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Author Details

Jan Rozman
German Center for Diabetes Research (DZD)
2003
117
37
PMIDPaper TitleJournal TitlePublished Year
36349687Identifying causal serum protein-cardiometabolic trait relationships using whole genome sequencing.Hum Mol Genet2023
37603466The negative adipogenesis regulator <i>Dlk1</i> is transcriptionally regulated by <i>Ifrd1</i> (TIS7) and translationally by its orthologue <i>Ifrd2</i> (SKMc15).Elife2023
37326672A review of standardized high-throughput cardiovascular phenotyping with a link to metabolism in mice.Mamm Genome2023
37210431Introduction to Mammalian Genome special issue: cardiovascular disease in the Mammalian Genome.Mamm Genome2023
37294348Comprehensive ECG reference intervals in C57BL/6N substrains provide a generalizable guide for cardiac electrophysiology studies in mice.Mamm Genome2023
36424672Dietary digestible carbohydrates are associated with higher prevalence of asthma in humans and with aggravated lung allergic inflammation in mice.Allergy2023
34328547INFRAFRONTIER quality principles in systemic phenotyping.Mamm Genome2022
35645339Comprehensive Transcriptional Profiling and Mouse Phenotyping Reveals Dispensable Role for Adipose Tissue Selective Long Noncoding RNA <i>Gm15551</i>.Noncoding RNA2022
36369285Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.Nat Commun2022
34812516Genes controlling skeletal muscle glucose uptake and their regulation by endurance and resistance exercise.J Cell Biochem2022
34287642Activation of the integrated stress response confers vulnerability to mitoribosome-targeting antibiotics in melanoma.J Exp Med2021
33767445Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice.Nature2021
33727559Author Correction: Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice.Nat Commun2021
33501434Bispecific antibody neutralizes circulating SARS-CoV-2 variants, prevents escape and protects mice from disease.bioRxiv2021
34750991Characterising a homozygous two-exon deletion in UQCRH: comparing human and mouse phenotypes.EMBO Mol Med2021
34043061A comprehensive phenotypic characterization of a whole-body Wdr45 knock-out mouse.Mamm Genome2021
34039610Disruption of paternal circadian rhythm affects metabolic health in male offspring via nongerm cell factors.Sci Adv2021
34345019Publisher Correction: Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice.Nature2021
32780722Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity.J Clin Invest2020
32060626A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes.Mamm Genome2020
31929527High-throughput discovery of genetic determinants of circadian misalignment.PLoS Genet2020
32005798Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice.Nat Commun2020
31941883Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification.Nat Commun2020
33370286Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density.PLoS Genet2020
33127955PAX6 mutation alters circadian rhythm and β cell function in mice without affecting glucose tolerance.Commun Biol2020
30557699A mouse model for intellectual disability caused by mutations in the X-linked 2'â¿¿Oâ¿¿methyltransferase Ftsj1 gene.Biochim Biophys Acta Mol Basis Dis2019
31111503Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.J Inherit Metab Dis2019
30530468Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy.EMBO Mol Med2019
28695538Fgf9 <sup>Y162C</sup> Mutation Alters Information Processing and Social Memory in Mice.Mol Neurobiol2018
30054579Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain.Sci Rep2018
30100055The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?Biochem Biophys Res Commun2018
28483715Analysis of locomotor behavior in the German Mouse Clinic.J Neurosci Methods2018
28373690A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice.Mol Psychiatry2018
29467291Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice.Proc Natl Acad Sci U S A2018
29659570Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data.PLoS Biol2018
28966146Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.Behav Brain Res2018
29348434Identification of genetic elements in metabolism by high-throughput mouse phenotyping.Nat Commun2018
27914009Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms.Mol Neurobiol2017
28112681Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance.J Clin Invest2017
28271032Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice.Mol Metab2017
28235645Modification of the fatty acid composition of an obesogenic diet improves the maternal and placental metabolic environment in obese pregnant mice.Biochim Biophys Acta Mol Basis Dis2017
28145422Proximate causes for diet-induced obesity in laboratory mice: a case study.Eur J Clin Nutr2017
29229863Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo.Proc Natl Acad Sci U S A2017
29117557The Role of Eif6 in Skeletal Muscle Homeostasis Revealed by Endurance Training Co-expression Networks.Cell Rep2017
28702329Metformin causes a futile intestinal-hepatic cycle which increases energy expenditure and slows down development of a type 2 diabetes-like state.Mol Metab2017
28645892<i>Meis1</i>: effects on motor phenotypes and the sensorimotor system in mice.Dis Model Mech2017
28869421A systemic view on the distribution of diet-derived methanol and hepatic acetone in mice.J Breath Res2017
28818080Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1 <sup>I27N</sup> mutant mice.J Biomed Sci2017
28761067Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice.Nat Commun2017
28546545Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression.Sci Rep2017
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Collaborators

Martin Hrab?? de Angelis
German Center for Diabetes Research (DZD e.V.)
Co-authored papers 95
Martin Klingenspor
Technical University of Munich
Co-authored papers 74
Helmut Fuchs
Institute of Experimental Genetics, German Mouse Clinic
Co-authored papers 73
Valerie Gailus-Durner
Institute of Experimental Genetics, German Mouse Clinic
Co-authored papers 69
Wolfgang Wurst
Institute of Developmental Genetics, German Research Center for Environmental Health
Co-authored papers 43
Sabine M H??lter
German Research Centre for Environmental Health
Co-authored papers 36
Tania Sorg
Universite de Strasbourg, CNRS, INSERM, Institut de La Clinique de La Souris
Co-authored papers 7
Yann Herault
Institut Clinique de la Souris (ICS), Universite de Strasbourg, CNRS, INSERM
Co-authored papers 7
Nicole Ehrhardt
University of Washington
Co-authored papers 7
Ann-Marie Mallon
The Turing Institute
Co-authored papers 6
Sara Wells
Mary Lyon Centre at Medical Research Council
Co-authored papers 6
Ann M Flenniken
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 6
Colin McKerlie
The Hospital for Sick Children
Co-authored papers 6
Lauryl M J Nutter
The Hospital for Sick Children
Co-authored papers 5
Steve D M Brown
Mary Lyon Centre Harwell Science and Innovation Campus Oxfordshire UK.
Co-authored papers 5
Kent C Lloyd
University of California davis
Co-authored papers 4
Luis Santos
The Turing Institute
Co-authored papers 4
Jacqueline K White
Wellcome Trust Sanger Institute
Co-authored papers 4
Terrence F Meehan
European Bioinformatics Institute
Co-authored papers 3
Robert E Braun
University of Maine
Co-authored papers 3
George Kollias
Co-authored papers 3
Theodora Hatziioannou
The Rockefeller University
Co-authored papers 3
Paul D Bieniasz
The Rockefeller University
Co-authored papers 3
Helen Parkinson
European Bioinformatics Institute
Co-authored papers 3
Je Kyung Seong
Seoul National University
Co-authored papers 3
Stephen A Murray
Columbia University.
Co-authored papers 3
Glauco P Tocchini-Valentini
Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR)
Co-authored papers 3
Pamela J Bjorkman
Co-authored papers 3
Jeremy Mason
European Molecular Biology Laboratory - European Bioinformatics Institute
Co-authored papers 3
Simon Greenaway
Harwell Institute
Co-authored papers 2
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