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Author Details

Ivy D Moffat
University of Toronto
2004
28
18
PMIDPaper TitleJournal TitlePublished Year
37195416Per- and polyfluoroalkyl substances (PFAS) in mixtures show additive effects on transcriptomic points of departure in human liver spheroids.Toxicol Sci2023
34453843Potency Ranking of Per- and Polyfluoroalkyl Substances Using High-Throughput Transcriptomic Analysis of Human Liver Spheroids.Toxicol Sci2021
33772556High-Throughput Transcriptomic Analysis of Human Primary Hepatocyte Spheroids Exposed to Per- and Polyfluoroalkyl Substances as a Platform for Relative Potency Characterization.Toxicol Sci2021
28086803Compendium of TCDD-mediated transcriptomic response datasets in mammalian model systems.BMC Genomics2017
25529477Transcriptional profiling of rat hypothalamus response to 2,3,7,8-tetrachlorodibenzo-ρ-dioxin.Toxicology2015
26425668A predictive toxicogenomics signature to classify genotoxic versus non-genotoxic chemicals in human TK6 cells.Data Brief2015
26232522Transcriptional profiling of rat white adipose tissue response to 2,3,7,8-tetrachlorodibenzo-ρ-dioxin.Toxicol Appl Pharmacol2015
26041267Neurotoxicity may be an overlooked consequence of benzo[a]pyrene exposure that is relevant to human health risk assessment.Mutat Res Rev Mutat Res2015
25944780Technical guide for applications of gene expression profiling in human health risk assessment of environmental chemicals.Regul Toxicol Pharmacol2015
25733247Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK6 cells.Environ Mol Mutagen2015
25605026Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water.Crit Rev Toxicol2015
25605027Integrating toxicogenomics into human health risk assessment: lessons learned from the benzo[a]pyrene case study.Crit Rev Toxicol2015
25467400Cross-species transcriptomic analysis elucidates constitutive aryl hydrocarbon receptor activity.BMC Genomics2014
23146762Gene expression profiling to identify potentially relevant disease outcomes and support human health risk assessment for carbon black nanoparticle exposure.Toxicology2013
23458726Preparation of archival formalin-fixed paraffin-embedded mouse liver samples for use with the Agilent gene expression microarray platform.J Pharmacol Toxicol Methods2013
21215274Hepatic transcriptomic responses to TCDD in dioxin-sensitive and dioxin-resistant rats during the onset of toxicity.Toxicol Appl Pharmacol2011
21760882mRNA levels in control rat liver display strain-specific, hereditary, and AHR-dependent components.PLoS One2011
20420666Aryl hydrocarbon receptor (AHR)-regulated transcriptomic changes in rats sensitive or resistant to major dioxin toxicities.BMC Genomics2010
18394668Genome-wide effects of acute progressive feed restriction in liver and white adipose tissue.Toxicol Appl Pharmacol2008
18796159Transcriptomic responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in liver: comparison of rat and mouse.BMC Genomics2008
18465118Patterns of dioxin-altered mRNA expression in livers of dioxin-sensitive versus dioxin-resistant rats.Arch Toxicol2008
17698510microRNAs in adult rodent liver are refractory to dioxin treatment.Toxicol Sci2007
17636048Aryl hydrocarbon receptor splice variants in the dioxin-resistant rat: tissue expression and transactivational activity.Mol Pharmacol2007
16214954Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries.Mol Pharmacol2006
16466705Evaluation of various housekeeping genes for their applicability for normalization of mRNA expression in dioxin-treated rats.Chem Biol Interact2006
16497791Differential expression profiling of the hepatic proteome in a rat model of dioxin resistance: correlation with genomic and transcriptomic analyses.Mol Cell Proteomics2006
15993909Toxicological implications of polymorphisms in receptors for xenobiotic chemicals: the case of the aryl hydrocarbon receptor.Toxicol Appl Pharmacol2005
15358164Dioxin-responsive AHRE-II gene battery: identification by phylogenetic footprinting.Biochem Biophys Res Commun2004
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Collaborators

University of Toronto
Co-authored papers 17
Department of Food Hygiene and Environmental Health, University of Helsinki
Co-authored papers 17
University of California los angeles
Co-authored papers 16
University of Ottawa
Co-authored papers 10
University of Helsinki
Co-authored papers 7
University Health Network
Co-authored papers 5
University of California los angeles
Co-authored papers 4
Biomedicine Discovery Institute, Monash University
Co-authored papers 4
University of Jyvaskyla
Co-authored papers 4
Ontario Institute for Cancer Research
Co-authored papers 3
Ontario Institute for Cancer Research, University of Toronto
Co-authored papers 3
University Avenue
Co-authored papers 3
Co-authored papers 3
University of Toronto
Co-authored papers 3
University of British Columbia
Co-authored papers 2
Ontario Institute for Cancer Research
Co-authored papers 2
College of Veterinary Medicine, Kansas State University
Co-authored papers 2
Ontario Institute for Cancer Research, University Avenue
Co-authored papers 2
Ontario Institute for Cancer Research
Co-authored papers 2
University of Toronto.
Co-authored papers 1
Istituto di Ricerche Farmacologiche Mario Negri IRCCS
Co-authored papers 1
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University of Groningen, University Medical Center Groningen
Co-authored papers 1
IRCCS-Istituto di Ricerche Farmacologiche Mario Negri
Co-authored papers 1
Big Data Institute, University of Oxford
Co-authored papers 1
Finnish Institute for Health and Welfare (THL)
Co-authored papers 1
Ontario Institute for Cancer Research
Co-authored papers 1
National Institute of Environmental Health Sciences
Co-authored papers 1
The Hospital for Sick Children
Co-authored papers 1
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