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Author Details

Alastair Davies
University of British Columbia
2008
24
19
PMIDPaper TitleJournal TitlePublished Year
37470668The Transcriptional and Epigenetic Landscape of Cancer Cell Lineage Plasticity.Cancer Discov2023
35477723ASCL1 activates neuronal stem cell-like lineage programming through remodeling of the chromatin landscape in prostate cancer.Nat Commun2022
34128829Targeting androgen receptor signaling: a historical perspective.Endocr Relat Cancer2021
33741908CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer.Nat Commun2021
33758253Distinct DNA methylation patterns associated with treatment resistance in metastatic castration resistant prostate cancer.Sci Rep2021
34489572An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer.Nat Cell Biol2021
31917811Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction.PLoS One2020
31804971The epigenetic and transcriptional landscape of neuroendocrine prostate cancer.Endocr Relat Cancer2020
30772358Biological Evolution of Castration-resistant Prostate Cancer.Eur Urol Focus2019
29460922Cellular plasticity and the neuroendocrine phenotype in prostate cancer.Nat Rev Urol2018
28315377Patient-derived xenografts: A platform for accelerating translational research in prostate cancer.Mol Cell Endocrinol2018
27784708The Master Neural Transcription Factor BRN2 Is an Androgen Receptor-Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer.Cancer Discov2017
28899970Targeting Prostate Cancer Subtype 1 by Forkhead Box M1 Pathway Inhibition.Clin Cancer Res2017
26880966The Androgen Receptor Bridges Stem Cell-Associated Signaling Nodes in Prostate Stem Cells.Stem Cells Int2016
25934687Regulation of tumor cell plasticity by the androgen receptor in prostate cancer.Endocr Relat Cancer2015
26011941Inhibition of RSK with the novel small-molecule inhibitor LJI308 overcomes chemoresistance by eliminating cancer stem cells.Oncotarget2015
24648416YB-1 transforms human mammary epithelial cells through chromatin remodeling leading to the development of basal-like breast cancer.Stem Cells2014
21423216YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplification.Oncogene2011
21576761YB-1 drives preneoplastic progression: Insight into opportunities for cancer prevention.Oncotarget2011
20332234Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance.Cancer Res2010
19151767Profiling YB-1 target genes uncovers a new mechanism for MET receptor regulation in normal and malignant human mammary cells.Oncogene2009
19887553Small interfering RNA library screen of human kinases and phosphatases identifies polo-like kinase 1 as a promising new target for the treatment of pediatric rhabdomyosarcomas.Mol Cancer Ther2009
18662396Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus.BMC Genomics2008
19036157Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells.Breast Cancer Res2008
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Collaborators

Amina Zoubeidi
University of British Columbia
Co-authored papers 14
Himisha Beltran
Dana-Farber Cancer Institute
Co-authored papers 5
Luke A Selth
Adelaide Medical School, University of Adelaide
Co-authored papers 3
Yuzhuo Wang
University of British Columbia
Co-authored papers 2
Musaddeque Ahmed
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
James C Cross
University of Calgary
Co-authored papers 2
Felix Y Feng
UCSF Medical Center-Mount Zion
Co-authored papers 2
Ladan Fazli
University of British Columbia
Co-authored papers 2
Martin E Gleave
University of British Columbia
Co-authored papers 2
Housheng Hansen He
Princess Margaret Cancer Center, University Health Network, University of Toronto
Co-authored papers 2
Martin Hirst
University of British Columbia
Co-authored papers 1
Parisa Mazrooei
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Michael Fraser
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Junjie T Hua
School of Public Health, Sun Yat-sen University
Co-authored papers 1
Gordon B Mills
Knight Cancer Institute, Oregon Health and Sciences University
Co-authored papers 1
Faraz Hach
University of British Columbia
Co-authored papers 1
Ruth Isserlin
University of Toronto
Co-authored papers 1
Matthew L Freedman
Dana-Farber Cancer Institute
Co-authored papers 1
Timothy J Triche
Center for Epigenetics, Van Andel Research Institute
Co-authored papers 1
Stanley Zhou
Princess Margaret Cancer Research Centre
Co-authored papers 1
Mark A Rubin
University of Bern
Co-authored papers 1
Kathleen E Houlahan
University of California los angeles
Co-authored papers 1
Yong Zeng
College of Life Science, Hunan Normal University
Co-authored papers 1
Miranda Wang
Princess Margaret Cancer Center/University Health Network
Co-authored papers 1
Alexander W Wyatt
University of British Columbia
Co-authored papers 1
Martin J Walsh
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Colin C Collins
University of British Columbia
Co-authored papers 1
Jihan Xia
University of Oulu
Co-authored papers 1
Neil E Fleshner
University of Toronto
Co-authored papers 1
Elizabeth R Lawlor
Seattle Children's Research Institute
Co-authored papers 1
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