|
| 36862515 | COVID-19 convalescent plasma boosts early antibody titer and does not influence the adaptive immune response. | JCI Insight | 2023 |
| 37599009 | Selection of a statistical analysis method for the Glasgow Outcome Scale-Extended endpoint for estimating the probability of favorable outcome in future severe TBI clinical trials. | Stat Med | 2023 |
| 37009524 | Statistical assessment of the prognostic and the predictive value of biomarkers-A biomarker assessment framework with applications to traumatic brain injury biomarker studies. | Res Methods Med Health Sci | 2023 |
| 35273066 | Brain Oxygen Optimization in Severe Traumatic Brain Injury (BOOST-3): a multicentre, randomised, blinded-endpoint, comparative effectiveness study of brain tissue oxygen and intracranial pressure monitoring versus intracranial pressure alone. | BMJ Open | 2022 |
| 35544137 | Comparison of Bayesian vs Frequentist Adaptive Trial Design in the Stroke Hyperglycemia Insulin Network Effort Trial. | JAMA Netw Open | 2022 |
| 35786002 | An adaptive clinical trial design to identify the target dose of tenecteplase for treatment of acute pulmonary embolism. | Clin Trials | 2022 |
| 33319651 | Progesterone Treatment Does Not Decrease Serum Levels of Biomarkers of Glial and Neuronal Cell Injury in Moderate and Severe Traumatic Brain Injury Subjects: A Secondary Analysis of the Progesterone for Traumatic Brain Injury, Experimental Clinical Treatment (ProTECT) III Trial. | J Neurotrauma | 2021 |
| 34407339 | Early Convalescent Plasma for High-Risk Outpatients with Covid-19. | N Engl J Med | 2021 |
| 34278192 | Coagulation markers and functional outcome in acute ischemic stroke: Impact of intensive versus standard hyperglycemia control. | Res Pract Thromb Haemost | 2021 |
| 32568642 | Efficacy of Clopidogrel for Prevention of Stroke Based on <i>CYP2C19</i> Allele Status in the POINT Trial. | Stroke | 2020 |
| 32664792 | Sliding Scoring of the Glasgow Outcome Scale-Extended as Primary Outcome in Traumatic Brain Injury Trials. | J Neurotrauma | 2020 |
| 32897310 | Outcomes of Intensive Systolic Blood Pressure Reduction in Patients With Intracerebral Hemorrhage and Excessively High Initial Systolic Blood Pressure: Post Hoc Analysis of a Randomized Clinical Trial. | JAMA Neurol | 2020 |
| 31104615 | Recommendations for the Establishment of Stroke Systems of Care: A 2019 Update. | Stroke | 2019 |
| 31774955 | Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus. | N Engl J Med | 2019 |
| 31490536 | Assessment of the End Point Adjudication Process on the Results of the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial: A Secondary Analysis. | JAMA Netw Open | 2019 |
| 31334795 | Intensive vs Standard Treatment of Hyperglycemia and Functional Outcome in Patients With Acute Ischemic Stroke: The SHINE Randomized Clinical Trial. | JAMA | 2019 |
| 31070807 | Bayesian hierarchical EMAX model for dose-response in early phase efficacy clinical trials. | Stat Med | 2019 |
| 31138085 | Serum NfL (Neurofilament Light Chain) Levels and Incident Stroke in Adults With Diabetes Mellitus. | Stroke | 2019 |
| 29789395 | Blood Pressure-Attained Analysis of ATACH 2 Trial. | Stroke | 2018 |
| 29766750 | Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA. | N Engl J Med | 2018 |
| 29085638 | The life cycles of six multi-center adaptive clinical trials focused on neurological emergencies developed for the Advancing Regulatory Science initiative of the National Institutes of Health and US Food and Drug Administration: Case studies from the Adaptive Designs Accelerating Promising Treatments Into Trials Project. | SAGE Open Med | 2017 |
| 28135827 | A conceptual model for the development process of confirmatory adaptive clinical trials within an emergency research network. | Clin Trials | 2017 |
