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Author Details

Timothy E Sweeney
Inflammatix Inc.
1989
79
28
PMIDPaper TitleJournal TitlePublished Year
36692131Multisite validation of a host response signature for predicting likelihood of bacterial and viral infections in patients with suspected influenza.Eur J Clin Invest2023
37641125A machine learning classifier using 33 host immune response mRNAs accurately distinguishes viral and non-viral acute respiratory illnesses in nasal swab samples.Genome Med2023
37214996Defining critical illness using immunological endotypes in patients with and without of sepsis: A cohort study.Res Sq2023
37474944Defining critical illness using immunological endotypes in patients with and without sepsis: a cohort study.Crit Care2023
35134876Diagnostic Host Gene Expression Analysis by Quantitative Reverse Transcription Loop-Mediated Isothermal Amplification to Discriminate between Bacterial and Viral Infections.Clin Chem2022
35467566Prospective validation of a transcriptomic severity classifier among patients with suspected acute infection and sepsis in the emergency department.Eur J Emerg Med2022
35819783Evaluation of a Multivalent Transcriptomic Metric for Diagnosing Surgical Sepsis and Estimating Mortality Among Critically Ill Patients.JAMA Netw Open2022
35715504Redefining critical illness.Nat Med2022
36543117A robust host-response-based signature distinguishes bacterial and viral infections across diverse global populations.Cell Rep Med2022
36125356A 29-MRNA HOST RESPONSE WHOLE-BLOOD SIGNATURE IMPROVES PREDICTION OF 28-DAY MORTALITY AND 7-DAY INTENSIVE CARE UNIT CARE IN ADULTS PRESENTING TO THE EMERGENCY DEPARTMENT WITH SUSPECTED ACUTE INFECTION AND/OR SEPSIS.Shock2022
35916912A new possibility: gene-expression-based diagnostics for presymptomatic diagnosis of hospital-acquired infections.Intensive Care Med2022
35042868A 6-mRNA host response classifier in whole blood predicts outcomes in COVID-19 and other acute viral infections.Sci Rep2022
35173224A robust gene expression signature for NASH in liver expression data.Sci Rep2022
33201004Validation of Inflammopathic, Adaptive, and Coagulopathic Sepsis Endotypes in Coronavirus Disease 2019.Crit Care Med2021
33883455Gene Expression-Based Diagnosis of Infections in Critically Ill Patients-Prospective Validation of the SepsisMetaScore in a Longitudinal Severe Trauma Cohort.Crit Care Med2021
33883456The authors reply.Crit Care Med2021
33591001Sepsis Subclasses: A Framework for Development and Interpretation.Crit Care Med2021
34442377The Optimization and Biological Significance of a 29-Host-Immune-mRNA Panel for the Diagnosis of Acute Infections and Sepsis.J Pers Med2021
34671746A Transcriptomic Severity Metric That Predicts Clinical Outcomes in Critically Ill Surgical Sepsis Patients.Crit Care Explor2021
34374835Transcriptional markers in response to hydrocortisone in sepsis in ADRENAL: a step toward precision medicine.Intensive Care Med2021
34679598A Multi-mRNA Prognostic Signature for Anti-TNFα Therapy Response in Patients with Inflammatory Bowel Disease.Diagnostics (Basel)2021
34158514Prospective validation of an 11-gene mRNA host response score for mortality risk stratification in the intensive care unit.Sci Rep2021
34120332A host transcriptomic signature for identification of respiratory viral infections in the community.Eur J Clin Invest2021
34142256A 29-mRNA host response test from blood accurately distinguishes bacterial and viral infections among emergency department patients.Intensive Care Med Exp2021
34166284A Novel 29-Messenger RNA Host-Response Assay From Whole Blood Accurately Identifies Bacterial and Viral Infections in Patients Presenting to the Emergency Department With Suspected Infections: A Prospective Observational Study.Crit Care Med2021
33156120External Corroboration That Corticosteroids May Be Harmful to Septic Shock Endotype A Patients.Crit Care Med2021
32132525A generalizable 29-mRNA neural-network classifier for acute bacterial and viral infections.Nat Commun2020
33374697A 33-mRNA Classifier Is Able to Produce Inflammopathic, Adaptive, and Coagulopathic Endotypes with Prognostic Significance: The Outcomes of Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in the Early Treatment of Sepsis (ORANGES) Trial.J Pers Med2020
33297498A Multi-mRNA Host-Response Molecular Blood Test for the Diagnosis and Prognosis of Acute Infections and Sepsis: Proceedings from a Clinical Advisory Panel.J Pers Med2020
33038161Hunting for Genes Linked to Risk of, Not From, Bloodstream Infection.Crit Care Med2020
33437935Transcriptomic similarities and differences in host response between SARS-CoV-2 and other viral infections.iScience2020
32685595Cost Impact Model of a Novel Multi-mRNA Host Response Assay for Diagnosis and Risk Assessment of Acute Respiratory Tract Infections and Sepsis in the Emergency Department.J Health Econ Outcomes Res2020
30699342A 20-Gene Set Predictive of Progression to Severe Dengue.Cell Rep2019
31908991Pilot study of a novel serum mRNA gene panel for diagnosis of acute septic arthritis.World J Orthop2019
31446810Diagnosis of bacterial sepsis: why are tests for bacteremia not sufficient?Expert Rev Mol Diagn2019
31043466Diagnosing and Managing Sepsis by Probing the Host Response to Infection: Advances, Opportunities, and Challenges.J Clin Microbiol2019
29337789Multicohort Analysis of Whole-Blood Gene Expression Data Does Not Form a Robust Diagnostic for Acute Respiratory Distress Syndrome.Crit Care Med2018
30646264Assessment of Validity of a Blood-Based 3-Gene Signature Score for Progression and Diagnosis of Tuberculosis, Disease Severity, and Treatment Response.JAMA Netw Open2018
28419265Validation of the Sepsis MetaScore for Diagnosis of Neonatal Sepsis.J Pediatric Infect Dis Soc2018
29449546A community approach to mortality prediction in sepsis via gene expression analysis.Nat Commun2018
29537985Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters.Crit Care Med2018
29511207Author Correction: Circulating Biomarkers to Identify Responders in Cardiac Cell therapy.Sci Rep2018
29367465Inflammatory macrophage-associated 3-gene signature predicts subclinical allograft injury and graft survival.JCI Insight2018
27681387Benchmarking Sepsis Gene Expression Diagnostics Using Public Data.Crit Care Med2017
28084830Simplification of a Septic Shock Endotyping Strategy for Clinical Application.Am J Respir Crit Care Med2017
28324666Gene Expression Analysis to Assess the Relevance of Rodent Models to Human Lung Injury.Am J Respir Cell Mol Biol2017
28291107The authors reply.Crit Care Med2017
28212246The authors reply.Crit Care Med2017
28212222Septic Cardiomyopathy: Getting to the Heart of the Matter.Crit Care Med2017
28991828Pediatric Sepsis Endotypes Among Adults With Sepsis.Crit Care Med2017
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