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Author Details

Michel A Cuendet
Precision Oncology Center, Lausanne University Hospital
2006
42
21
PMIDPaper TitleJournal TitlePublished Year
37328961Modeling tumor size dynamics based on real-world electronic health records and image data in advanced melanoma patients receiving immunotherapy.CPT Pharmacometrics Syst Pharmacol2023
37851498Testing a Model of Care for Patients on Immune Checkpoint Inhibitors Based on Electronic Patient-Reported Outcomes: Protocol for a Randomized Phase II Controlled Trial.JMIR Res Protoc2023
37025593Interactive process mining of cancer treatment sequences with melanoma real-world data.Front Oncol2023
37146261Semiautomated Pipeline to Quantify Tumor Evolution From Real-World Positron Emission Tomography/Computed Tomography Imaging.JCO Clin Cancer Inform2023
35298818Structural Prediction of Peptide-MHC Binding Modes.Methods Mol Biol2022
36612030Estimated Costs of the Ipilimumab-Nivolumab Therapy and Related Adverse Events in Metastatic Melanoma.Cancers (Basel)2022
36568192A differential process mining analysis of COVID-19 management for cancer patients.Front Oncol2022
35267470Safety and Efficacy of Ipilimumab plus Nivolumab and Sequential Selective Internal Radiation Therapy in Hepatic and Extrahepatic Metastatic Uveal Melanoma.Cancers (Basel)2022
31603792A Graphic Encoding Method for Quantitative Classification of Protein Structure and Representation of Conformational Changes.IEEE/ACM Trans Comput Biol Bioinform2021
33865201Late-onset and long-lasting immune-related adverse events from immune checkpoint-inhibitors: An overlooked aspect in immunotherapy.Eur J Cancer2021
33689297Probing the Conformational Dynamics of Affinity-Enhanced T Cell Receptor Variants upon Binding the Peptide-Bound Major Histocompatibility Complex by Hydrogen/Deuterium Exchange Mass Spectrometry.Biochemistry2021
35121945Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma.Nat Cancer2021
34764286Author Correction: Truly privacy-preserving federated analytics for precision medicine with multiparty homomorphic encryption.Nat Commun2021
34635645Truly privacy-preserving federated analytics for precision medicine with multiparty homomorphic encryption.Nat Commun2021
34656019Turning tumors from cold to inflamed to improve immunotherapy response.Cancer Treat Rev2021
34006992Unusual mode of dimerization of retinitis pigmentosa-associated F220C rhodopsin.Sci Rep2021
32932877What Role Can Process Mining Play in Recurrent Clinical Guidelines Issues? A Position Paper.Int J Environ Res Public Health2020
31836957The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients with brain metastases: a retrospective study.J Neurooncol2020
32570563SPHN/PHRT - MedCo in Action: Empowering the Swiss Molecular Tumor Board with Privacy-Preserving and Real-Time Patient Discovery.Stud Health Technol Inform2020
31704286CD8 Binding of MHC-Peptide Complexes in cis or trans Regulates CD8<sup>+</sup> T-cell Responses.J Mol Biol2019
29153319Thermodynamic Coupling Function Analysis of Allosteric Mechanisms in the Human Dopamine Transporter.Biophys J2018
30134695Endpoint-restricted adiabatic free energy dynamics approach for the exploration of biomolecular conformational equilibria.J Chem Phys2018
29756037Substrate-modulated unwinding of transmembrane helices in the NSS transporter LeuT.Sci Adv2018
28671821The T-Cell Receptor Can Bind to the Peptide-Bound Major Histocompatibility Complex and Uncomplexed β<sub>2</sub>-Microglobulin through Distinct Binding Sites.Biochemistry2017
29117524Cholesterol Promotes Protein Binding by Affecting Membrane Electrostatics and Solvation Properties.Biophys J2017
26892914Allosteric Mechanisms of Molecular Machines at the Membrane: Transport by Sodium-Coupled Symporters.Chem Rev2016
27766843The Allostery Landscape: Quantifying Thermodynamic Couplings in Biomolecular Systems.J Chem Theory Comput2016
25652997Transport domain unlocking sets the uptake rate of an aspartate transporter.Nature2015
24620905How accurately do current force fields predict experimental peptide conformations? An adiabatic free energy dynamics study.J Phys Chem B2014
26588271Free Energy Reconstruction from Metadynamics or Adiabatic Free Energy Dynamics Simulations.J Chem Theory Comput2014
24062738Structure-Based, Rational Design ofâ¿¿T Cell Receptors.Front Immunol2013
22803523Heating and flooding: a unified approach for rapid generation of free energy surfaces.J Chem Phys2012
26592999Alchemical Free Energy Differences in Flexible Molecules from Thermodynamic Integration or Free Energy Perturbation Combined with Driven Adiabatic Dynamics.J Chem Theory Comput2012
21541964SwissParam: a fast force field generation tool for small organic molecules.J Comput Chem2011
21989928How T cell receptors interact with peptide-MHCs: a multiple steered molecular dynamics study.Proteins2011
20101644Use of the FACTS solvation model for protein-ligand docking calculations. Application to EADock.J Mol Recognit2010
26617301Implementation of the CHARMM Force Field in GROMACS: Analysis of Protein Stability Effects from Correction Maps, Virtual Interaction Sites, and Water Models.J Chem Theory Comput2010
18621828Protein-protein interaction investigated by steered molecular dynamics: the TCR-pMHC complex.Biophys J2008
17676788Optical spectra of Cu(II)-azurin by hybrid TDDFT-molecular dynamics simulations.J Phys Chem B2007
18020625On the calculation of velocity-dependent properties in molecular dynamics simulations using the leapfrog integration algorithm.J Chem Phys2007
16605888Statistical mechanical derivation of Jarzynski's identity for thermostated non-Hamiltonian dynamics.Phys Rev Lett2006
17042581The Jarzynski identity derived from general Hamiltonian or non-Hamiltonian dynamics reproducing NVT or NPT ensembles.J Chem Phys2006
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Collaborators

Harel Weinstein
Institute for Computational Biomedicine
Co-authored papers 5
Sylvain Pradervand
Co-authored papers 4
Melita Irving
Guy's and St Thomas' NHS Foundation Trust, Evelina Children's Hospital
Co-authored papers 4
Jean-Pierre Hubaux
EPFL.
Co-authored papers 3
Jacques Fellay
Ecole Polytechnique Federale de Lausanne
Co-authored papers 3
Jean Louis Raisaro
University Hospital Lausanne, University of Lausanne
Co-authored papers 3
Joao Sa Sousa
EPFL.
Co-authored papers 3
Juan R Troncoso-Pastoriza
EPFL.
Co-authored papers 3
Bonnie Berger
Massachusetts Institute of Technology
Co-authored papers 2
Hyunghoon Cho
Broad Institute of MIT and Harvard, Massachusetts Institute of Technology, Stanford University, Yale University
Co-authored papers 2
Richard A Scolyer
Co-authored papers 1
David Froelicher
Co-authored papers 1
David Froelicher
Co-authored papers 1
Georgina V Long
Co-authored papers 1
Russ B Altman
Stanford University
Co-authored papers 1
Release 1.2