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Author Details

Peter J Dempsey
University of Colorado
1968
150
57
PMIDPaper TitleJournal TitlePublished Year
36662859In situ modulation of intestinal organoid epithelial curvature through photoinduced viscoelasticity directs crypt morphogenesis.Sci Adv2023
36794954High Sox2 expression predicts taste lineage competency of lingual progenitors in vitro.Development2023
34915204Injury-Induced Cellular Plasticity Drives Intestinal Regeneration.Cell Mol Gastroenterol Hepatol2022
35288626Robo4 is constitutively shed by ADAMs from endothelial cells and the shed Robo4 functions to inhibit Slit3-induced angiogenesis.Sci Rep2022
33526513Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer.Cancer Res2021
32531190Rapid Crypt Cell Remodeling Regenerates the Intestinal Stem Cell Niche after Notch Inhibition.Stem Cell Reports2020
31792360Adaptation to inflammatory acidity through neutrophil-derived adenosine regulation of SLC26A3.Mucosal Immunol2020
32548863The Effect of Thiol Structure on Allyl Sulfide Photodegradable Hydrogels and their Application as a Degradable Scaffold for Organoid Passaging.Adv Mater2020
30827941Cellular Plasticity of Defa4<sup>Cre</sup>-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury.Cell Mol Gastroenterol Hepatol2019
29472497ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.J Exp Med2018
28739265Role of ADAM10 in intestinal crypt homeostasis and tumorigenesis.Biochim Biophys Acta Mol Cell Res2017
28462383Interdependency of EGF and GLP-2 Signaling in Attenuating Mucosal Atrophy in a Mouse Model of Parenteral Nutrition.Cell Mol Gastroenterol Hepatol2017
28230865ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation.Cell Death Dis2017
29166602Mucus Detachment by Host Metalloprotease Meprin β Requires Shedding of Its Inactive Pro-form, which Is Abrogated by the Pathogenic Protease RgpB.Cell Rep2017
27237596Are Facultative Reserve ISCs the Cellular Origin of Familial Small Intestinal Neuroendocrine Tumors?Gastroenterology2016
26667078ADAM Proteases and Gastrointestinal Function.Annu Rev Physiol2016
27868043Enterocyte progenitors can dedifferentiate to replace lost Lgr5<sup>+</sup> intestinal stem cells revealing that many different progenitor populations can regain stemness.Stem Cell Investig2016
25782989TPN-associated intestinal epithelial cell atrophy is modulated by TLR4/EGF signaling pathways.FASEB J2015
26283731Loss of ADAM17-Mediated Tumor Necrosis Factor Alpha Signaling in Intestinal Cells Attenuates Mucosal Atrophy in a Mouse Model of Parenteral Nutrition.Mol Cell Biol2015
26050928Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo.Stem Cell Reports2015
24639339Most lobular carcinoma in situ and atypical lobular hyperplasia diagnosed on core needle biopsy can be managed clinically with radiologic follow-up in a multidisciplinary setting.Cancer Med2014
25038433ADAM10 regulates Notch function in intestinal stem cells of mice.Gastroenterology2014
25031401N-cadherin promotes recruitment and migration of neural progenitor cells from the SVZ neural stem cell niche into demyelinated lesions.J Neurosci2014
24761961Jay J. Listinsky, MD, PhD.Radiology2014
22940630Constitutive α- and β-secretase cleavages of the amyloid precursor protein are partially coupled in neurons, but not in frequently used cell lines.Neurobiol Dis2013
24043629A Lactobacillus rhamnosus GG-derived soluble protein, p40, stimulates ligand release from intestinal epithelial cells to transactivate epidermal growth factor receptor.J Biol Chem2013
23377202Distinct TCR signaling pathways drive proliferation and cytokine production in T cells.Nat Immunol2013
22190634Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.Development2012
21617117TNF-α converting enzyme-mediated ErbB4 transactivation by TNF promotes colonic epithelial cell survival.Am J Physiol Gastrointest Liver Physiol2011
20015014Fluorescent substrates useful as high-throughput screening tools for ADAM9.Comb Chem High Throughput Screen2010
21131456The need for breast cancer screening in women undergoing elective breast surgery: an assessment of risk and risk factors for breast cancer in young women.Aesthet Surg J2010
20802254Conditional gene targeting in mouse pancreatic ÿ-Cells: analysis of ectopic Cre transgene expression in the brain.Diabetes2010
20530572Sequential and gamma-secretase-dependent processing of the betacellulin precursor generates a palmitoylated intracellular-domain fragment that inhibits cell growth.J Cell Sci2010
20156974ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo.J Exp Med2010
20403327TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation.Cell2010
20014014New ultrasound-based imaging technologies are claimed to avoid unnecessary breast biopsies, but what is an "unnecessary" image-guided needle biopsy of the breast?J Clin Ultrasound2010
19250983Epidermal growth factor receptor activation protects gastric epithelial cells from Helicobacter pylori-induced apoptosis.Gastroenterology2009
19601831ADAM10 as a therapeutic target for cancer and inflammation.Curr Pharm Des2009
18026834Mammographic features of triple receptor-negative primary breast cancers in young premenopausal women.Breast Cancer Res Treat2008
18687778Deficiency of TNFalpha converting enzyme (TACE/ADAM17) causes a lean, hypermetabolic phenotype in mice.Endocrinology2008
18289051ADAM10 as a target for anti-cancer therapy.Curr Pharm Biotechnol2008
18281553TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer.Clin Cancer Res2008
18359447Results of a survey on digital screening mammography: prevalence, efficiency, and use of ancillary diagnostic AIDS.J Am Coll Radiol2008
17910038Generation of novel, secreted epidermal growth factor receptor (EGFR/ErbB1) isoforms via metalloprotease-dependent ectodomain shedding and exosome secretion.J Cell Biochem2008
18180404Novel role of protein kinase C-delta Tyr 311 phosphorylation in vascular smooth muscle cell hypertrophy by angiotensin II.Hypertension2008
17245433Metalloproteases regulate T-cell proliferation and effector function via LAG-3.EMBO J2007
17895248The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events.J Biol Chem2007
17826054Utility of ultrasound and fine-needle aspiration biopsy of the axilla in the assessment of invasive lobular carcinoma of the breast.Am J Surg2007
17888773Diagnostic breast ultrasound: current status and future directions.Radiol Clin North Am2007
17371977Non-cell autonomous expression of TNF-alpha-converting enzyme ADAM17 is required for normal lymphocyte development.J Immunol2007
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Collaborators

Co-authored papers 28
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Co-authored papers 2
The Ohio State University College of Medicine
Co-authored papers 2
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Monash University
Co-authored papers 2
University of Colorado
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1
University of Colorado Denver at Anschutz Medical Campus
Co-authored papers 1
School of Public Health, University of Alabama at Birmingham
Co-authored papers 1
Dana-Farber Cancer Institute
Co-authored papers 1
Earle A. Chiles Research Institute, Providence Cancer Institute
Co-authored papers 1
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Co-authored papers 1
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Cardiovascular Institute, University of Colorado
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