Author details

Full Name

Simone Fulda

Affiliation

ORCID

Career Start Year

1995

Papers

382

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
35994517	Mathematical modeling of the molecular switch of TNFR1-mediated signaling pathways applying Petri net formalism and in silico knockout analysis.	PLoS Comput Biol	2022
34584066	The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma.	Cell Death Dis	2021
32401398	Quantitative single-molecule imaging of TNFR1 reveals zafirlukast as antagonist of TNFR1 clustering and TNFÎ±-induced NF-Ä¸B signaling.	Journal of Leukocyte Biology	2021
33971465	Smac mimetics and TRAIL cooperate to induce MLKL-dependent necroptosis in Burkitt's lymphoma cell lines.	Neoplasia	2021
33461384	Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death.		2021
33836590	Genetic deletion of Nox4 enhances cancerogen-induced formation of solid tumors.	Proceedings of the National Academy of Sciences of the United States of America	2021
33668084	Apoptotic Cells induce Proliferation of Peritoneal Macrophages.	International Journal of Molecular Sciences	2021
33369872	USP22 controls necroptosis by regulating receptor-interacting protein kinase 3 ubiquitination.	EMBO Reports	2021
33111629	ATF4 links ER stress with reticulophagy in glioblastoma cells.		2021
33321172	Organelle-specific mechanisms of drug-induced autophagy-dependent cell death.	Matrix Biology	2021
34373263	The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets.	Cancer Discov	2021
31352431	Thioredoxin inhibitor PX-12 induces mitochondria-mediated apoptosis in acute lymphoblastic leukemia cells.	Biological Chemistry	2020
31601689	Specific interactions of BCL-2 family proteins mediate sensitivity to BH3-mimetics in diffuse large B-cell lymphoma.	Haematologica	2020
32203216	A direct comparison of selective BH3-mimetics reveals BCL-X, BCL-2 and MCL-1 as promising therapeutic targets in neuroblastoma.	British Journal of Cancer	2020
32145345	Targeting BCL-2 proteins in pediatric cancer: Dual inhibition of BCL-X and MCL-1 leads to rapid induction of intrinsic apoptosis.	Cancer Letters	2020
31959760	STF-62247 and pimozide induce autophagy and autophagic cell death in mouse embryonic fibroblasts.	Scientific Reports	2020
32416440	Redox Modulation and Induction of Ferroptosis as a New Therapeutic Strategy in Hepatocellular Carcinoma.	Translational Oncology	2020
32012890	Combined Inhibition of Epigenetic Readers and Transcription Initiation Targets the EWS-ETS Transcriptional Program in Ewing Sarcoma.	Cancers (Basel)	2020
31831875	Next-generation hypomethylating agent SGI-110 primes acute myeloid leukemia cells to IAP antagonist by activating extrinsic and intrinsic apoptosis pathways.	Cell Death and Differentiation	2020
32170726	Proteasome inhibitors and Smac mimetics cooperate to induce cell death in diffuse large B-cell lymphoma by stabilizing NOXA and triggering mitochondrial apoptosis.	International Journal of Cancer	2020
31937565	Single-molecule imaging reveals the oligomeric state of functional TNFÎ±-induced plasma membrane TNFR1 clusters in cells.	Sci Signal	2020
32161312	Co-inhibition of BET proteins and PI3KÎ± triggers mitochondrial apoptosis in rhabdomyosarcoma cells.	Oncogene	2020
31755110	Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells.	International Journal of Cancer	2020
32445837	The novel dual BET/HDAC inhibitor TW09 mediates cell death by mitochondrial apoptosis in rhabdomyosarcoma cells.	Cancer Lett	2020
32978371	Correction: Smac mimetic suppresses tunicamycin-induced apoptosis via resolution of ER stress.	Cell Death and Disease	2020
32679165	The IRE1 and PERK arms of the unfolded protein response promote survival of rhabdomyosarcoma cells.	Cancer Letters	2020
33338048	ATM inhibition enhances Auranofin-induced oxidative stress and cell death in lung cell lines.	PLoS ONE	2020
31173656	Targeting ferroptosis in rhabdomyosarcoma cells.	International Journal of Cancer	2020
30770792	Smac mimetic suppresses tunicamycin-induced apoptosis via resolution of ER stress.	Cell Death and Disease	2019
31801941	Side-by-side comparison of BH3-mimetics identifies MCL-1 as a key therapeutic target in AML.	Cell Death and Disease	2019
31824851	A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas.	Front Oncol	2019
30312727	Identification of Smac mimetics as novel substrates for p-glycoprotein.	Cancer Letters	2019
30027602	Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications.		2019
29924730	Selective BH3-mimetics targeting BCL-2, BCL-XL or MCL-1 induce severe mitochondrial perturbations.	Biological Chemistry	2019
30391931	Differential involvement of TAK1, RIPK1 and NF-ÎºB signaling in Smac mimetic-induced cell death in breast cancer cells.	Biological Chemistry	2019
30521981	Interferons Transcriptionally Up-Regulate MLKL Expression in Cancer Cells.	Neoplasia	2019
30640794	Cotreatment with sorafenib and oleanolic acid induces reactive oxygen species-dependent and mitochondrial-mediated apoptotic cell death in hepatocellular carcinoma cells.	Anti-Cancer Drugs	2019
29777767	Biglycan is a new high-affinity ligand for CD14 in macrophages.	Matrix Biology	2019
30742091	Cell cycle arrest in mitosis promotes interferon-induced necroptosis.	Cell Death Differ	2019
31465840	Concomitant targeting of Hedgehog signaling and MCL-1 synergistically induces cell death in Hedgehog-driven cancer cells.	Cancer Letters	2019
30680482	NF-ÎºB contributes to Smac mimetic-conferred protection from tunicamycin-induced apoptosis.	Apoptosis : an international journal on programmed cell death	2019
30665942	Visualizing ubiquitination in mammalian cells.	EMBO Rep	2019
29230040	Congenital embryonal rhabdomyosarcoma caused by heterozygous concomitant PTCH1 and PTCH2 germline mutations.	Eur J Hum Genet	2018
28947136	BCL-x-selective BH3 mimetic sensitizes rhabdomyosarcoma cells to chemotherapeutics by activation of the mitochondrial pathway of apoptosis.	Cancer Letters	2018
30443311	Loss of the Chr16p11.2 ASD candidate gene leads to aberrant neuronal differentiation in the SH-SY5Y neuronal cell model.	Molecular Autism	2018
30250198	Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells.	Cell Death and Disease	2018
29858601	BCL-2 selective inhibitor ABT-199 primes rhabdomyosarcoma cells to histone deacetylase inhibitor-induced apoptosis.	Oncogene	2018
30319965	Different Response of <i>Ptch</i> Mutant and <i>Ptch</i> Wildtype Rhabdomyosarcoma Toward SMO and PI3K Inhibitors.	Front Oncol	2018
29939160	Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma.	J Clin Invest	2018
29938581	AT 101 induces early mitochondrial dysfunction and HMOX1 (heme oxygenase 1) to trigger mitophagic cell death in glioma cells.		2018