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Author Details

Brian L Black
Cardiovascular Research Institute, University of California san francisco
1992
91
48
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36908666TCF7L1 Exacerbates Abdominal Aortic Aneurysm Prevalence and Severity.JACC Basic Transl Sci2023
37551662Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.Elife2023
36994838A Mesp1-dependent developmental breakpoint in transcriptional and epigenomic specification of early cardiac precursors.Development2023
36516837An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair.Cell Stem Cell2023
35182466Transcription factor protein interactomes reveal genetic determinants in heart disease.Cell2022
35649376Differential Etv2 threshold requirement for endothelial and erythropoietic development.Cell Rep2022
35938400Transcription Factor GATA4 Regulates Cell Type-Specific Splicing Through Direct Interaction With RNA in Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitors.Circulation2022
36103516Cold shock domain-containing protein E1 is a posttranscriptional regulator of the LDL receptor.Sci Transl Med2022
35896140Transcriptional regulation of vascular smooth muscle cell proliferation, differentiation and senescence: Novel targets for therapy.Vascul Pharmacol2022
33976150Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE.Nat Commun2021
33622983Control of ribosomal protein synthesis by the Microprocessor complex.Sci Signal2021
32380032Presynaptic Homeostasis Opposes Disease Progression in Mouse Models of ALS-Like Degeneration: Evidence for Homeostatic Neuroprotection.Neuron2020
33044128ATAC-Seq Reveals an <i>Isl1</i> Enhancer That Regulates Sinoatrial Node Development and Function.Circ Res2020
33040635Genome-Wide Analysis Identifies an Essential Human TBX3 Pacemaker Enhancer.Circ Res2020
30521808Cardiovascular development and survival require Mef2c function in the myocardial but not the endothelial lineage.Dev Biol2019
31217582Noncoding deletions reveal a gene that is critical for intestinal function.Nature2019
30735130Venous endothelin modulates responsiveness of cardiac sympathetic axons to arterial semaphorin.Elife2019
30217225Genomic analysis of transcriptional networks directing progression of cell states during MGE development.Neural Dev2018
28072389Suppression of <i>C9orf72</i> RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106.Elife2017
28351867Cooperative activation of cardiac transcription through myocardin bridging of paired MEF2 sites.Development2017
26086993Identification of novel Fgf enhancers and their role in dental evolution.Evol Dev2016
27647901Fast revascularization of the injured area is essential to support zebrafish heart regeneration.Proc Natl Acad Sci U S A2016
27049946Modulation of tissue repair by regeneration enhancer elements.Nature2016
26811383MEF2C regulates outflow tract alignment and transcriptional control of Tdgf1.Development2016
25794678Mef2c-F10N enhancer driven β-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells.Dev Biol2015
26160899Endothelin signaling activates Mef2c expression in the neural crest through a MEF2C-dependent positive-feedback transcriptional pathway.Development2015
25992543Developmental biology: Diversity in the lymphatic vasculature.Nature2015
25789156Myocyte enhancer factor 2C function in skeletal muscle is required for normal growth and glucose metabolism in mice.Skelet Muscle2015
25179465An arterial-specific enhancer of the human endothelin converting enzyme 1 (ECE1) gene is synergistically activated by Sox17, FoxC2, and Etv2.Dev Biol2014
25242327NFATc1 controls skeletal muscle fiber type and is a negative regulator of MyoD activity.Cell Rep2014
25050930Specification of the mouse cardiac conduction system in the absence of Endothelin signaling.Dev Biol2014
23830865ETS factors regulate Vegf-dependent arterial specification.Dev Cell2013
24127591Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants.Proc Natl Acad Sci U S A2013
22056786ETS-dependent regulation of a distal Gata4 cardiac enhancer.Dev Biol2012
22449847Transcription factor pathways and congenital heart disease.Curr Top Dev Biol2012
22406820Regulation of endothelial and hematopoietic development by the ETS transcription factor Etv2.Curr Opin Hematol2012
21185281Hand2 function in second heart field progenitors is essential for cardiogenesis.Dev Biol2011
21989916Vascular endothelial and endocardial progenitors differentiate as cardiomyocytes in the absence of Etsrp/Etv2 function.Development2011
22138689Large-scale discovery of enhancers from human heart tissue.Nat Genet2011
21610032The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10.Development2011
21633168FGF-dependent regulation of VEGF receptor 2 expression in mice.J Clin Invest2011
20135106Development of the endocardium.Pediatr Cardiol2010
21145505Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanism.Dev Cell2010
20729851ChIP-Seq identification of weakly conserved heart enhancers.Nat Genet2010
20692247Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer.Dev Biol2010
19217421Transcriptional control of endothelial cell development.Dev Cell2009
19580802Isl1 is a direct transcriptional target of Forkhead transcription factors in second-heart-field-derived mesoderm.Dev Biol2009
19745787Identification and characterization of novel polymorphisms in the basal promoter of the human transporter, MATE1.Pharmacogenet Genomics2009
19777593An endoderm-specific transcriptional enhancer from the mouse Gata4 gene requires GATA and homeodomain protein-binding sites for function in vivo.Dev Dyn2009
19445916Maintenance of blastemal proliferation by functionally diverse epidermis in regenerating zebrafish fins.Dev Biol2009
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Collaborators

Co-authored papers 13
Lawrence Berkeley National Laboratory
Co-authored papers 10
Universidad Pablo de Olavide, Universidad de Sevilla
Co-authored papers 7
Gladstone Institutes of Cardiovascular Disease, Gladstone Institutes
Co-authored papers 7
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Co-authored papers 6
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Gladstone Institutes San Francisco
Co-authored papers 6
Gladstone Institute of Data Science and Biotechnology, Gladstone Institutes
Co-authored papers 5
Co-authored papers 4
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Gladstone Institutes
Co-authored papers 4
SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, University of Cape Town
Co-authored papers 4
University of California san francisco
Co-authored papers 4
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Co-authored papers 3
Co-authored papers 3
Gladstone Institutes of Cardiovascular Disease, Gladstone Institutes
Co-authored papers 3
Cardiovascular Research Institute, University of California San Francisco
Co-authored papers 3
University of California Merced
Co-authored papers 3
Gladstone Institutes San Francisco
Co-authored papers 3
Co-authored papers 3
University of California San Francisco
Co-authored papers 3
Baylor College of Medicine
Co-authored papers 3
University of California San Diego
Co-authored papers 3
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University of California San Francisco
Co-authored papers 2
Australian Regenerative Medicine Institute, Monash University
Co-authored papers 2
Lawrence Berkeley National Laboratory
Co-authored papers 2
Victor Chang Cardiac Research Institute
Co-authored papers 2
Center for Visualization, Washington State University
Co-authored papers 2
University of California at San Diego
Co-authored papers 2