Author details

Full Name

Yuqing E Chen

Affiliation

ORCID

Career Start Year

2000

Papers

275

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37502997	XBP1-mediated transcriptional regulation of SLC5A1 in human epithelial cells in disease conditions.		2023
36412196	Lp-PLA (Lipoprotein-Associated Phospholipase A) Deficiency Lowers Cholesterol Levels and Protects Against Atherosclerosis in Rabbits.	Arteriosclerosis, Thrombosis, and Vascular Biology	2023
37875990	ZSCAN4 interacts with PARP1 to promote DNA repair in mouse embryonic stem cells.		2023
37768825	Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis.		2023
37289544	Generating endogenous Myh11-driven Cre mice for sex-independent gene deletion in smooth muscle cells.		2023
36519469	Bicuspid Aortic Valve-Associated Regulatory Regions Reveal Regulation and Function During Human-Induced Pluripotent Stem Cell-Based Endothelial-Mesenchymal Transition-Brief Report.		2023
36711913	Fatty liver-mediated glycine restriction impairs glutathione synthesis and causes hypersensitization to acetaminophen.		2023
37079380	PRDM16 deficiency in vascular smooth muscle cells aggravates abdominal aortic aneurysm.		2023
37458631	Value of pelvic ultrasound combined with pituitary MRI in diagnosis of central precocious puberty in girls.		2023
36567267	Gasdermin D Deficiency in Vascular Smooth Muscle Cells Ameliorates Abdominal Aortic Aneurysm Through Reducing Putrescine Synthesis.		2023
37008888	Recent progress in polymeric gene vectors: Delivery mechanisms, molecular designs, and applications.		2023
37451479	Computational redesign of cytochrome P450 CYP102A1 for highly stereoselective omeprazole hydroxylation by UniDesign.		2023
37322547	Liver-specific in vivo base editing of Angptl3 via AAV delivery efficiently lowers blood lipid levels in mice.		2023
36995679	Generation of Rabbit Chimeras by Eight-Cell Stage Embryo Injection.		2023
37040763	DT-109 ameliorates nonalcoholic steatohepatitis in nonhuman primates.		2023
35306139	RNA sequencing reveals perivascular adipose tissue plasticity in response to angiotensin II.	Pharmacological Research	2022
36176648	KLF11 Is a Novel Endogenous Protectant against Renal Ischemia-Reperfusion Injury.		2022
36105190	Development of activated endothelial targeted high-density lipoprotein nanoparticles.	Frontiers in Pharmacology	2022
35447412	Induction of glutathione biosynthesis by glycine-based treatment mitigates atherosclerosis.	Redox Biology	2022
36015196	Effect of Lipid Composition on the Atheroprotective Properties of HDL-Mimicking Micelles.	Pharmaceutics	2022
35883629	Recent Advances in Improving Gene-Editing Specificity through CRISPR-Cas9 Nuclease Engineering.	Cells	2022
36139452	Myeloid Deficiency Inhibits Atherosclerosis.	Cells	2022
35365608	Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy.	Nature Communications	2022
36066968	BAF60c prevents abdominal aortic aneurysm formation through epigenetic control of vascular smooth muscle cell homeostasis.	Journal of Clinical Investigation	2022
35921817	CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder.		2022
36611948	Delivery of CRISPR/Cas9 Plasmid DNA by Hyperbranched Polymeric Nanoparticles Enables Efficient Gene Editing.		2022
33538785	KrÃ¼ppel-like factor 14 deletion in myeloid cells accelerates atherosclerotic lesion development.	Cardiovascular Research	2022
35278086	HDL quality features revealed by proteomeâ¿¿lipidome connectivity are associated with atherosclerotic disease.	Journal of Molecular Cell Biology	2022
35195259	A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study.	Eur Heart J	2022
35225256	Mouse Abdominal Aortic Aneurysm Model Induced by Perivascular Application of Elastase.	Journal of Visualized Experiments	2022
34661916	Liver-humanized mice: A translational strategy to study metabolic disorders.	Journal of Cellular Physiology	2022
34428834	KLF11 Protects against Venous Thrombosis via Suppressing Tissue Factor Expression.	Thrombosis and Haemostasis	2022
34474073	Exosomes from adipose-derived stem cells alleviate myocardial infarction via microRNA-31/FIH1/HIF-1Î± pathway.	Journal of Molecular and Cellular Cardiology	2022
34526909	Inhibition of a Novel CLK1-THRAP3-PPARÎ³ Axis Improves Insulin Sensitivity.	Frontiers in Physiology	2021
37724071	Gene editing therapy ready for cardiovascular diseases: opportunities, challenges, and perspectives.		2021
32448826	Endothelial Lipase Exerts its Anti-Atherogenic Effect through Increased Catabolism of Î²-VLDLs.	Journal of Atherosclerosis and Thrombosis	2021
33693786	An Asian-specific MPL genetic variant alters JAK-STAT signaling and influences platelet count in the population.	Hum Mol Genet	2021
33856594	Integration of Transformative Platforms for the Discovery of Causative Genes in Cardiovascular Diseases.	Cardiovascular Drugs and Therapy	2021
33852094	Translating Cardiovascular Genomics to Clinical Practice.	Cardiovascular Drugs and Therapy	2021
33584832	Gene Editing in Rabbits: Unique Opportunities for Translational Biomedical Research.	Frontiers in Genetics	2021
33535788	New Insight Into Metformin-Induced Cholesterol-Lowering Effect Crosstalk Between Glucose and Cholesterol Homeostasis via ChREBP (Carbohydrate-Responsive Element-Binding Protein)-Mediated PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Regulation.	Arteriosclerosis, Thrombosis, and Vascular Biology	2021
34051629	Biomimetic tubular scaffold with heparin conjugation for rapid degradation in in situ regeneration of a small diameter neoartery.	Biomaterials	2021
34051323	Improving the genome assembly of rabbits with long-read sequencing.	Genomics	2021
34265237	Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm.	Am J Hum Genet	2021
34095155	Single-Cell Transcriptomics Reveals Endothelial Plasticity During Diabetic Atherogenesis.	Frontiers in Cell and Developmental Biology	2021
33606990	Development of the Nude Rabbit Model.	Stem Cell Reports	2021
33603774	Genetically Modified Rabbits for Cardiovascular Research.	Frontiers in Genetics	2021
33651747	Genetic variants associated with cardiovascular diseases and related risk factors highlight novel potential therapeutic approaches.	Current Opinion in Lipidology	2021
34346740	hiPSC Modeling of Lineage-Specific Smooth Muscle Cell Defects Caused by <i>TGFBR1</i><sup><i>A230T</i></sup> Variant, and Its Therapeutic Implications for Loeys-Dietz Syndrome.	Circulation	2021
34320345	Dysregulated oxalate metabolism is a driver and therapeutic target in atherosclerosis.	Cell Reports	2021