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Author Details

Laura Z Rassenti
University of California San Diego
1985
183
68
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36624313Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome.Nat Med2023
37871223Expression signature of human endogenous retroviruses in chronic lymphocytic leukemia.Proc Natl Acad Sci U S A2023
34285341Polygenic risk score and risk of monoclonal B-cell lymphocytosis in caucasians and risk of chronic lymphocytic leukemia (CLL) in African Americans.Leukemia2022
35361793cyCombine allows for robust integration of single-cell cytometry datasets within and across technologies.Nat Commun2022
35418613High expression level of ROR1 and ROR1-signaling associates with venetoclax resistance in chronic lymphocytic leukemia.Leukemia2022
35747847B-cell Receptor Signaling Induced Metabolic Alterations in Chronic Lymphocytic Leukemia Can Be Partially Bypassed by <i>TP53</i> Abnormalities.Hemasphere2022
35903706Impact of the Types and Relative Quantities of IGHV Gene Mutations in Predicting Prognosis of Patients With Chronic Lymphocytic Leukemia.Front Oncol2022
35927489Molecular map of chronic lymphocytic leukemia and its impact on outcome.Nat Genet2022
35064090A large fraction of trisomy 12, 17p<sup>-</sup>, and 11q<sup>-</sup> CLL cases carry unidentified microdeletions of <i>miR-15a/16-1</i>.Proc Natl Acad Sci U S A2022
35020831Single-cell analysis reveals immune dysfunction from the earliest stages of CLL that can be reversed by ibrutinib.Blood2022
33097837Wnt5a enhances proliferation of chronic lymphocytic leukemia and ERK1/2 phosphorylation via a ROR1/DOCK2-dependent mechanism.Leukemia2021
33689703A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation.Cancer Cell2021
33604581Preneoplastic Alterations Define CLL DNA Methylome and Persist through Disease Progression and Therapy.Blood Cancer Discov2021
34939038Multifunctional barcoding with ClonMapper enables high-resolution study of clonal dynamics during tumor evolution and treatment.Nat Cancer2021
34686499Activation of <i>Notch</i> and <i>Myc</i> Signaling via B-cell-Restricted Depletion of <i>Dnmt3a</i> Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia.Cancer Res2021
34112698Longitudinal Single-Cell Dynamics of Chromatin Accessibility and Mitochondrial Mutations in Chronic Lymphocytic Leukemia Mirror Disease History.Cancer Discov2021
33171493miR-29 modulates CD40 signaling in chronic lymphocytic leukemia by targeting TRAF4: an axis affected by BCR inhibitors.Blood2021
33451349Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia.J Hematol Oncol2021
32938797Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect.Sci Transl Med2020
31992855NF-κB-p62-NRF2 survival signaling is associated with high ROR1 expression in chronic lymphocytic leukemia.Cell Death Differ2020
30443898SET alpha and SET beta mRNA isoforms in chronic lymphocytic leukaemia.Br J Haematol2019
31723042Dysregulation of different classes of tRNA fragments in chronic lymphocytic leukemia.Proc Natl Acad Sci U S A2019
31744508Genetic dynamics in untreated CLL patients with either stable or progressive disease: a longitudinal study.J Hematol Oncol2019
31473933Plasma B-Cell Maturation Antigen Levels are Elevated and Correlate with Disease Activity in Patients with Chronic Lymphocytic Leukemia.Target Oncol2019
31409670Cirmtuzumab blocks Wnt5a/ROR1 stimulation of NF-κB to repress autocrine STAT3 activation in chronic lymphocytic leukemia.Blood2019
31292113Developmental subtypes assessed by DNA methylation-iPLEX forecast the natural history of chronic lymphocytic leukemia.Blood2019
31018621HNRNPL Restrains <i>miR-155</i> Targeting of BUB1 to Stabilize Aberrant Karyotypes of Transformed Cells in Chronic Lymphocytic Leukemia.Cancers (Basel)2019
30712845A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion.Cancer Cell2019
30923040Activation of hedgehog signaling associates with early disease progression in chronic lymphocytic leukemia.Blood2019
31142838Growth dynamics in naturally progressing chronic lymphocytic leukaemia.Nature2019
30967392Efficacy results of a phase 2 trial of first-line idelalisib plus ofatumumab in chronic lymphocytic leukemia.Blood Adv2019
30568170Wnt5a causes ROR1 to complex and activate cortactin to enhance migration of chronic lymphocytic leukemia cells.Leukemia2019
27766619Dynamic changes in CCL3 and CCL4 plasma concentrations in patients with chronic lymphocytic leukaemia managed with observation.Br J Haematol2018
