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Author Details

Nancy Su
2000
19
16
PMIDPaper TitleJournal TitlePublished Year
32988967AZD4320, A Dual Inhibitor of Bcl-2 and Bcl-x<sub>L</sub>, Induces Tumor Regression in Hematologic Cancer Models without Dose-limiting Thrombocytopenia.Clin Cancer Res2020
31699827AZD4573 Is a Highly Selective CDK9 Inhibitor That Suppresses MCL-1 and Induces Apoptosis in Hematologic Cancer Cells.Clin Cancer Res2020
31606346Discovery and optimization of covalent Bcl-xL antagonists.Bioorg Med Chem Lett2019
29266803Structure-Based Design of Selective Noncovalent CDK12 Inhibitors.ChemMedChem2018
30297535Pharmacological Inhibition of PARP6 Triggers Multipolar Spindle Formation and Elicits Therapeutic Effects in Breast Cancer.Cancer Res2018
29152055Correction to "Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors".ACS Med Chem Lett2017
27578247Modulating the strength of hydrogen bond acceptors to achieve low Caco2 efflux for oral bioavailability of PARP inhibitors blocking centrosome clustering.Bioorg Med Chem Lett2016
28197319Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors.ACS Med Chem Lett2016
27595327Inhibition of Mcl-1 through covalent modification of a noncatalytic lysine side chain.Nat Chem Biol2016
25815142Pyrimidinone nicotinamide mimetics as selective tankyrase and wnt pathway inhibitors suitable for in vivo pharmacology.ACS Med Chem Lett2015
26546219Discovery of AZ0108, an orally bioavailable phthalazinone PARP inhibitor that blocks centrosome clustering.Bioorg Med Chem Lett2015
25458601Discovery of potent KIFC1 inhibitors using a method of integrated high-throughput synthesis and screening.J Med Chem2014
23895133Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1.ACS Chem Biol2013
24900464Potent and Selective Inhibitors of CK2 Kinase Identified through Structure-Guided Hybridization.ACS Med Chem Lett2012
18775810Effects of the JAK2 inhibitor, AZ960, on Pim/BAD/BCL-xL survival signaling in the human JAK2 V617F cell line SET-2.J Biol Chem2008
17964784Spermatinamine, the first natural product inhibitor of isoprenylcysteine carboxyl methyltransferase, a new cancer target.Bioorg Med Chem Lett2007
14759518Functional silencing of hepatic microsomal glucose-6-phosphatase gene expression in vivo by adenovirus-mediated delivery of short hairpin RNA.FEBS Lett2004
11532142Genome-wide analysis of the general stress response in Bacillus subtilis.Mol Microbiol2001
11007778The enoyl-[acyl-carrier-protein] reductases FabI and FabL from Bacillus subtilis.J Biol Chem2000
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Collaborators

Michael Zinda
Repare Therapeutics Inc.
Co-authored papers 4
Stephanos Ioannidis
H3 Biomedicine Inc.
Co-authored papers 4
Justin Cidado
Oncology R&D
Co-authored papers 3
Stephen Fawell
Oncology R&D
Co-authored papers 3
Deborah Lawson
Oncology R&D
Co-authored papers 2
Jamal C Saeh
Oncology R&D
Co-authored papers 2
Jeffrey G Varnes
Oncology R&D
Co-authored papers 2
Steven W Criscione
Oncology R&D
Co-authored papers 2
Edward J Hennessy
Oncology R&D
Co-authored papers 2
Xiahui Zhu
Co-authored papers 2
Zhongwu Lai
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Co-authored papers 1
Shenghua Wen
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Co-authored papers 1
Mathew J Garnett
Wellcome Sanger Institute
Co-authored papers 1
Omid Tavana
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Co-authored papers 1
William McCoull
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Robert B Diebold
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Kate F Byth
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Terry MacIntyre
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Paula Lewis
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Alwin G Schuller
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Co-authored papers 1
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1
Patricia Jaaks
Wellcome Sanger Institute
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Martin Wild
Oncology R&D
Co-authored papers 1
David M Weinstock
Merck & Co.
Co-authored papers 1
Kathleen Burke
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Co-authored papers 1
Ricky W Johnstone
The University of Melbourne
Co-authored papers 1
Areya Tabatabai
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Eric Gangl
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Co-authored papers 1
Jonathan R Dry
Present Address: Tempus Labs Inc.
Co-authored papers 1
Andrea Newbold
Peter MacCallum Cancer Centre
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Release 1.2