| 27306921 | Hyperbaric oxygen brain injury treatment (HOBIT) trial: a multifactor design with response adaptive randomization and longitudinal modeling. | Pharm Stat | 2016 |
| 27473126 | Attitudes and opinions regarding confirmatory adaptive clinical trials: a mixed methods analysis from the Adaptive Designs Accelerating Promising Trials into Treatments (ADAPT-IT) project. | Trials | 2016 |
| 27276234 | Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage. | N Engl J Med | 2016 |
| 25933921 | Clinical trialist perspectives on the ethics of adaptive clinical trials: a mixed-methods analysis. | BMC Med Ethics | 2015 |
| 26622163 | Reflections on the Adaptive Designs Accelerating Promising Trials Into Treatments (ADAPT-IT) Process-Findings from a Qualitative Study. | Clin Res Regul Aff | 2015 |
| 26693186 | Assessment of Emergency Medical Services in the Ashanti Region of Ghana. | Ghana Med J | 2015 |
| 26083566 | Patient Engagement in Neurological Clinical Trials Design: A Conference Summary. | Clin Transl Sci | 2015 |
| 25896893 | Neuroprotection in acute brain injury: an up-to-date review. | Crit Care | 2015 |
| 23506245 | The Stroke Hyperglycemia Insulin Network Effort (SHINE) trial protocol: a randomized, blinded, efficacy trial of standard vs. intensive hyperglycemia management in acute stroke. | Int J Stroke | 2014 |
| 25493974 | Very early administration of progesterone for acute traumatic brain injury. | N Engl J Med | 2014 |
| 24968105 | The empirical foundations of telemedicine interventions for chronic disease management. | Telemed J E Health | 2014 |
| 24925082 | Screen failure data in clinical trials: Are screening logs worth it? | Clin Trials | 2014 |
| 24613595 | A systematic review and critical appraisal of quality measures for the emergency care of acute ischemic stroke. | Ann Emerg Med | 2014 |
| 23851207 | Spinal cord injury neuroprotection and the promise of flexible adaptive clinical trials. | World Neurosurg | 2014 |
| 23879752 | Platelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and design. | Int J Stroke | 2013 |
| 24076337 | High-dose albumin treatment for acute ischaemic stroke (ALIAS) Part 2: a randomised, double-blind, phase 3, placebo-controlled trial. | Lancet Neurol | 2013 |
| 22335736 | Intramuscular versus intravenous therapy for prehospital status epilepticus. | N Engl J Med | 2012 |
| 22994221 | Impact of regional pre-hospital emergency medical services in treatment of patients with acute ischemic stroke. | Ann N Y Acad Sci | 2012 |
| 22435868 | Optimizing clinical operations as part of a global emergency medicine initiative in Kumasi, Ghana: application of Lean manufacturing principals to low-resource health systems. | Acad Emerg Med | 2012 |
| 22424650 | An overview of the adaptive designs accelerating promising trials into treatments (ADAPT-IT) project. | Ann Emerg Med | 2012 |
| 20576390 | Thrombolytic therapy for acute ischemic stroke beyond three hours. | J Emerg Med | 2011 |
| 21546491 | The Albumin in Acute Stroke Part 1 Trial: an exploratory efficacy analysis. | Stroke | 2011 |
| 20335563 | Swift or sure?: The acceptable rate of neurovascular mimics among IV tPA-treated patients. | Neurology | 2010 |
| 21040112 | Recruitment and retention of patients into emergency medicine clinical trials. | Acad Emerg Med | 2010 |
| 21040107 | Safety of intravenous thrombolytic use in four emergency departments without acute stroke teams. | Acad Emerg Med | 2010 |
| 21036295 | NIH Roundtable on Opportunities to Advance Research on Neurologic and Psychiatric Emergencies. | Ann Emerg Med | 2010 |
| 21036294 | NIH Roundtable on Emergency Trauma Research. | Ann Emerg Med | 2010 |
| 19478518 | Neurological emergencies. | Front Neurol Neurosci | 2009 |