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Author Details

??ngel Amesty
Instituto Universitario de Bio-Organica Antonio Gonzalez, Universidad de La Laguna
2006
30
10
PMIDPaper TitleJournal TitlePublished Year
36657273Phenolic and quinone methide nor-triterpenes as selective NLRP3 inflammasome inhibitors.Bioorg Chem2023
37169217Methyl esters of 23,24-Dinor-5α-cholan-22-oic acids as brassinosteroid Analogues. Synthesis, evaluation of plant growth promoting activity and Molecular docking.Steroids2023
36401841Labdane conjugates protect cardiomyocytes from doxorubicin-induced cardiotoxicity.Drug Dev Res2023
35890124Dehydroisohispanolone as a Promising NLRP3 Inhibitor Agent: Bioevaluation and Molecular Docking.Pharmaceuticals (Basel)2022
35631411Design, Semisynthesis, and Estrogenic Activity of Lignan Derivatives from Natural Dibenzylbutyrolactones.Pharmaceuticals (Basel)2022
36358593Discovery of Highly Functionalized 5-hydroxy-2<i>H</i>-pyrrol-2-ones That Exhibit Antiestrogenic Effects in Breast and Endometrial Cancer Cells and Potentiate the Antitumoral Effect of Tamoxifen.Cancers (Basel)2022
36355559Flavonoids from <i>Piper</i> Species as Promising Antiprotozoal Agents against <i>Giardia intestinalis</i>. Structure-Activity Relationship and Drug-Likeness Studies.Pharmaceuticals (Basel)2022
34069498<i>FLTX2</i>: A Novel Tamoxifen Derivative Endowed with Antiestrogenic, Fluorescent, and Photosensitizer Properties.Int J Mol Sci2021
34673425JKST6, a novel multikinase modulator of the BCR-ABL1/STAT5 signaling pathway that potentiates direct BCR-ABL1 inhibition and overcomes imatinib resistance in chronic myelogenous leukemia.Biomed Pharmacother2021
34681250Modular Synthesis and Antiproliferative Activity of New Dihydro-1<i>H</i>-pyrazolo[1,3-<i>b</i>]pyridine Embelin Derivatives.Pharmaceuticals (Basel)2021
32584575Dehydrohispanolone Derivatives Attenuate the Inflammatory Response through the Modulation of Inflammasome Activation.J Nat Prod2020
31876381Development of an in vitro screening assay for PIP5K1α lipid kinase and identification of potent inhibitors.FEBS J2020
31887475Design, synthesis and biological evaluation of new embelin derivatives as CK2 inhibitors.Bioorg Chem2020
33291428Withanolide-Type Steroids from <i>Withania aristata</i> as Potential Anti-Leukemic Agents.Molecules2020
32698422Efficient Multicomponent Synthesis of Diverse Antibacterial Embelin-Privileged Structure Conjugates.Molecules2020
29692264Metal Complexes of Natural Product Like-compounds with Antitumor Activity.Anticancer Agents Med Chem2019
31671684Synthesis and Antiplasmodial Activity of 1,2,3-Triazole-Naphthoquinone Conjugates.Molecules2019
31551765α-Hispanolol Induces Apoptosis and Suppresses Migration and Invasion of Glioblastoma Cells Likely <i>via</i> Downregulation of MMP-2/9 Expression and p38MAPK Attenuation.Front Pharmacol2019
31008605Expanding the Chemical Space of Withaferin A by Incorporating Silicon To Improve Its Clinical Potential on Human Ovarian Carcinoma Cells.J Med Chem2019
30687103A Novel Naphthoquinone-Coumarin Hybrid That Inhibits BCR-ABL1-STAT5 Oncogenic Pathway and Reduces Survival in Imatinib-Resistant Chronic Myelogenous Leukemia Cells.Front Pharmacol2019
29288942A new family of densely functionalized fused-benzoquinones as potent human protein kinase CK2 inhibitors.Eur J Med Chem2018
30518153Semisynthesis and Inhibitory Effects of Solidagenone Derivatives on TLR-Mediated Inflammatory Responses.Molecules2018
29346325Synthesis and Antimicrobial Activity of 4-Substituted 1,2,3-Triazole-Coumarin Derivatives.Molecules2018
28040393Synthesis and biological evaluation of naphthoquinone-coumarin conjugates as topoisomerase II inhibitors.Bioorg Med Chem Lett2017
282336785-Ethynylarylnaphthalimides as antitumor agents: Synthesis and biological evaluation.Bioorg Med Chem2017
29031065Synthesis and antibacterial activity of new symmetric polyoxygenated dibenzofurans.Eur J Med Chem2017
26076185Synthesis of 4,4'-Diaminotriphenylmethanes with Potential Selective Estrogen Receptor Modulator (SERM)-like Activity.ChemMedChem2015
24054489Synthesis and study of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides.Bioorg Med Chem2013
21504148Benzodihydrofurans from Cyperus teneriffae.J Nat Prod2011
16574358Ferutinin stimulates nitric oxide synthase activity in median eminence of the rat.J Ethnopharmacol2006
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Collaborators

Universidad Central de Venezuela
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University of California los angeles
Co-authored papers 1
Universidad de los Andes
Co-authored papers 1
School of Pharmacy, Universidad Central de Venezuela
Co-authored papers 1
School of Pharmacy, Universidad Central de Venezuela
Co-authored papers 1
School of Pharmacy, Universidad Central de Venezuela
Co-authored papers 1