30242085<i>miR-125a</i> and <i>miR-34a</i> expression predicts Richter syndrome in chronic lymphocytic leukemia patients.Blood2018
29859176Phase I Trial: Cirmtuzumab Inhibits ROR1 Signaling and Stemness Signatures in Patients with Chronic Lymphocytic Leukemia.Cell Stem Cell2018
29872501Cirmtuzumab inhibits ibrutinib-resistant, Wnt5a-induced Rac1 activation and proliferation in mantle cell lymphoma.Oncotarget2018
30282833Splicing modulation sensitizes chronic lymphocytic leukemia cells to venetoclax by remodeling mitochondrial apoptotic dependencies.JCI Insight2018
29678828Wnt5a induces ROR1 to recruit DOCK2 to activate Rac1/2 in chronic lymphocytic leukemia.Blood2018
27890934EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia.Leukemia2017
28412730The long noncoding RNA, treRNA, decreases DNA damage and is associated with poor response to chemotherapy in chronic lymphocytic leukemia.Oncotarget2017
28465529Wnt5a induces ROR1 to complex with HS1 to enhance migration of chronic lymphocytic leukemia cells.Leukemia2017
28465528Wnt5a induces ROR1 to associate with 14-3-3ζ for enhanced chemotaxis and proliferation of chronic lymphocytic leukemia cells.Leukemia2017
28115735Leukemia-cell proliferation and disease progression in patients with early stage chronic lymphocytic leukemia.Leukemia2017
28923920<i>MicroRNA</i> dysregulation to identify therapeutic target combinations for chronic lymphocytic leukemia.Proc Natl Acad Sci U S A2017
28526063Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia.J Hematol Oncol2017
27904138Cirmtuzumab inhibits Wnt5a-induced Rac1 activation in chronic lymphocytic leukemia treated with ibrutinib.Leukemia2017
26848054The Dohner fluorescence in situ hybridization prognostic classification of chronic lymphocytic leukaemia (CLL): the CLL Research Consortium experience.Br J Haematol2016
30302201Dielectrophoretic recovery of DNA from plasma for the identification of chronic lymphocytic leukemia point mutations.Int J Hematol Oncol2016
26646452Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway.Oncotarget2016
26639181A complementary role of multiparameter flow cytometry and high-throughput sequencing for minimal residual disease detection in chronic lymphocytic leukemia: an European Research Initiative on CLL study.Leukemia2016
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Collaborators

Thomas J Kipps
University of California San Diego
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Donna Neuberg
Co-authored papers 32
Catherine J Wu
Co-authored papers 14
Gad Getz
Broad Institute of the Massachusetts Institute of Technology and Harvard
Co-authored papers 8
Karen Messer
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Co-authored papers 7
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German Cancer Research Center
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Stanford Cancer Institute, Stanford University
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National Cancer Institute, National Institutes of Health
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Lynn R Goldin
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University of California, USA Institute for Genomic Medicine
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Division of Epidemiology and Clinical Research, University of Minnesota
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The Ohio State University Comprehensive Cancer Center
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Angela Brooks-Wilson
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Institute for Genomic Medicine, University of California San Diego
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Amaro Taylor-Weiner
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Erin N Smith
Department of Pediatrics and Rady's Children's Hospital, University of California
Co-authored papers 4
Arthur Weiss
University of California san francisco
Co-authored papers 4
Steven P Briggs
Co-authored papers 3
Torsten Haferlach
Taussig Cancer Institute, Cleveland Clinic
Co-authored papers 3
Alexander Kohlmann
Oncology R&D
Co-authored papers 3
Dimitri Livitz
Co-authored papers 3
Alexander Meissner
Co-authored papers 3
Christopher DeBoever
Stanford University
Co-authored papers 3
Robin Fo??
Sapienza University.
Co-authored papers 3
Zhouxin Shen
Co-authored papers 3
Hagop Kantarjian
The University of Texas MD Anderson Cancer Center
Co-authored papers 3
Chip Stewart
Broad Institute of MIT and Harvard
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Release 1.2