Author details

Full Name

Alexei A Aravin

Affiliation

ORCID

Career Start Year

1998

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37492097	Pervasive SUMOylation of heterochromatin and piRNA pathway proteins.		2023
37999956	SUMOylation of Bonus, the homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes.		2023
37998364	Impact of Germline Depletion of Bonus on Chromatin State in Ovaries.		2023
37723298	A maternally programmed intergenerational mechanism enables male offspring to make piRNAs from Y-linked precursor RNAs in Drosophila.		2023
37645991	SUMOylation of Bonus, the homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes.		2023
37875112	Maternally inherited siRNAs initiate piRNA cluster formation.		2023
37094066	Bacterial Argonaute nucleases reveal different modes of DNA targeting in vitro and in vivo.		2023
37059098	Genetic control of a sex-specific piRNA program.		2023
37102866	Bacterial Argonaute Proteins Aid Cell Division in the Presence of Topoisomerase Inhibitors in Escherichia coli.		2023
35978060	Author Correction: Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity.	Nature Communications	2022
35941106	Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity.	Nature Communications	2022
34473737	RDC complex executes a dynamic piRNA program during Drosophila spermatogenesis to safeguard male fertility.	PLoS Genetics	2021
33744962	A programmable pAgo nuclease with universal guide and target specificity from the mesophilic bacterium Kurthia massiliensis.	Nucleic Acids Research	2021
34210982	Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex.	Nat Commun	2021
33985970	piRNA-mediated gene regulation and adaptation to sex-specific transposon expression in male germline.	Genes and Development	2021
34624214	Transposon-taming piRNAs in the germline: Where do they come from?	Molecular Cell	2021
33164748	Repression of interrupted and intact rDNA by the SUMO pathway in .	eLife	2020
31901448	The SUMO Ligase Su(var)2-10 Controls Hetero- and Euchromatic Gene Expression via Establishing H3K9 Trimethylation and Negative Feedback Regulation.	Molecular Cell	2020
31901446	Su(var)2-10 and the SUMO Pathway Link piRNA-Guided Target Recognition to Chromatin Silencing.	Molecular Cell	2020
32013676	Genome-wide DNA sampling by Ago nuclease from the cyanobacterium .	RNA Biology	2020
33584811	Genes and the piRNA Pathway in Speciation and Reproductive Isolation of .	Frontiers in Genetics	2020
32601474	Pachytene piRNAs as beneficial regulators or a defense system gone rogue.	Nature Genetics	2020
32731256	DNA targeting and interference by a bacterial Argonaute nuclease.	Nature	2020
33333714	Recognition of double-stranded DNA by the Rhodobacter sphaeroides Argonaute protein.	Biochemical and Biophysical Research Communications	2020
30788506	piRNA silencing contributes to interspecies hybrid sterility and reproductive isolation in Drosophila melanogaster.	Nucleic Acids Research	2019
31540910	The control of gene expression and cell identity by H3K9 trimethylation.	Development (Cambridge)	2019
31114878	Programmable DNA cleavage by Ago nucleases from mesophilic bacteria Clostridium butyricum and Limnothrix rosea.	Nucleic Acids Research	2019
29738683	Argonaute Proteins and Mechanisms of RNA Interference in Eukaryotes and Prokaryotes.	Biochemistry (Moscow)	2018
30514832	DNA interference and beyond: structure and functions of prokaryotic Argonaute proteins.	Nature Communications	2018
29996105	Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.	Cell Rep	2018
30563906	The Expanded Universe of Prokaryotic Argonaute Proteins.	mBio	2018
28436983	Stable Polycomb-dependent transgenerational inheritance of chromatin states in Drosophila.	Nature Genetics	2017
28964526	piRNA Biogenesis in Drosophila melanogaster.	Trends in Genetics	2017
27036967	Splicing-independent loading of TREX on nascent RNA is required for efficient expression of dual-strand piRNA clusters in Drosophila.	Genes and Development	2016
27292797	Cutoff Suppresses RNA Polymerase II Termination to Ensure Expression of piRNA Precursors.	Mol Cell	2016
26279574	MIWI2 and MILI Have Differential Effects on piRNA Biogenesis and DNA Methylation.	Cell Reports	2015
25805138	Pitfalls of mapping high-throughput sequencing data to repetitive sequences: Piwi's genomic targets still not identified.	Dev Cell	2015
26659182	The histone chaperone CAF-1 safeguards somatic cell identity.	Nature	2015
26120554	Non-Coding RNAs in Transcriptional Regulation: The review for .		2015
26295961	Aub and Ago3 Are Recruited to Nuage through Two Mechanisms to Form a Ping-Pong Complex Assembled by Krimper.	Mol Cell	2015
26159654	Erratum: MORC1 represses transposable elements in the mouse male germline.	Nat Commun	2015
25085419	Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing.	Genes Dev	2014
25503965	MORC1 represses transposable elements in the mouse male germline.	Nat Commun	2014
24178556	A framework for piRNA cluster manipulation.	Methods in Molecular Biology	2014
24467990	To be or not to be a piRNA: genomic origin and processing of piRNAs.		2014
24589774	Small but sturdy: small RNAs in cellular memory and epigenetics.	Genes and Development	2014
25199836	A transgenerational process defines piRNA biogenesis in Drosophila virilis.	Cell Reports	2014
25030694	Two waves of de novo methylation during mouse germ cell development.	Genes and Development	2014
24939875	piRNA pathway targets active LINE1 elements to establish the repressive H3K9me3 mark in germ cells.	Genes and Development	2014
24836995	Prokaryotic Argonautes defend genomes against invasive DNA.	Trends in Biochemical Sciences	2014