-authored papers 2
Rachel Leicher
The Rockefeller University
Co-authored papers 2
Paul G Young
Tri-Institutional MD-PhD Program
Co-authored papers 1
Gabriella N L Chua
The Rockefeller University
Co-authored papers 1
Johan Bostr??m
Karolinska Institutet
Co-authored papers 1
Xiaoyang Su
Cancer Institute of New Jersey
Co-authored papers 1
Adewola Osunsade
Tri-Institutional PhD Program in Chemical Biology
Co-authored papers 1
Arie Admon
Co-authored papers 1
Joshua D Rabinowitz
Lewis Sigler Institute for Integrative Genomics, Princeton University
Co-authored papers 1
Sarah C Faulkner
Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSKCC)
Co-authored papers 1
Benjamin A Garcia
University of Pennsylvania
Co-authored papers 1
Ariel Stanhill
Open University of Israel
Co-authored papers 1
Andrew P Latham
Massachusetts Institute of Technology, University of California, San Francisco, University of Notre Dame
Co-authored papers 1
Sophia Christodoulou-Rubalcava
Tri-Institutional PhD Program in Chemical Biology
Co-authored papers 1
David I Stuart
University of Oxford
Co-authored papers 1
Simone Sidoli
Co-authored papers 1
Mikael Altun
Karolinska Institutet
Co-authored papers 1
Bin Zhang
Massachusetts Institute of Technology
Co-authored papers 1
David H Perlman
Co-authored papers 1
Winfried Edelmann
Albert Einstein College of Medicine
Co-authored papers 1
John W Watters
The Rockefeller University
Co-authored papers 1
Ari Melnick
Co-authored papers 1
Jacob H Hanna
Co-authored papers 1
Emily C Beckwitt
Howard Hughes Medical Institute, The Rockefeller University
Co-authored papers 1
Cem Meydan
Co-authored papers 1
Release 1.2