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Author Details

Judy Lieberman
Boston Children's Hospital
1978
249
94
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36791099The SET oncoprotein promotes estrogen-induced transcription by facilitating establishment of active chromatin.Proc Natl Acad Sci U S A2023
37487070Disulfiram blocks inflammatory TLR4 signaling by targeting MD-2.Proc Natl Acad Sci U S A2023
37830822Correction for Song et al., "Sustained Small Interfering RNA-Mediated Human Immunodeficiency Virus Type 1 Inhibition in Primary Macrophages".J Virol2023
37020026The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells.Nature2023
37150885Accumulation of Neutrophil Phagocytic Antibody Features Tracks With Naturally Acquired Immunity Against Malaria in Children.J Infect Dis2023
37115914Alternative splicing of <i>GSDMB</i> modulates killer lymphocyte-triggered pyroptosis.Sci Immunol2023
36945424ROS-dependent palmitoylation is an obligate licensing modification for GSDMD pore formation.bioRxiv2023
37198495Publisher Correction: The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells.Nature2023
36865189Palmitoylation of gasdermin D directs its membrane translocation and pore formation in pyroptosis.bioRxiv2023
34511601TRIM21 regulates pyroptotic cell death by promoting Gasdermin D oligomerization.Cell Death Differ2022
35757726mTORC1 Inhibition Protects Human Regulatory T Cells From Granzyme-B-Induced Apoptosis.Front Immunol2022
35483404Inflammasome activation in infected macrophages drives COVID-19 pathology.Nature2022
35385861FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation.Nature2022
36138189Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes.Nat Cancer2022
35896754Author Correction: Streptococcal pyrogenic exotoxin B cleaves GSDMA and triggers pyroptosis.Nature2022
35110732Streptococcal pyrogenic exotoxin B cleaves GSDMA and triggers pyroptosis.Nature2022
34611663Inflammasome activation in infected macrophages drives COVID-19 pathology.bioRxiv2022
33397791Lighting a Fire: Can We Harness Pyroptosis to Ignite Antitumor Immunity?Cancer Immunol Res2021
33883744Gasdermin D pore structure reveals preferential release of mature interleukin-1.Nature2021
33627408Immunotherapy for breast cancer using EpCAM aptamer tumor-targeted gene knockdown.Proc Natl Acad Sci U S A2021
33692549Channelling inflammation: gasdermins in physiology and disease.Nat Rev Drug Discov2021
35058659The Lysosomal Rag-Ragulator Complex Licenses RIPK1 and Caspase-8-mediated Pyroptosis by <i>Yersinia</i>.Science2021
34710137Disulfiram use is associated with lower risk of COVID-19: A retrospective cohort study.PLoS One2021
34785597Decidual NK cells kill Zika virus-infected trophoblasts.Proc Natl Acad Sci U S A2021
34401873SARS-CoV-2 infects blood monocytes to activate NLRP3 and AIM2 inflammasomes, pyroptosis and cytokine release.Res Sq2021
34678046NLRP3 inflammasome activation triggers gasdermin D-independent inflammation.Sci Immunol2021
34099558STING inhibitors target the cyclic dinucleotide binding pocket.Proc Natl Acad Sci U S A2021
34373622Inflammasome activation at the crux of severe COVID-19.Nat Rev Immunol2021
33432229γδ T cells suppress Plasmodium falciparum blood-stage infection by direct killing and phagocytosis.Nat Immunol2021
32367036FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation.Nat Immunol2020
31851327Correction: G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits.J Cell Biol2020
32004099Knocking 'em Dead: Pore-Forming Proteins in Immune Defense.Annu Rev Immunol2020
33277372Lighting a fire on the reef.Sci Immunol2020
33208369CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy.Sci Adv2020
32913355Contributions of IFN-γ and granulysin to the clearance of Plasmodium yoelii blood stage.PLoS Pathog2020
32995777SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism.bioRxiv2020
32822574Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts.Cell2020
32188940Gasdermin E suppresses tumour growth by activating anti-tumour immunity.Nature2020
32518184<i>Tombusvirus</i> p19 Captures RNase III-Cleaved Double-Stranded RNAs Formed by Overlapping Sense and Antisense Transcripts in Escherichia coli.mBio2020
31112765Granulysin: killer lymphocyte safeguard against microbes.Curr Opin Immunol2019
31492708Gasdermin D activity in inflammation and host defense.Sci Immunol2019
31044053Tumor-secreted extracellular vesicles promote the activation of cancer-associated fibroblasts via the transfer of microRNA-125b.J Extracell Vesicles2019
29395345Diagnostic Potential of Imaging Flow Cytometry.Trends Biotechnol2018
29997117miR-196b target screen reveals mechanisms maintaining leukemia stemness with therapeutic potential.J Exp Med2018
30038217Cytotoxic CD8<sup>+</sup> T cells recognize and kill Plasmodium vivax-infected reticulocytes.Nat Med2018
30200806Unveiling the RNA World.N Engl J Med2018
30532754Myeloid Cells in Intact Human Cervical Explants Capture HIV and Can Transmit It to CD4 T Cells.Front Immunol2018
29779946PNPT1 Release from Mitochondria during Apoptosis Triggers Decay of Poly(A) RNAs.Cell2018
29670239Resistance of HIV-infected macrophages to CD8<sup>+</sup> T lymphocyte-mediated killing drives activation of the immune system.Nat Immunol2018
29695864Cryo-EM structure of the gasdermin A3 membrane pore.Nature2018
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Collaborators

Dana-Farber Cancer Institute
Co-authored papers 14
Center for Blood Research and the Department of Pediatrics, Harvard Medical School
Co-authored papers 12
Harvard Medical School
Co-authored papers 6
Co-authored papers 6
Co-authored papers 6
Albert Einstein College of Medicine
Co-authored papers 5
Co-authored papers 5
Ragon Institute of Mass General
Co-authored papers 5
University of Melbourne
Co-authored papers 4
Broad Institute of MIT and Harvard
Co-authored papers 3
Sheffield Institute for Translational Neuroscience, University of Sheffield
Co-authored papers 3
University of Texas San Antonio
Co-authored papers 3
Cardiovascular Research Institute, University of California san francisco
Co-authored papers 3
Co-authored papers 3
Yale School of Medicine
Co-authored papers 2
Co-authored papers 2
Johns Hopkins University School of Medicine
Co-authored papers 2
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Co-authored papers 2
National Institute on Aging (NIA), National Institutes of Health (NIH)
Co-authored papers 2
Massachusetts General Hospital
Co-authored papers 2
Ragon Institute of MGH
Co-authored papers 2
University of Georgia
Co-authored papers 2
Center for AIDS Research, University of California San Diego
Co-authored papers 2
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Yale University School of Medicine
Co-authored papers 2
Yale University
Co-authored papers 2
Max Delbruck Center for Molecular Medicine in the Helmholtz Association (MDC)
Co-authored papers 2
Co-authored papers 2