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Author Details

Luke A Selth
Adelaide Medical School, University of Adelaide
2002
87
36
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36743527Targeting lipid metabolism in metastatic prostate cancer.Ther Adv Med Oncol2023
37673961Targeting hyaluronan-mediated motility receptor (HMMR) enhances response to androgen receptor signalling inhibitors in prostate cancer.Br J Cancer2023
37470668The Transcriptional and Epigenetic Landscape of Cancer Cell Lineage Plasticity.Cancer Discov2023
37174737Functional Characterisation of the Circular RNA, <i>circHTT(2-6)</i>, in Huntington's Disease.Cells2023
37295428Circular RNAs drive oncogenic chromosomal translocations within the MLL recombinome in leukemia.Cancer Cell2023
36859711Length of positive surgical margins after radical prostatectomy: Does size matter? - A systematic review and meta-analysis.Prostate Cancer Prostatic Dis2023
36923279Potent Stimulation of the Androgen Receptor Instigates a Viral Mimicry Response in Prostate Cancer.Cancer Res Commun2022
35764869Optical Cellular Micromotion: A New Paradigm to Measure Tumor Cells Invasion within Gels Mimicking the 3D Tumor Environments.Small Methods2022
33406413Post-transcriptional Gene Regulation by MicroRNA-194 Promotes Neuroendocrine Transdifferentiation in Prostate Cancer.Cell Rep2021
33547161ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer.Cancer Res2021
33834258TSC-insensitive Rheb mutations induce oncogenic transformation through a combination of constitutively active mTORC1 signalling and proteome remodelling.Cell Mol Life Sci2021
34737261Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer.Nat Commun2021
34489572An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer.Nat Cell Biol2021
34209750Regulation of mRNA Translation by Hormone Receptors in Breast and Prostate Cancer.Cancers (Basel)2021
34362796Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition.Cancer Res2021
34111999High-Throughput Imaging Assay for Drug Screening of 3D Prostate Cancer Organoids.SLAS Discov2021
33973331Primary Gleason grade and Gleason grade group at positive surgical margins: a systematic review and meta-analysis.BJU Int2021
33462444The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer.Nat Med2021
32209629Does Gleason score of positive surgical margin after radical prostatectomy affect biochemical recurrence and oncological outcomes? Protocol for systematic review.BMJ Open2020
31804971The epigenetic and transcriptional landscape of neuroendocrine prostate cancer.Endocr Relat Cancer2020
32878981SMOC1 is a glucose-responsive hepatokine and therapeutic target for glycemic control.Sci Transl Med2020
30508726Grainyhead-like-2 confers NK-sensitivity through interactions with epigenetic modifiers.Mol Immunol2019
30237440A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer.Oncogene2019
31556460Translational offsetting as a mode of estrogen receptor α-dependent regulation of gene expression.EMBO J2019
31200751Correction to: VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer.Genome Biol2019
30728288Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer.Sci Transl Med2019
31084623VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer.Genome Biol2019
30817318Interplay between the androgen receptor signaling axis and microRNAs in prostate cancer.Endocr Relat Cancer2019
30391670Long non-coding RNAs in prostate cancer: Biological and clinical implications.Mol Cell Endocrinol2019
29258679Role of Androgen Receptor Variants in Prostate Cancer: Report from the 2017 Mission Androgen Receptor Variants Meeting.Eur Urol2018
30049486Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy.Eur Urol2018
29871889miR-200/375 control epithelial plasticity-associated alternative splicing by repressing the RNA-binding protein Quaking.EMBO J2018
29391407Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion.Sci Rep2018
29497340Data Mining of Small RNA-Seq Suggests an Association Between Prostate Cancer and Altered Abundance of 5' Transfer RNA Halves in Seminal Fluid and Prostatic Tissues.Biomark Cancer2018
