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Author Details

Alvin Farrel
Children's Hospital of Philadelphia
2008
22
13
PMIDPaper TitleJournal TitlePublished Year
37292750Structural principles of peptide-centric Chimeric Antigen Receptor recognition guide therapeutic expansion.bioRxiv2023
37516886ROGUE: an R Shiny app for RNA sequencing analysis and biomarker discovery.BMC Bioinformatics2023
37938771Targeting of intracellular oncoproteins with peptide-centric CARs.Nature2023
38039376Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion.Sci Immunol2023
36381237Evaluation of the DLL3-targeting antibody-drug conjugate rovalpituzumab tesirine in preclinical models of neuroblastoma.Cancer Res Commun2022
36396952Pre-clinical investigation of astatine-211-parthanatine for high-risk neuroblastoma.Commun Biol2022
34732890Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.Nature2021
34893640Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction.Nat Commun2021
34469647Treatment of Relapsing HPV Diseases by Restored Function of Natural Killer Cells.N Engl J Med2021
32511347A SARS-CoV-2 Vaccination Strategy Focused on Population-Scale Immunity.bioRxiv2020
32835302Identification of SARS-CoV-2 Vaccine Epitopes Predicted to Induce Long-Term Population-Scale Immunity.Cell Rep Med2020
32714112A SARS-CoV-2 Vaccination Strategy Focused on Population-Scale Immunity.SSRN2020
32307821Limited antitumor activity of combined BET and MEK inhibition in neuroblastoma.Pediatr Blood Cancer2020
32256484Immunogenicity and Immune Silence in Human Cancer.Front Immunol2020
31693904Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design.Cell Rep2019
31672841YAP1 Mediates Resistance to MEK1/2 Inhibition in Neuroblastomas with Hyperactivated RAS Signaling.Cancer Res2019
31810498Combined innate and adaptive immunotherapy overcomes resistance of immunologically cold syngeneic murine neuroblastoma to checkpoint inhibition.J Immunother Cancer2019
28839204Effects of short indels on protein structure and function in human genomes.Sci Rep2017
28715997An efficient algorithm for improving structure-based prediction of transcription factor binding sites.BMC Bioinformatics2017
27307632Structure-based prediction of transcription factor binding specificity using an integrative energy function.Bioinformatics2016
19607800Characterization of DNA glycosylase activity by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.Anal Biochem2009
18485883Characterization of synthetic oligonucleotides containing biologically important modified bases by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.Anal Biochem2008
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Collaborators

Children's Hospital of Philadelphia
Co-authored papers 15
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 4
University of North Carolina at Charlotte
Co-authored papers 3
Children's Hospital of Philadelphia
Co-authored papers 3
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Co-authored papers 3
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 3
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 2
Co-authored papers 2
Children's Hospital of Philadelphia, USA. [2] Center for Childhood Cancer Research
Co-authored papers 2
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Co-authored papers 2
Children's Hospital Of Philadelphia
Co-authored papers 2
National Cancer Institute
Co-authored papers 2
Children's Hospital of Philadelphia.
Co-authored papers 2
University of Pennsylvania Perelman School of Medicine
Co-authored papers 2
Broad Institute of MIT and Harvard
Co-authored papers 1
Cancer Center, Texas Tech University Health Sciences Center School of Medicine
Co-authored papers 1
Co-authored papers 1
University Hospital Regensburg
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Northwestern University
Co-authored papers 1
Texas Children's Cancer Center, Baylor College of Medicine
Co-authored papers 1
Greehey Children's Cancer Research Institute
Co-authored papers 1
Children's Cancer Institute, Lowy Cancer Research Centre
Co-authored papers 1
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Baylor College of Medicine
Co-authored papers 1
Children's Hospital of Philadelphia
Co-authored papers 1
Greehey Children's Cancer Research Institute
Co-authored papers 1
Children's Hospital of Philadelphia
Co-authored papers 1
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Co-authored papers 1