Author details

Full Name

Lei Zhao

Affiliation

ORCID

Career Start Year

2007

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37205196	A multiplexed assay for quantifying immunomodulatory proteins supports correlative studies in immunotherapy clinical trials.	Front Oncol	2023
36259971	Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety.	Cancer Discov	2023
37643636	Hormone Receptor-Positive Breast Cancer Sensitive to Pembrolizumab: Evidence of the Pathogenicity of the MLH1 Variant 1835del3.		2023
37478973	Monitoring Both Extended and Tryptic Forms of Stable Isotope-Labeled Standard Peptides Provides an Internal Quality Control of Proteolytic Digestion in Targeted Mass Spectrometry-Based Assays.		2023
36301140	Preserving the Phosphoproteome of Clinical Biopsies Using a Quick-Freeze Collection Device.	Biopreserv Biobank	2022
34359745	Targeted Mass Spectrometry Enables Quantification of Novel Pharmacodynamic Biomarkers of ATM Kinase Inhibition.	Cancers (Basel)	2021
34136904	Quantification of Human Epidermal Growth Factor Receptor 2 by Immunopeptide Enrichment and Targeted Mass Spectrometry in Formalin-Fixed Paraffin-Embedded and Frozen Breast Cancer Tissues.	Clin Chem	2021
34858420	Targeted Mass Spectrometry Enables Multiplexed Quantification of Immunomodulatory Proteins in Clinical Biospecimens.	Front Immunol	2021
34671754	Targeted mass spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP Kinase, and AKT signaling.	Cell Rep Methods	2021
29605812	Targeted mass spectrometry enables robust quantification of FANCD2 mono-ubiquitination in response to DNA damage.	DNA Repair (Amst)	2018
30385821	pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry.	Br J Cancer	2018
29474155	A Multiplexed Mass Spectrometry-Based Assay for Robust Quantification of Phosphosignaling in Response to DNA Damage.	Radiat Res	2018
27935710	Quantification of ATP7B Protein in Dried Blood Spots by Peptide Immuno-SRM as a Potential Screen for Wilson's Disease.	Journal of Proteome Research	2017
28477121	Peptide Immunoaffinity Enrichment with Targeted Mass Spectrometry: Application to Quantification of ATM Kinase Phospho-Signaling.	Methods in Molecular Biology	2017
26621847	Immobilized Metal Affinity Chromatography Coupled to Multiple Reaction Monitoring Enables Reproducible Quantification of Phospho-signaling.	Mol Cell Proteomics	2016
27094115	Commercially available antibodies can be applied in quantitative multiplexed peptide immunoaffinity enrichment targeted mass spectrometry assays.	Proteomics	2016
25987412	Peptide Immunoaffinity Enrichment and Targeted Mass Spectrometry Enables Multiplex, Quantitative Pharmacodynamic Studies of Phospho-Signaling.	Mol Cell Proteomics	2015
26302155	Antibody-Coupled Magnetic Beads Can Be Reused in Immuno-MRM Assays To Reduce Cost and Extend Antibody Supply.	Journal of Proteome Research	2015
26121405	Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.	Nat Methods	2015
24568200	High-affinity recombinant antibody fragments (Fabs) can be applied in peptide enrichment immuno-MRM assays.	Journal of Proteome Research	2014
24317253	Demonstrating the feasibility of large-scale development of standardized assays to quantify human proteins.	Nat Methods	2014
22199228	Interlaboratory evaluation of automated, multiplexed peptide immunoaffinity enrichment coupled to multiple reaction monitoring mass spectrometry for quantifying proteins in plasma.	Mol Cell Proteomics	2012
22577026	Multiplexed quantification of estrogen receptor and HER2/Neu in tissue and cell lysates by peptide immunoaffinity enrichment mass spectrometry.	Proteomics	2012
22203691	Sequential multiplexed analyte quantification using peptide immunoaffinity enrichment coupled to mass spectrometry.	Mol Cell Proteomics	2012
21685906	A targeted proteomics-based pipeline for verification of biomarkers in plasma.	Nat Biotechnol	2011
21245105	Evaluation of large scale quantitative proteomic assay development using peptide affinity-based mass spectrometry.	Mol Cell Proteomics	2011
21841765	Quantification of proteins using peptide immunoaffinity enrichment coupled with mass spectrometry.	J Vis Exp	2011
19961853	Automated screening of monoclonal antibodies for SISCAPA assays using a magnetic bead processor and liquid chromatography-selected reaction monitoring-mass spectrometry.	Journal of Immunological Methods	2010
19843560	An automated and multiplexed method for high throughput peptide immunoaffinity enrichment and multiple reaction monitoring mass spectrometry-based quantification of protein biomarkers.	Molecular and Cellular Proteomics	2010
19561596	Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma.	Nat Biotechnol	2009
17241609	Antibody-based enrichment of peptides on magnetic beads for mass-spectrometry-based quantification of serum biomarkers.	Analytical Biochemistry	2007
17711321	Integrated pipeline for mass spectrometry-based discovery and confirmation of biomarkers demonstrated in a mouse model of breast cancer.	J Proteome Res	2007