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Author Details
Full Name
Patrick D Hsu
Affiliation
University of California berkeley
ORCID
Career Start Year
2009
Papers
32
H Index
22
Expertise
CM4AI Collaborator
Prashant Mali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36909524
Strategies for effectively modelling promoter-driven gene expression using transfer learning.
bioRxiv
2024
36217031
Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome.
Nat Biotechnol
2023
36949040
Checkpoint kinase 1/2 inhibition potentiates anti-tumoral immune response and sensitizes gliomas to immune checkpoint blockade.
Nat Commun
2023
37410700
The KDM6A-KMT2D-p300 axis regulates susceptibility to diverse coronaviruses by mediating viral receptor expression.
PLoS Pathog
2023
37310920
DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner.
PLoS Biol
2023
35879412
Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.
Nat Genet
2022
35552677
Translocon-associated Protein Subunit SSR3 Determines and Predicts Susceptibility to Paclitaxel in Breast Cancer and Glioblastoma.
Clin Cancer Res
2022
35981511
What are the current bottlenecks in developing and applying CRISPR technologies?
Cell Syst
2022
32511497
Test performance evaluation of SARS-CoV-2 serological assays.
medRxiv
2020
33346708
A Catalogue of Cas9 Orthologs to Advance Genome Engineering.
CRISPR J
2020
32855547
Evaluation of SARS-CoV-2 serology assays reveals a range of test performance.
Nat Biotechnol
2020
32584145
Programmable RNA Targeting Using CasRx in Flies.
CRISPR J
2020
32528131
Ribosomal protein S11 influences glioma response to TOP2 poisons.
Oncogene
2020
29551272
Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors.
Cell
2018
30241607
Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d.
Cell
2018
30054474
Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells.
Nat Commun
2018
30154463
Publisher Correction: Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells.
Nat Commun
2018
26875867
Structure and Engineering of Francisella novicida Cas9.
Cell
2016
27494557
Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity.
Mol Cell
2016
25494202
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.
Nature
2015
26068008
Delivery and Specificity of CRISPR-Cas9 Genome Editing Technologies for Human Gene Therapy.
Hum Gene Ther
2015
24529477
Crystal structure of Cas9 in complex with guide RNA and target DNA.
Cell
2014
24752079
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
Nat Biotechnol
2014
24906146
Development and applications of CRISPR-Cas9 for genome engineering.
Cell
2014
24557909
RNA-guided genome editing of mammalian cells.
Methods Mol Biol
2014
23287718
Multiplex genome engineering using CRISPR/Cas systems.
Science
2013
24157548
Genome engineering using the CRISPR-Cas9 system.
Nat Protoc
2013
23877069
Optical control of mammalian endogenous transcription and epigenetic states.
Nature
2013
23873081
DNA targeting specificity of RNA-guided Cas9 nucleases.
Nat Biotechnol
2013
23992846
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity.
Cell
2013
22896804
Dissecting neural function using targeted genome engineering technologies.
ACS Chem Neurosci
2012
19955359
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia.
J Neurosci
2009
1 - 32 of 32
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