29703916A Plasma Biomarker Panel of Four MicroRNAs for the Diagnosis of Prostate Cancer.Sci Rep2018
29530945New Opportunities for Targeting the Androgen Receptor in Prostate Cancer.Cold Spring Harb Perspect Med2018
27270433A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer.Oncogene2017
28302679Disrupting Androgen Receptor Signaling Induces Snail-Mediated Epithelial-Mesenchymal Plasticity in Prostate Cancer.Cancer Res2017
28430625MiR-766 induces p53 accumulation and G2/M arrest by directly targeting MDM4.Oncotarget2017
28473532Novel Androgen Receptor Coregulator GRHL2 Exerts Both Oncogenic and Antimetastatic Functions in Prostate Cancer.Cancer Res2017
28092670Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality.Oncogene2017
28978635Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer.Cancer Res2017
28905400Somatostatin receptor subtype 1 as a potential diagnostic marker and therapeutic target in prostate cancer.Prostate2017
28011622MicroRNA-194 Promotes Prostate Cancer Metastasis by Inhibiting SOCS2.Cancer Res2017
27634452Cell-lineage specificity and role of AP-1 in the prostate fibroblast androgen receptor cistrome.Mol Cell Endocrinol2017
26940599Erratum to: IκBα mediates prostate cancer cell death induced by combinatorial targeting of the androgen receptor.BMC Cancer2016
27799360Androgen receptor signaling in castration-resistant prostate cancer: a lesson in persistence.Endocr Relat Cancer2016
27526951A Novel Class of Hsp90 C-Terminal Modulators Have Pre-Clinical Efficacy in Prostate Tumor Cells Without Induction of a Heat Shock Response.Prostate2016
27496708Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.Cancer Res2016
25597828Diagnostic performance of expression of PCA3, Hepsin and miR biomarkers inejaculate in combination with serum PSA for the detection of prostate cancer.Prostate2015
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Collaborators

Amina Zoubeidi
University of British Columbia
Co-authored papers 8
Jesper Q Svejstrup
Panum Institute, University of Copenhagen
Co-authored papers 7
Jason S Carroll
Co-authored papers 7
Gail P Risbridger
Biomedicine Discovery Institute, Monash University
Co-authored papers 6
Ganesh V Raj
University of Texas Southwestern Medical Center at Dallas
Co-authored papers 5
Renea A Taylor
Peter MacCallum Cancer Centre
Co-authored papers 5
Mitchell G Lawrence
Biomedicine Discovery Institute, Monash University
Co-authored papers 5
Stephen R Plymate
University of Washington
Co-authored papers 4
Martin E Gleave
University of British Columbia
Co-authored papers 4
Ian G Mills
Queen's University Belfast
Co-authored papers 3
Richard J Rebello
University of Melbourne
Co-authored papers 3
Alastair Davies
University of British Columbia
Co-authored papers 3
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Oncode Institute, The Netherlands Cancer Institute
Co-authored papers 3
Felix Y Feng
UCSF Medical Center-Mount Zion
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Himisha Beltran
Dana-Farber Cancer Institute
Co-authored papers 3
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South Australian Health and Medical Research Institute
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Monash University
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Andries M Bergman
The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital
Co-authored papers 2
Xiaochun Li
Co-authored papers 2
Ladan Fazli
University of British Columbia
Co-authored papers 2
Ashley E Ross
Northwestern University
Co-authored papers 2
Anne Y Warren
Cambridge University Hospitals National Health Service Foundation Trust
Co-authored papers 2
Florian Markowetz
CRUK Cambridge Institute, University of Cambridge
Co-authored papers 2
Kim N Chi
University of British Columbia
Co-authored papers 2
Charlie E Massie
University of Cambridge
Co-authored papers 2
David E Neal
University of Oxford, John Radcliffe Hospital
Co-authored papers 2
Carlos Caldas
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 2
Kaylene J Simpson
The University of Melbourne, Peter MacCallum Cancer Centre
Co-authored papers 2
Gerhard A Coetzee
Van Andel Institute
Co-authored papers 2
Release 1.2